Levothyroxine sodium side effects by duration, gender and age - a phase IV clinical study of FDA data
Summary:
Side effects are reported by people who take Levothyroxine sodium. Common side effects include drug ineffective among females and death among males.
The phase IV clinical study is created by eHealthMe based on 96,297 reports from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
With medical big data and AI algorithms, eHealthMe enables everyone to run phase IV clinical trial to detect adverse drug outcomes and monitor effectiveness. Our original studies have been referenced on 600+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Most recently, phase IV clinial trails for COVID 19 vaccines have been added, check here.
96,297 people who take Levothyroxine Sodium and have side effects are studied.
What is Levothyroxine Sodium?
Levothyroxine sodium has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 102,984 Levothyroxine sodium users for its effectiveness, alternative drugs and more.
Number of Levothyroxine sodium reports submitted per year:

Levothyroxine sodium side effects by time on the drug *:
Levothyroxine sodium side effects by gender *:
Levothyroxine sodium side effects by age *:
* Approximation only. Some reports may have incomplete information.
Do you take Levothyroxine sodium?
Personalize this study to your gender and ageHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
How the study uses the data?
The study is based on levothyroxine sodium (the active ingredients of Levothyroxine sodium) and Levothyroxine sodium (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered.
Related studies
Alternative drugs to, pros and cons of Levothyroxine sodium:
- Levothyroxine sodium (102,984 reports)
Common Levothyroxine sodium side effects:
- Abasia (inability to walk): 369 reports
- Abdominal discomfort: 974 reports
- Abdominal distension: 918 reports
- Abdominal pain: 2,208 reports
- Abdominal pain lower: 209 reports
- Abdominal pain upper: 1,606 reports
- Abnormal behavior: 301 reports
- Abnormal dreams: 212 reports
- Abortion spontaneous (naturally occurring miscarriage): 128 reports
- Abscess (pus): 143 reports
- Accidental exposure: 175 reports
- Accidental overdose (therapeutic agent): 149 reports
- Acne (skin problems that cause pimples): 167 reports
- Activated partial thromboplastin time prolonged: 103 reports
- Activities of daily living impaired: 274 reports
- Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood): 118 reports
- Acute kidney failure: 1,435 reports
- Acute myocardial infarction (acute heart attack): 301 reports
- Acute respiratory failure: 195 reports
- Acute upper airway obstruction (blockage occurs in the upper airway): 120 reports
- Adrenal insufficiency (condition in which the adrenal glands do not produce adequate amounts of steroids): 169 reports
- Adverse drug reaction: 340 reports
- Adverse event: 231 reports
- Ageusia (loss of taste functions of the tongue): 230 reports
- Aggression: 348 reports
- Agitation (state of anxiety or nervous excitement): 1,043 reports
- Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 1,071 reports
- Alanine aminotransferase increased: 900 reports
- Allergic rhinitis: 104 reports
- Altered state of consciousness (altered state of mind): 115 reports
- Anaemia (lack of blood): 2,487 reports
- Anal fissure: 125 reports
- Anaphylaxis (serious allergic reaction that is rapid in onset and may cause death): 321 reports
- Anger: 213 reports
- Angioedema (rapid swelling of the dermis): 298 reports
- Anhedonia (inability to experience pleasure from activities usually found enjoyable): 279 reports
- Ankle fracture: 129 reports
- Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight): 502 reports
- Anti-erythropoietin antibody positive: 109 reports
- Anuria (failure of the kidneys to produce urine): 131 reports
- Aortic valve incompetence: 114 reports
- Aplasia pure red cell (type of anaemia affecting the precursors to red blood cells but not to white blood cells): 144 reports
- Appetite - decreased (decreased appetite occurs when you have a reduced desire to eat): 1,995 reports
- Appetite - increased (increased appetite is when you want to eat much more often or in larger quantities than your body requires): 229 reports
- Application site erythema (redness of the skin at application site): 117 reports
- Ards (acute respiratory distress syndrome) (sudden failure of the respiratory (breathing) system): 207 reports
- Arrhythmias (irregular heartbeat): 1,447 reports
- Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery): 195 reports
- Arthritis (form of joint disorder that involves inflammation of one or more joints): 678 reports
- Arthropathy: 369 reports
- Ascites (accumulation of fluid in the abdominal cavity): 314 reports
- Aseptic necrosis (the death of bone tissue due to a lack of blood supply): 245 reports
- Aspartate aminotransferase increased: 835 reports
- Asphyxia (a condition in which there is an extreme decrease in the concentration of oxygen in the body): 119 reports
- Asthma: 721 reports
- Atelectasis (partial or complete collapse of the lung): 272 reports
- Atherosclerosis (disorder of the arteries): 223 reports
- Atrial fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1,523 reports
- Atrial septal defect (an abnormal opening between the left and right atria of the heart): 115 reports
- Atrioventricular block (heart block): 107 reports
- Atrioventricular block first degree (heart block first degree): 121 reports
- Back disorder: 116 reports
- Back pain: 2,065 reports
- Bacterial infection: 127 reports
- Balance disorder: 1,088 reports
- Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills): 147 reports
- Belching (release of gas from the digestive tract): 158 reports
- Bipolar disorder (mood disorder): 101 reports
- Birth control: 115 reports
- Bladder disorder: 127 reports
- Bleeding disorders: 188 reports
- Bleeding into the skin: 172 reports
- Blindness: 220 reports
- Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure): 452 reports
- Blood albumin decreased: 182 reports
- Blood alkaline phosphatase increased: 459 reports
- Blood bilirubin increased: 403 reports
- Blood calcium decreased: 295 reports
- Blood calcium increased: 125 reports
- Blood creatine phosphokinase increased: 437 reports
- Blood creatinine increased: 968 reports
- Blood glucose decreased: 332 reports
- Blood glucose increased: 1,242 reports
- Blood lactate dehydrogenase increased: 232 reports
- Blood potassium decreased: 387 reports
- Blood pressure fluctuation: 223 reports
- Blood pressure management: 234 reports
- Blood pressure systolic increased: 227 reports
- Blood sodium decreased: 303 reports
- Blood test: 101 reports
- Blood thyroid stimulating hormone decreased: 293 reports
- Blood thyroid stimulating hormone increased: 644 reports
- Blood urea increased: 403 reports
- Blood urine present: 136 reports
- Body height decreased: 160 reports
- Body temperature decreased: 103 reports
- Body temperature increased: 161 reports
- Bone disorder: 261 reports
- Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries): 102 reports
- Bone marrow failure: 129 reports
- Bone pain: 554 reports
- Bradycardia (abnormally slow heart action): 762 reports
- Breast cancer: 323 reports
- Breast cancer female: 114 reports
- Breast pain: 126 reports
- Breathing difficulty: 4,680 reports
- Breathing - slowed or stopped: 161 reports
- Broken bone: 236 reports
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 826 reports
- Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi): 141 reports
- Bundle branch block left (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the left ventricle): 151 reports
- Bundle branch block right (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the right ventricle): 158 reports
- Burning sensation: 591 reports
- Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder): 180 reports
- Candidiasis (candidiasis or thrush is a fungal infection): 129 reports
- Cardiac arrest: 589 reports
- Cardiac disorder: 581 reports
- Cardiac failure: 845 reports
- Cardiac failure congestive: 1,038 reports
- Cardiac murmur (an heart sound in valve abnormality): 226 reports
- Cardioactive drug level increased: 165 reports
- Cardiogenic shock (inadequate circulation of blood): 105 reports
- Cardiomyopathy (weakening of the heart muscle): 174 reports
- Cardio-respiratory arrest (sudden dysfunction of heart and lungs): 306 reports
- Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling): 195 reports
- Cataract (clouding of the lens inside the eye): 492 reports
- Cellulitis (infection under the skin): 636 reports
- Cerebral atrophy (decrement in size of brain): 109 reports
- Cerebral haemorrhage (bleeding within the brain): 239 reports
- Cerebral infarction (less blood supply to brain resulting tissue damage): 191 reports
- Chest pain: 2,825 reports
- Chills (felling of cold): 1,024 reports
- Cholecystitis (infection of gallbladder): 202 reports
- Cholecystitis acute (rapid infection of gallbladder): 108 reports
- Cholecystitis chronic (long lasting infection of gallbladder): 169 reports
- Cholestasis (a condition where bile cannot flow from the liver to the duodenum): 230 reports
- Chronic kidney disease: 329 reports
- Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe): 578 reports
- Chronic thyroiditis (long lasting inflammation of thyroid gland): 115 reports
- Circulatory collapse: 257 reports
- Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving): 555 reports
- Colitis (inflammation of colon): 349 reports
- Colon cancer: 101 reports
- Colonic polyp (extra part of colon tissue grow in intestine): 184 reports
- Completed suicide (act of taking one's own life): 420 reports
- Confusion: 698 reports
- Confusional state: 1,855 reports
- Conjunctivitis (pink eye): 111 reports
- Consciousness - decreased: 397 reports
- Constipation: 2,571 reports
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 845 reports
- Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly): 123 reports
- Coronary artery occlusion (complete obstruction of blood flow in a coronary artery): 172 reports
- Coronary heart disease (narrowing or blockage of the coronary arteries): 343 reports
- Cough: 2,216 reports
- Coughing up blood: 295 reports
- C-reactive protein increased: 386 reports
- Creatinine renal clearance decreased: 139 reports
- Crohn's disease (condition that causes inflammation of the gastrointestinal tract): 142 reports
- Crying: 249 reports
- Cuts and puncture wounds: 162 reports
- Cyst (a closed sac): 130 reports
- Cytolytic hepatitis (dissolution or destruction of a liver cell): 221 reports
- Death: 2,099 reports
- Decreased interest: 108 reports
- Deep venous thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 782 reports
- Deformity (disfigurement): 137 reports
- Dehydration (dryness resulting from the removal of water): 1,882 reports
- Delirium (wild excitement): 347 reports
- Delusion (a false belief or opinion): 121 reports
- Dementia (madness): 196 reports
- Dental caries: 157 reports
- Depressed level of consciousness: 640 reports
- Depressed mood: 445 reports
- Depression: 2,421 reports
- Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it): 340 reports
- Device related infection: 116 reports
- Diabetes: 662 reports
- Diabetes mellitus inadequate control: 242 reports
- Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies): 173 reports
- Diarrhea: 5,019 reports
- Difficulty in walking: 217 reports
- Diffuse interstitial lung disease (group of lung diseases affecting the interstitium): 101 reports
- Diplopia (double vision): 270 reports
- Disability: 111 reports
- Discomfort: 256 reports
- Disease progression: 454 reports
- Disease recurrence: 157 reports
- Disseminated intravascular coagulation (systemic activation of blood coagulation): 139 reports
- Disturbance in attention: 560 reports
- Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall): 275 reports
- Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body): 217 reports
- Dizziness: 4,577 reports
- Drowsiness: 1,947 reports
- Drug abuse and dependence: 110 reports
- Drug administration error: 179 reports
- Drug dependence: 138 reports
- Drug effect decreased: 480 reports
- Drug eruption (adverse drug reaction of the skin): 150 reports
- Drug exposure during pregnancy: 285 reports
- Drug hypersensitivity: 953 reports
- Drug ineffective: 4,562 reports
- Drug intolerance (drug sensitivity): 441 reports
- Drug level increased: 160 reports
- Drug toxicity: 255 reports
- Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation): 297 reports
- Dry eyes (lack of adequate tears): 284 reports
- Dry mouth: 902 reports
- Dry skin: 579 reports
- Dyskinesia (abnormality or impairment of voluntary movement): 355 reports
- Dyspnea exertional: 458 reports
- Dysstasia (difficulty in standing): 245 reports
- Ear pain: 256 reports
- Eating disorder: 181 reports
- Ecchymosis (a discoloration of the skin resulting from bleeding underneath): 210 reports
- Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 223 reports
- Ejection fraction decreased (systolic heart failure): 160 reports
- Electrocardiogram qt prolonged: 508 reports
- Electrolyte imbalance: 161 reports
- Emotional disorder: 205 reports
- Emotional distress: 481 reports
- Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs): 150 reports
- Encephalopathy (functioning of the brain is affected by some agent or condition): 256 reports
- Enlarged heart: 223 reports
- Eosinophilia (eosinophil count in the peripheral blood exceeds): 160 reports
- Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 237 reports
- Erection problems: 117 reports
- Erythema multiforme (a type of hypersensitivity reaction): 321 reports
- Escherichia infection (bacterial infection by escherichia coli): 107 reports
- Exostosis (formation of new bone on the surface of a bone): 160 reports
- Extrasystoles: 110 reports
- Eye disorder: 248 reports
- Eye haemorrhage (bleeding in the eye): 127 reports
- Eye irritation: 167 reports
- Eyelid oedema (eyelids are swollen and contain excessive fluid): 130 reports
- Eye pain: 312 reports
- Eye pruritus (eye itching): 182 reports
- Eye swelling: 224 reports
- Face oedema (swelling of face): 247 reports
- Faecal incontinence (a lack of control over passing stool): 127 reports
- Faeces discolored: 233 reports
- Fainting (loss of consciousness and postural tone): 1,329 reports
- Fall: 3,967 reports
- Fatigue (feeling of tiredness): 7,190 reports
- Fear: 256 reports
- Febrile neutropenia (fever with reduced white blood cells): 308 reports
- Feeling cold: 339 reports
- Feeling hot: 568 reports
- Feeling jittery: 190 reports
- Femur fracture: 462 reports
- Fever: 2,872 reports
- Fibromyalgia (a long-term condition which causes pain all over the body): 238 reports
- Flank pain (a distressing sensation experienced around the lower back and the upper abdomen): 103 reports
- Flatulence (flatus expelled through the anus): 612 reports
- Fluid overload (too much fluid in the blood): 113 reports
- Fluid retention (an abnormal accumulation of fluid in the blood): 412 reports
- Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect): 253 reports
- Foot fracture: 200 reports
- Full blood count decreased: 198 reports
- Fungal infection: 189 reports
- Gait disturbance: 1,536 reports
- Gallbladder disorder: 273 reports
- Gallbladder removal: 138 reports
- Gallstones (stone formation by bile component): 634 reports
- Gamma-glutamyltransferase increased: 391 reports
- Gastric disorder (disease of stomach): 322 reports
- Gastric ulcer (stomach ulcer): 435 reports
- Gastritis (inflammation of stomach): 425 reports
- Gastritis erosive (a break in the surface layer of the membrane lining the stomach with infection): 170 reports
- Gastroenteritis (inflammation of stomach and intestine): 247 reports
- Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection): 109 reports
- Gastroesophageal reflux disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 964 reports
- Gastrointestinal disorder (functional problems of gastrointestinal tract): 447 reports
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract): 814 reports
- Generalised oedema (swelling all over the body): 140 reports
- General physical health deterioration (weak health status): 1,445 reports
- Gingival bleeding (bleeding gums): 147 reports
- Glaucoma (increased fluid pressure in the eye with vision loss): 153 reports
- Glossodynia (a burning or painful sensation in the tongue): 199 reports
- Glycosylated haemoglobin increased: 141 reports
- Gout (uric acid crystals building up in the body): 222 reports
- Grand mal convulsion (a type of generalized seizure that affects the entire brain): 242 reports
- Groin pain: 104 reports
- Haematemesis (vomiting of blood): 324 reports
- Haematochezia (passage of stools containing blood): 436 reports
- Haematocrit decreased: 434 reports
- Haematoma (collection of blood outside the blood vessels): 341 reports
- Haematuria (presence of blood in urine): 320 reports
- Haemoglobin decreased: 1,436 reports
- Haemolytic anaemia (anaemia due to haemolysis): 104 reports
- Haemorrhage (bleeding): 615 reports
- Haemorrhoids (a swollen vein or group of veins in the region of the anus): 408 reports
- Hair loss: 1,608 reports
- Hallucination, auditory (perceiving sounds without auditory stimulus): 108 reports
- Hallucinations (sensations that appear real but are created by your mind): 576 reports
- Hallucination, visual (seeing things that aren't there): 190 reports
- Headache (pain in head): 4,296 reports
- Head discomfort: 112 reports
- Head injury: 1,183 reports
- Hearing impaired: 105 reports
- Hearing loss: 155 reports
- Heart attack: 1,167 reports
- Heart disease: 122 reports
- Heart palpitations (feelings or sensations that your heart is pounding or racing): 1,437 reports
- Heart rate decreased: 376 reports
- Heart rate increased: 849 reports
- Heart rate irregular: 359 reports
- Heavy or prolong menstrual bleeding: 119 reports
- Hemiparesis (weakness on one side of the body): 202 reports
- Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue): 201 reports
- Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure): 118 reports
- Hepatic enzyme increased: 491 reports
- Hepatic failure (liver failure): 372 reports
- Hepatic steatosis (fatty liver disease): 305 reports
- Hepatitis (inflammation of the liver): 317 reports
- Hepatomegaly (abnormal enlargement of the liver): 174 reports
- Hepatotoxicity (chemical-driven liver damage): 107 reports
- Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle): 142 reports
- Herpes zoster: 383 reports
- Hiatal hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm): 265 reports
- High blood cholesterol: 909 reports
- High blood pressure: 3,598 reports
- Hip fracture: 323 reports
- Hip joint replacement: 107 reports
- Hoarseness or changing voice: 497 reports
- Hospitalisation: 352 reports
- Hot flush (sudden feelings of heat): 514 reports
- Hypercalcaemia (elevated calcium (ca+) level in the blood): 197 reports
- Hyperglycemia (high blood sugar): 383 reports
- Hyperhidrosis (abnormally increased sweating): 1,104 reports
- Hyperkalemia (damage to or disease of the kidney): 839 reports
- Hyperlipidaemia (presence of excess lipids in the blood): 283 reports
- Hypernatraemia (an abnormally high plasma concentration of sodium ions): 103 reports
- Hypersensitivity: 1,079 reports
- Hypertensive crisis: 141 reports
- Hyperthyroidism (over activity of the thyroid gland): 426 reports
- Hypoacusis (loss of hearing): 244 reports
- Hypoaesthesia (reduced sense of touch or sensation): 1,243 reports
- Hypoaesthesia oral (reduced sense of touch or sensation in mouth): 104 reports
- Hypocalcaemia (levels of calcium in blood serum are abnormally low): 225 reports
- Hypoglycemia (low blood sugar): 590 reports
- Hypokalemia (low potassium): 746 reports
- Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood): 185 reports
- Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 1,117 reports
- Hypophagia (reduced food intake): 225 reports
- Hypopnea: 118 reports
- Hypotension (abnormally low blood pressure): 2,885 reports
- Hypothermia (body temperature drops below the required temperature for normal metabolism and body functions): 121 reports
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1,488 reports
- Idiopathic pulmonary fibrosis (chronic lung disease): 269 reports
- Ill-defined disorder: 264 reports
- Impaired healing: 406 reports
- Impaired work ability: 121 reports
- Inappropriate antidiuretic hormone secretion: 115 reports
- Incontinence (lack of moderation or self-control): 127 reports
- Increased tendency to bruise (increased tendency to injure the underlying soft tissue or bone): 123 reports
- Indigestion: 963 reports
- Infection: 827 reports
- Inflammation: 430 reports
- Influenza like illness: 586 reports
- Infusion related reaction: 187 reports
- Injection site bruising: 152 reports
- Injection site burning: 125 reports
- Injection site erythema (redness at injection site): 508 reports
- Injection site haematoma (localized swelling filled with blood at injection site): 188 reports
- Injection site haemorrhage (bleeding from injection site): 389 reports
- Injection site irritation: 129 reports
- Injection site pain: 734 reports
- Injection site pruritus (severe itching at injection site): 270 reports
- Injection site reaction: 424 reports
- Injection site swelling: 199 reports
- Injury: 742 reports
- Insomnia (sleeplessness): 2,224 reports
- Intentional overdose: 160 reports
- International normalised ratio increased: 696 reports
- Interstitial lung disease: 323 reports
- Interstitial nephritis (inflammation of the kidney): 118 reports
- Intervertebral disc degeneration (spinal disc degeneration): 226 reports
- Intervertebral disc protrusion (spinal disc protrusion): 290 reports
- Intestinal obstruction: 320 reports
- Iron deficiency anaemia: 141 reports
- Irritability: 478 reports
- Irritable bowel syndrome: 168 reports
- Ischaemic stroke (stroke; caused by an interruption in the flow of blood to the brain): 110 reports
- Itching: 2,373 reports
- Jaundice - yellow skin (a yellowish pigmentation of the skin): 387 reports
- Jaw disorder (jaw disease): 108 reports
- Joint effusion (presence of extra fluid in joint covering): 109 reports
- Joint injury: 181 reports
- Joint pain: 2,994 reports
- Joint range of motion decreased (disease of joint movement): 143 reports
- Joint stiffness: 276 reports
- Joint swelling: 934 reports
- Kidney infection: 165 reports
- Kidney infection (pyelonephritis): 119 reports
- Kidney stones: 304 reports
- Knee joint replacement: 152 reports
- Lacrimation increased: 222 reports
- Lactic acidosis (low ph in body tissues): 273 reports
- Left ventricular failure (left ventricle fails to contract forcefully): 169 reports
- Left ventricular hypertrophy (the thickening of the myocardium (muscle) of the left ventricle of the heart): 114 reports
- Leukocytosis (increased white blood cells): 226 reports
- Leukopenia (less number of white blood cells in blood): 459 reports
- Limb discomfort (discomfort in leg): 209 reports
- Limb injury: 177 reports
- Lip swelling: 245 reports
- Liver disorder (liver diseases): 292 reports
- Localised infection (infection at the single location): 187 reports
- Local swelling (swelling at the site of some application of substance or injury): 136 reports
- Loss of consciousness: 1,270 reports
- Lower limb fracture: 124 reports
- Lower respiratory tract infection: 351 reports
- Low tissue oxygen: 357 reports
- Low turnover osteopathy (slow removal of old bone and its replacement by new bone): 139 reports
- Lung disorder (lung disease): 392 reports
- Lung infection: 150 reports
- Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung): 148 reports
- Lung neoplasm (tumour of lung): 129 reports
- Lung neoplasm malignant (cancer tumour of lung): 129 reports
- Lymph follicular hypertrophy (an increase in the size of the lymph node follicles): 382 reports
- Lymphocyte count decreased: 127 reports
- Lymphoma (cancer that begins in immune system cells): 119 reports
- Lymphopenia (an abnormally low level of lymphocytes in the blood): 102 reports
- Macular degeneration (painless eye condition that leads to the gradual loss of central vision): 112 reports
- Malaise (a feeling of general discomfort or uneasiness): 3,200 reports
- Malignant neoplasm progression (cancer tumour came back): 463 reports
- Malnutrition (condition that results from eating a diet in which certain nutrients are lacking): 156 reports
- Mania (a state of abnormally elevated or irritable mood): 171 reports
- Maternal drugs affecting foetus (chemical affecting the baby before birth taken by mother): 148 reports
- Maternal exposure during pregnancy (use of substance during pregnancy): 274 reports
- Melaena (the passage of black, tarry stools): 256 reports
- Memory loss: 1,628 reports
- Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 300 reports
- Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition): 190 reports
- Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation): 418 reports
- Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body): 284 reports
- Metastases to bone (cancer spreads to bone): 145 reports
- Metastases to liver (cancer spreads to liver): 169 reports
- Micturition urgency (urgency to pass the urine): 145 reports
- Middle insomnia (difficulty returning to sleep after awakening either in the middle of the night): 133 reports
- Migraine (headache): 528 reports
- Mitral valve incompetence (inefficient heart valve): 320 reports
- Mobility decreased (ability to move is reduced): 564 reports
- Mood swings (an extreme or rapid change in mood): 327 reports
- Mouth ulcers: 215 reports
- Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness): 218 reports
- Movement - uncontrolled or slow: 125 reports
- Movement - uncoordinated: 172 reports
- Mucosal inflammation (infection of mucous membrane): 206 reports
- Multi-organ failure (multisystem organ failure): 360 reports
- Multiple injuries: 123 reports
- Multiple myeloma (cancer of the plasma cells): 255 reports
- Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 245 reports
- Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 255 reports
- Muscle aches (muscle pain): 1,704 reports
- Muscle atrophy (a decrease in the mass of the muscle): 126 reports
- Muscle cramps (painful sensations caused by muscle contraction): 120 reports
- Muscle rigidity (muscle stiffness): 108 reports
- Muscle spasms (muscle contraction): 1,588 reports
- Muscle tightness: 131 reports
- Muscle twitching: 308 reports
- Musculoskeletal chest pain (pain in chest muscle or nerve or bones): 180 reports
- Musculoskeletal discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves): 159 reports
- Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 610 reports
- Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 552 reports
- Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 149 reports
- Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased): 214 reports
- Myoclonus (a brief, involuntary twitching of a muscle or a group of muscles): 111 reports
- Myopathy (a muscular disease in which the muscle fibres do not function): 197 reports
- Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 270 reports
- Nasopharyngitis (inflammation of the nasopharynx): 883 reports
- Nausea (feeling of having an urge to vomit): 6,402 reports
- Nausea and vomiting: 3,574 reports
- Neck pain: 573 reports
- Neoplasm malignant (cancer tumour): 301 reports
- Neoplasm progression (growth of tumour): 233 reports
- Neoplasm recurrence (reoccurrence of tumour): 153 reports
- Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease): 125 reports
- Nervousness: 513 reports
- Nervous system disorder (a general class of medical conditions affecting the nervous system): 157 reports
- Neuralgia (pain in one or more nerves): 173 reports
- Neuroleptic malignant syndrome (a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic agents): 108 reports
- Neuropathy peripheral (surface nerve damage): 691 reports
- Neutrophil count decreased (less than normal number of neutrophil a type of blood cell): 205 reports
- Nightmares (unpleasant dreams): 240 reports
- Night sweats (sweating in night): 279 reports
- Nosebleed (bleeding from nose): 656 reports
- Ocular hyperaemia (an abnormally large amount of blood in eye): 135 reports
- Oedema (fluid collection in tissue): 723 reports
- Oedema lower limb (fluid collection in tissue of lower leg): 158 reports
- Oedema peripheral (superficial swelling): 2,362 reports
- Oesophagitis (inflammation of oesophagus): 183 reports
- Oral candidiasis (fungal infection of mouth): 105 reports
- Oral discomfort (pain or irritation in mouth): 110 reports
- Oral pain: 295 reports
- Oropharyngeal pain: 678 reports
- Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up): 502 reports
- Osteoarthritis (a joint disease caused by cartilage loss in a joint): 624 reports
- Osteomyelitis (infection of bone): 230 reports
- Osteonecrosis of jaw (death of bone of jaw): 354 reports
- Osteopenia (a condition where bone mineral density is lower than normal): 225 reports
- Osteoporosis (bones weak and more likely to break): 407 reports
- Otitis (ear infection): 137 reports
- Ovarian cysts (fluid filled sacs of the ovary): 109 reports
- Overdose: 829 reports
- Oxygen saturation decreased: 330 reports
- Pain: 4,033 reports
- Pain in extremity: 2,619 reports
- Pain in jaw: 281 reports
- Pain in limb: 144 reports
- Pain of skin: 106 reports
- Paleness (unusual lightness of skin colour): 322 reports
- Palmar-plantar erythrodysaesthesia syndrome (hand-foot syndrome): 199 reports
- Pancreatitis (inflammation of pancreas): 530 reports
- Pancreatitis acute (sudden inflammation of pancreas): 246 reports
- Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 552 reports
- Panic disorder: 299 reports
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 1,428 reports
- Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur): 136 reports
- Parkinson's disease: 292 reports
- Paroxysmal supraventricular tachycardia: 148 reports
- Pathological fracture (broken bone caused by disease): 135 reports
- Pelvic pain: 115 reports
- Pericardial effusion (fluid around the heart): 277 reports
- Pericarditis (inflammation of the pericardium): 102 reports
- Peripheral coldness: 163 reports
- Peripheral swelling: 628 reports
- Peripheral vascular disorder: 126 reports
- Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs): 141 reports
- Pharyngeal oedema (abnormal accumulation of fluid in the cavities and intercellular spaces of the pharyngeal): 175 reports
- Pharyngitis (inflammation of the pharynx, causing a sore throat): 156 reports
- Pharyngolaryngeal pain: 130 reports
- Photophobia (extreme sensitivity to light): 137 reports
- Photosensitivity reaction: 126 reports
- Pituitary tumor benign: 101 reports
- Platelet count increased: 129 reports
- Pleural effusion (water on the lungs): 959 reports
- Pneumonia: 2,950 reports
- Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree): 207 reports
- Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung): 129 reports
- Pollakiuria (abnormally frequent passage of relatively small quantities or urine): 399 reports
- Polyneuropathy (neurological disorder that occurs when many peripheral nerves throughout the body malfunction simultaneously): 119 reports
- Poor quality sleep: 207 reports
- Post procedural complication: 174 reports
- Premature baby: 171 reports
- Presyncope: 233 reports
- Productive cough: 368 reports
- Progressive multifocal leukoencephalopathy (rapidly progressive neuromuscular disease caused by opportunistic infection of brain cells): 125 reports
- Prostate cancer: 112 reports
- Protein - urine: 158 reports
- Pruritus generalised (generalized itching): 256 reports
- Psoriasis (immune-mediated disease that affects the skin): 357 reports
- Psychomotor hyperactivity (feelings of extreme restlessness): 128 reports
- Psychotic disorder: 174 reports
- Pulmonary congestion (congestion in the lungs): 178 reports
- Pulmonary embolism (blockage of the main artery of the lung): 1,023 reports
- Pulmonary hypertension (increase in blood pressure in the lung artery): 346 reports
- Pulmonary mass: 113 reports
- Pulmonary oedema (fluid accumulation in the lungs): 502 reports
- Purpura (purplish discoloration of the skin): 151 reports
- Quality of life decreased: 111 reports
- Rales (an abnormal respiratory sound characterized by fine crackles): 131 reports
- Rash erythematous (redness of the skin): 365 reports
- Rashes (redness): 3,878 reports
- Rash macular (small, flat red spots): 233 reports
- Rash maculo-papular (red area on the skin that is covered with small confluent bumps): 233 reports
- Rash papular (redness with papule): 166 reports
- Rash pruritic (redness with itching): 467 reports
- Reaction to drug excipients: 125 reports
- Rectal haemorrhage (bleeding from anus): 534 reports
- Red blood cell count decreased: 287 reports
- Red blood cell sedimentation rate increased: 158 reports
- Refractory anaemia (an anaemia which does not respond to treatment): 104 reports
- Renal cyst (kidney cyst): 142 reports
- Renal disorder (kidney disease): 393 reports
- Renal failure acute (rapid kidney dysfunction): 1,599 reports
- Renal failure chronic (long lasting kidney dysfunction): 360 reports
- Renal impairment (severely reduced kidney function): 770 reports
- Renal injury (kidney injury): 173 reports
- Renal tubular necrosis (death of kidney tubules): 135 reports
- Respiratory acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 710 reports
- Respiratory disorder (respiratory disease): 235 reports
- Respiratory distress (difficulty in breathing): 243 reports
- Respiratory rate increased (excess breathing rate/min): 101 reports
- Respiratory tract infection: 167 reports
- Restless leg syndrome (a powerful urge to move your legs): 214 reports
- Retching (strong involuntary effort to vomit): 153 reports
- Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down): 703 reports
- Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints): 693 reports
- Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose): 122 reports
- Rib fracture: 238 reports
- Rickets (softening of bones): 168 reports
- Right ventricular failure (right half of the heart fails to work): 201 reports
- Road traffic accident: 369 reports
- Rotator cuff syndrome (a spectrum of conditions affecting the rotator cuff tendons of the shoulder): 152 reports
- Scar: 161 reports
- Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve): 222 reports
- Scoliosis (a medical condition in which a person's spine is curved from side to side): 120 reports
- Sedation: 469 reports
- Seizures (abnormal excessive or synchronous neuronal activity in the brain): 258 reports
- Sensory disturbance (sense disturbance): 132 reports
- Sepsis (a severe blood infection that can lead to organ failure and death): 938 reports
- Septic shock (shock due to blood infection): 348 reports
- Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time): 203 reports
- Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin): 207 reports
- Sinus bradycardia (an unusually slow heartbeat due to heart disease): 161 reports
- Sinus disorder (disease of sinus): 138 reports
- Sinusitis (inflammation of sinus): 868 reports
- Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node): 191 reports
- Skin blushing/flushing (a sudden reddening of the face, neck): 1,067 reports
- Skin burning sensation: 203 reports
- Skin - clammy: 146 reports
- Skin discoloration: 326 reports
- Skin discoloration - bluish (bluish colour of skin): 148 reports
- Skin disorder (skin disease): 237 reports
- Skin exfoliation (removal of the oldest dead skin cells): 358 reports
- Skin ulcer: 319 reports
- Sleep apnea syndrome: 316 reports
- Sleep disorder: 571 reports
- Small intestinal obstruction (blockage in small intestine): 144 reports
- Sneezing: 123 reports
- Speech disorder: 537 reports
- Speech impairment (adult) (inability to speak (adult)): 722 reports
- Spinal column stenosis (narrowing of spinal column): 159 reports
- Spinal compression fracture (fracture due to spinal compression on bone): 116 reports
- Spinal fracture (fracture in one of vertebrae): 211 reports
- Spinal osteoarthritis (joint cartilage loss in spine): 238 reports
- Splenomegaly (enlargement of spleen): 132 reports
- Stable angina (a constant chest pain): 432 reports
- Staphylococcal infection (an infection with staphylococcus bacteria): 316 reports
- Stomatitis (inflammation of mucous membrane of mouth): 584 reports
- Stress and anxiety: 2,684 reports
- Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 1,048 reports
- Subarachnoid haemorrhage (blood leaks into the space between two membranes that surround the brain): 127 reports
- Subdural haematoma (blood collects between the skull and the surface of the brain): 144 reports
- Suicidal ideation: 566 reports
- Suicide attempt: 315 reports
- Surgery: 240 reports
- Swallowing difficulty: 1,040 reports
- Sweating increased (excess sweating): 143 reports
- Swelling: 652 reports
- Swelling face: 509 reports
- Swollen tongue (swelling of tongue): 384 reports
- Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 149 reports
- Tachypnea: 121 reports
- Tardive dyskinesia (a disorder that involves involuntary movements): 128 reports
- Taste - impaired: 604 reports
- Tenderness (pain or discomfort when an affected area is touched): 150 reports
- Tendonitis (a condition that causes pain and swelling of tendons): 158 reports
- The flu (the flu is caused by an influenza virus): 523 reports
- Therapeutic agent toxicity (poisoning by ability to cure substance): 178 reports
- Therapeutic response decreased (less preventive response): 190 reports
- Therapeutic response unexpected: 255 reports
- Thirst: 193 reports
- Throat irritation: 275 reports
- Throat tightness: 180 reports
- Thrombocytopenia (decrease of platelets in blood): 2,040 reports
- Thrombophlebitis (swelling (inflammation) of a vein caused by a blood clot): 134 reports
- Thrombosis (formation of a blood clot inside a blood vessel): 548 reports
- Thyroid cancer: 125 reports
- Thyroid diseases: 585 reports
- Tinnitus (a ringing in the ears): 381 reports
- Tooth abscess (pus formation in tooth): 259 reports
- Toothaches (tooth pain): 179 reports
- Tooth disorder (tooth disease): 247 reports
- Tooth extraction: 144 reports
- Tooth fracture: 161 reports
- Tooth loss: 136 reports
- Torsade de pointes (a abnormal heart rate with abnormal beating pattern): 125 reports
- Toxic skin eruption (skin breakdown due to toxic substance): 109 reports
- Transaminases increased: 179 reports
- Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow)): 469 reports
- Tremor (trembling or shaking movements in one or more parts of your body): 1,638 reports
- Tricuspid valve incompetence (inefficient heart valve): 182 reports
- Tumor: 147 reports
- Type 2 diabetes: 289 reports
- Ulcerative colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 115 reports
- Unresponsive to stimuli: 271 reports
- Upper gastrointestinal haemorrhage (upper gastrointestinal bleeding): 182 reports
- Upper limb fracture: 151 reports
- Upper respiratory tract infection: 520 reports
- Urinary incontinence (inability to control the flow of urine and involuntary urination): 399 reports
- Urinary retention (the inability to completely or partially empty the bladder): 306 reports
- Urinary tract infection: 2,340 reports
- Urination - excessive at night: 122 reports
- Urination - painful: 347 reports
- Urine output - decreased: 113 reports
- Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream): 114 reports
- Urticaria (rash of round, red welts on the skin that itch intensely): 907 reports
- Vaginal bleeding: 177 reports
- Varicose vein (veins that have become enlarged and tortuous): 154 reports
- Vasculitis (inflammation of a blood vessel or blood vessels): 150 reports
- Ventricular extrasystoles (premature cardiac contraction): 193 reports
- Ventricular fibrillation (abnormally irregular heart rhythm): 119 reports
- Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart): 255 reports
- Viral infection: 289 reports
- Vision blurred: 1,031 reports
- Visual acuity reduced (reduced clearness of vision): 360 reports
- Visual disturbance: 137 reports
- Visual impairment: 624 reports
- Weakness: 5,168 reports
- Weight decreased: 2,706 reports
- Weight increased: 1,997 reports
- Weight loss: 232 reports
- Wheezing (a high-pitched whistling sound made while you breath): 475 reports
- White blood cell count decreased: 994 reports
- White blood cell count increased: 450 reports
- Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance): 225 reports
- Wound: 187 reports
- Wrist fracture: 135 reports
All Levothyroxine sodium side effects from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zWho is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
Recent studies on eHealthMe:
- Diprivan and Xylocaine drug interaction - 13 seconds ago
- Cabergoline and Cardiac Valve Sclerosis - 17 seconds ago
- How effective is Flexeril for Back Pain? - 31 seconds ago
- Docetaxel and Pradaxa drug interaction - 31 seconds ago
- Marcaine and Acne - 32 seconds ago