Mercaptopurine side effects by duration, gender and age - a phase IV clinical study of FDA data
Summary:
Side effects are reported by people who take Mercaptopurine. Common side effects include febrile neutropenia among females and febrile neutropenia among males.
The phase IV clinical study is created by eHealthMe based on 17,728 reports from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
With medical big data and AI algorithms, eHealthMe enables everyone to run phase IV clinical trial to detect adverse drug outcomes and monitor effectiveness. Our original studies have been referenced on 600+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Most recently, phase IV clinial trails for COVID 19 vaccines have been added, check here.
17,728 people who take Mercaptopurine and have side effects are studied.
What is Mercaptopurine?
Mercaptopurine has active ingredients of mercaptopurine. It is often used in crohn's disease. eHealthMe is studying from 17,982 Mercaptopurine users for its effectiveness, alternative drugs and more.
Number of Mercaptopurine reports submitted per year:

Mercaptopurine side effects by time on the drug *:
Mercaptopurine side effects by gender *:
Mercaptopurine side effects by age *:
* Approximation only. Some reports may have incomplete information.
Do you take Mercaptopurine?
Personalize this study to your gender and ageHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
How the study uses the data?
The study is based on mercaptopurine (the active ingredients of Mercaptopurine) and Mercaptopurine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered.
Related studies
Alternative drugs to, pros and cons of Mercaptopurine:
- Mercaptopurine (17,982 reports)
Common Mercaptopurine side effects:
- Abdominal distension: 156 reports
- Abdominal pain: 692 reports
- Abdominal pain upper: 159 reports
- Acute kidney failure: 109 reports
- Acute lymphocytic leukaemia recurrent (cancer in which the bone marrow makes too many lymphocytes-recurrent): 135 reports
- Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 186 reports
- Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 578 reports
- Alanine aminotransferase increased: 286 reports
- Anaemia (lack of blood): 452 reports
- Anaphylaxis (serious allergic reaction that is rapid in onset and may cause death): 127 reports
- Appetite - decreased (decreased appetite occurs when you have a reduced desire to eat): 196 reports
- Arrhythmias (irregular heartbeat): 209 reports
- Aseptic necrosis (the death of bone tissue due to a lack of blood supply): 174 reports
- Aspartate aminotransferase increased: 180 reports
- Back pain: 259 reports
- Bacterial infection: 407 reports
- Blood bilirubin increased: 166 reports
- Blood pressure fluctuation: 129 reports
- Bone marrow failure: 227 reports
- Breathing difficulty: 399 reports
- Bronchopulmonary aspergillosis (lung disorder caused by aspergillus fungi): 195 reports
- Cellulitis (infection under the skin): 218 reports
- Chest pain: 237 reports
- Chills (felling of cold): 196 reports
- Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection): 286 reports
- Colitis (inflammation of colon): 239 reports
- Constipation: 235 reports
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 125 reports
- Cough: 310 reports
- Crohn's disease (condition that causes inflammation of the gastrointestinal tract): 906 reports
- Cytomegalovirus chorioretinitis (infection of choroid and retina of the eye from virus): 162 reports
- Cytomegalovirus infection: 109 reports
- Cytomegalovirus viraemia (cytomegalo virus in blood stream): 137 reports
- Death: 326 reports
- Dehydration (dryness resulting from the removal of water): 195 reports
- Depression: 111 reports
- Diarrhea: 762 reports
- Dizziness: 293 reports
- Drowsiness: 127 reports
- Drug hypersensitivity: 179 reports
- Drug ineffective: 925 reports
- Drug intolerance (drug sensitivity): 130 reports
- Enteritis (inflammation of the small intestine): 152 reports
- Enterobacter infection (infection caused by bacteria of the family enterobacteriaceae): 134 reports
- Fall: 124 reports
- Fatigue (feeling of tiredness): 670 reports
- Febrile bone marrow aplasia (bone marrow greatly decreases or stops production of blood cells): 242 reports
- Febrile neutropenia (fever with reduced white blood cells): 1,401 reports
- Fever: 1,229 reports
- Fungal infection: 206 reports
- Gait disturbance: 118 reports
- Haematochezia (passage of stools containing blood): 134 reports
- Haematotoxicity (toxins that destroy red blood cells): 241 reports
- Haemoglobin decreased: 243 reports
- Haemorrhage (bleeding): 115 reports
- Hair loss: 114 reports
- Headache (pain in head): 626 reports
- Head injury: 114 reports
- Hepatosplenic t-cell lymphoma (neoplasm comprising medium-sized cytotoxic t-cells that show a significant sinusoidal infiltration in the liver, spleen, and bone marrow): 174 reports
- Hepatotoxicity (chemical-driven liver damage): 146 reports
- Herpes zoster: 155 reports
- High blood pressure: 280 reports
- Hyperbilirubinaemia (excess of bilirubin in the blood): 136 reports
- Hyperglycemia (high blood sugar): 118 reports
- Hypersensitivity: 170 reports
- Hypertriglyceridaemia (excess of triglycerides in the blood): 141 reports
- Hypoaesthesia (reduced sense of touch or sensation): 143 reports
- Hypotension (abnormally low blood pressure): 389 reports
- Infection: 212 reports
- Infusion related reaction: 161 reports
- Injection site erythema (redness at injection site): 115 reports
- Injection site pain: 346 reports
- Insomnia (sleeplessness): 108 reports
- Intestinal obstruction: 159 reports
- Itching: 179 reports
- Joint pain: 430 reports
- Leukopenia (less number of white blood cells in blood): 240 reports
- Lymph follicular hypertrophy (an increase in the size of the lymph node follicles): 106 reports
- Malaise (a feeling of general discomfort or uneasiness): 326 reports
- Mucosal inflammation (infection of mucous membrane): 197 reports
- Multi-organ failure (multisystem organ failure): 110 reports
- Muscle aches (muscle pain): 170 reports
- Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 149 reports
- Nasopharyngitis (inflammation of the nasopharynx): 137 reports
- Nausea (feeling of having an urge to vomit): 761 reports
- Nausea and vomiting: 707 reports
- Neuropathy peripheral (surface nerve damage): 180 reports
- Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system): 130 reports
- Neutrophil count decreased (less than normal number of neutrophil a type of blood cell): 177 reports
- Nosebleed (bleeding from nose): 121 reports
- Oedema peripheral (superficial swelling): 101 reports
- Oesophageal candidiasis (fungal infection of oesophagus): 128 reports
- Oral herpes (viral infection of mouth): 115 reports
- Oropharyngeal pain: 133 reports
- Pain: 316 reports
- Pain in extremity: 270 reports
- Pancreatitis (inflammation of pancreas): 334 reports
- Pancreatitis acute (sudden inflammation of pancreas): 133 reports
- Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 395 reports
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 156 reports
- Parainfluenzae virus infection: 230 reports
- Pleural effusion (water on the lungs): 138 reports
- Pneumatosis intestinalis (air or gas in an intestine): 129 reports
- Pneumonia: 562 reports
- Pseudomonal sepsis (pseudomonas infections are diseases caused by a bacterium from the genus pseudomonas): 171 reports
- Rashes (redness): 462 reports
- Rectal haemorrhage (bleeding from anus): 139 reports
- Renal impairment (severely reduced kidney function): 103 reports
- Respiratory acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 171 reports
- Respiratory distress (difficulty in breathing): 128 reports
- Rhinovirus infection: 170 reports
- Seizures (abnormal excessive or synchronous neuronal activity in the brain): 177 reports
- Sepsis (a severe blood infection that can lead to organ failure and death): 487 reports
- Septic shock (shock due to blood infection): 166 reports
- Sinusitis (inflammation of sinus): 167 reports
- Small intestinal obstruction (blockage in small intestine): 115 reports
- Speech impairment (adult) (inability to speak (adult)): 112 reports
- Staphylococcal infection (an infection with staphylococcus bacteria): 122 reports
- Stomatitis (inflammation of mucous membrane of mouth): 165 reports
- Stress and anxiety: 190 reports
- Thrombocytopenia (decrease of platelets in blood): 597 reports
- Ulcerative colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 297 reports
- Upper respiratory tract infection: 160 reports
- Urinary tract infection: 258 reports
- Urticaria (rash of round, red welts on the skin that itch intensely): 107 reports
- Venoocclusive liver disease (small veins in the liver are obstructed): 192 reports
- Venous thrombosis (blood clot (thrombus) that forms within a vein): 110 reports
- Viral infection: 300 reports
- Weakness: 471 reports
- Weight decreased: 324 reports
- Weight increased: 234 reports
- White blood cell count decreased: 228 reports
All Mercaptopurine side effects from A to Z:
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With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
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