Mercaptopurine side effects by duration, gender and age - a phase IV clinical study of FDA data

Summary:

Side effects are reported by people who take Mercaptopurine. Common side effects include febrile neutropenia among females and febrile neutropenia among males.

The phase IV clinical study is created by eHealthMe based on 17,728 reports from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

With medical big data and AI algorithms, eHealthMe enables everyone to run phase IV clinical trial to detect adverse drug outcomes and monitor effectiveness. Our original studies have been referenced on 600+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Most recently, phase IV clinial trails for COVID 19 vaccines have been added, check here.

On Jul, 04, 2022

17,728 people who take Mercaptopurine and have side effects are studied.

What is Mercaptopurine?

Mercaptopurine has active ingredients of mercaptopurine. It is often used in crohn's disease. eHealthMe is studying from 17,982 Mercaptopurine users for its effectiveness, alternative drugs and more.

Number of Mercaptopurine reports submitted per year:

* Approximation only. Some reports may have incomplete information.

Do you take Mercaptopurine?

Personalize this study to your gender and age

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

How the study uses the data?

The study is based on mercaptopurine (the active ingredients of Mercaptopurine) and Mercaptopurine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered.

Related studies

Alternative drugs to, pros and cons of Mercaptopurine:

Mercaptopurine (17,982 reports)

Common Mercaptopurine side effects:

Abdominal distension: 156 reports
Abdominal pain: 692 reports
Abdominal pain upper: 159 reports
Acute kidney failure: 109 reports
Acute lymphocytic leukaemia recurrent (cancer in which the bone marrow makes too many lymphocytes-recurrent): 135 reports
Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 186 reports
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 578 reports
Alanine aminotransferase increased: 286 reports
Anaemia (lack of blood): 452 reports
Anaphylaxis (serious allergic reaction that is rapid in onset and may cause death): 127 reports
Appetite - decreased (decreased appetite occurs when you have a reduced desire to eat): 196 reports
Arrhythmias (irregular heartbeat): 209 reports
Aseptic necrosis (the death of bone tissue due to a lack of blood supply): 174 reports
Aspartate aminotransferase increased: 180 reports
Back pain: 259 reports
Bacterial infection: 407 reports
Blood bilirubin increased: 166 reports
Blood pressure fluctuation: 129 reports
Bone marrow failure: 227 reports
Breathing difficulty: 399 reports
Bronchopulmonary aspergillosis (lung disorder caused by aspergillus fungi): 195 reports
Cellulitis (infection under the skin): 218 reports
Chest pain: 237 reports
Chills (felling of cold): 196 reports
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection): 286 reports
Colitis (inflammation of colon): 239 reports
Constipation: 235 reports
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 125 reports
Cough: 310 reports
Crohn's disease (condition that causes inflammation of the gastrointestinal tract): 906 reports
Cytomegalovirus chorioretinitis (infection of choroid and retina of the eye from virus): 162 reports
Cytomegalovirus infection: 109 reports
Cytomegalovirus viraemia (cytomegalo virus in blood stream): 137 reports
Death: 326 reports
Dehydration (dryness resulting from the removal of water): 195 reports
Depression: 111 reports
Diarrhea: 762 reports
Dizziness: 293 reports
Drowsiness: 127 reports
Drug hypersensitivity: 179 reports
Drug ineffective: 925 reports
Drug intolerance (drug sensitivity): 130 reports
Enteritis (inflammation of the small intestine): 152 reports
Enterobacter infection (infection caused by bacteria of the family enterobacteriaceae): 134 reports
Fall: 124 reports
Fatigue (feeling of tiredness): 670 reports
Febrile bone marrow aplasia (bone marrow greatly decreases or stops production of blood cells): 242 reports
Febrile neutropenia (fever with reduced white blood cells): 1,401 reports
Fever: 1,229 reports
Fungal infection: 206 reports
Gait disturbance: 118 reports
Haematochezia (passage of stools containing blood): 134 reports
Haematotoxicity (toxins that destroy red blood cells): 241 reports
Haemoglobin decreased: 243 reports
Haemorrhage (bleeding): 115 reports
Hair loss: 114 reports
Headache (pain in head): 626 reports
Head injury: 114 reports
Hepatosplenic t-cell lymphoma (neoplasm comprising medium-sized cytotoxic t-cells that show a significant sinusoidal infiltration in the liver, spleen, and bone marrow): 174 reports
Hepatotoxicity (chemical-driven liver damage): 146 reports
Herpes zoster: 155 reports
High blood pressure: 280 reports
Hyperbilirubinaemia (excess of bilirubin in the blood): 136 reports
Hyperglycemia (high blood sugar): 118 reports
Hypersensitivity: 170 reports
Hypertriglyceridaemia (excess of triglycerides in the blood): 141 reports
Hypoaesthesia (reduced sense of touch or sensation): 143 reports
Hypotension (abnormally low blood pressure): 389 reports
Infection: 212 reports
Infusion related reaction: 161 reports
Injection site erythema (redness at injection site): 115 reports
Injection site pain: 346 reports
Insomnia (sleeplessness): 108 reports
Intestinal obstruction: 159 reports
Itching: 179 reports
Joint pain: 430 reports
Leukopenia (less number of white blood cells in blood): 240 reports
Lymph follicular hypertrophy (an increase in the size of the lymph node follicles): 106 reports
Malaise (a feeling of general discomfort or uneasiness): 326 reports
Mucosal inflammation (infection of mucous membrane): 197 reports
Multi-organ failure (multisystem organ failure): 110 reports
Muscle aches (muscle pain): 170 reports
Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 149 reports
Nasopharyngitis (inflammation of the nasopharynx): 137 reports
Nausea (feeling of having an urge to vomit): 761 reports
Nausea and vomiting: 707 reports
Neuropathy peripheral (surface nerve damage): 180 reports
Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system): 130 reports
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell): 177 reports
Nosebleed (bleeding from nose): 121 reports
Oedema peripheral (superficial swelling): 101 reports
Oesophageal candidiasis (fungal infection of oesophagus): 128 reports
Oral herpes (viral infection of mouth): 115 reports
Oropharyngeal pain: 133 reports
Pain: 316 reports
Pain in extremity: 270 reports
Pancreatitis (inflammation of pancreas): 334 reports
Pancreatitis acute (sudden inflammation of pancreas): 133 reports
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 395 reports
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 156 reports
Parainfluenzae virus infection: 230 reports
Pleural effusion (water on the lungs): 138 reports
Pneumatosis intestinalis (air or gas in an intestine): 129 reports
Pneumonia: 562 reports
Pseudomonal sepsis (pseudomonas infections are diseases caused by a bacterium from the genus pseudomonas): 171 reports
Rashes (redness): 462 reports
Rectal haemorrhage (bleeding from anus): 139 reports
Renal impairment (severely reduced kidney function): 103 reports
Respiratory acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 171 reports
Respiratory distress (difficulty in breathing): 128 reports
Rhinovirus infection: 170 reports
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 177 reports
Sepsis (a severe blood infection that can lead to organ failure and death): 487 reports
Septic shock (shock due to blood infection): 166 reports
Sinusitis (inflammation of sinus): 167 reports
Small intestinal obstruction (blockage in small intestine): 115 reports
Speech impairment (adult) (inability to speak (adult)): 112 reports
Staphylococcal infection (an infection with staphylococcus bacteria): 122 reports
Stomatitis (inflammation of mucous membrane of mouth): 165 reports
Stress and anxiety: 190 reports
Thrombocytopenia (decrease of platelets in blood): 597 reports
Ulcerative colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 297 reports
Upper respiratory tract infection: 160 reports
Urinary tract infection: 258 reports
Urticaria (rash of round, red welts on the skin that itch intensely): 107 reports
Venoocclusive liver disease (small veins in the liver are obstructed): 192 reports
Venous thrombosis (blood clot (thrombus) that forms within a vein): 110 reports
Viral infection: 300 reports
Weakness: 471 reports
Weight decreased: 324 reports
Weight increased: 234 reports
White blood cell count decreased: 228 reports

All Mercaptopurine side effects from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

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