Suboxone side effects - from FDA reports


In this review, we analyze Suboxone side effects by the time on the drug, gender and age of the people who have side effects while taking Suboxone. The review is based on 18,624 people who have side effects while taking the drug from FDA, and is updated regularly.

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Suboxone

Suboxone has active ingredients of buprenorphine hydrochloride; naloxone hydrochloride. It is often used in opiate withdrawal. (latest outcomes from Suboxone 20,686 users)


On Jan, 17, 2019

18,624 people who take Suboxone are studied.


Number of reports submitted per year:

Suboxone side effects.

Most common side effects over time *:

< 1 month:
  • Accidental exposure
  • Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
  • Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  • Swollen tongue (swelling of tongue)
  • Drug exposure during pregnancy
  • Headache (pain in head)
  • Vomiting
  • Substance abuse
  • Somnolence (a state of near-sleep, a strong desire for sleep)
  • Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
1 - 6 months:
  • Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
  • Drug exposure during pregnancy
  • Vomiting
  • Maternal exposure during pregnancy (use of substance during pregnancy)
  • Drug withdrawal syndrome neonatal (prenatal nas is caused by discontinuation of drugs taken by the pregnant mother)
  • Premature baby
  • Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
  • Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  • Tremor (trembling or shaking movements in one or more parts of your body)
  • Low birth weight baby
6 - 12 months:
  • Drug exposure during pregnancy
  • Premature baby
  • Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
  • Vomiting
  • Weight decreased
  • Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
  • Drug withdrawal syndrome neonatal (prenatal nas is caused by discontinuation of drugs taken by the pregnant mother)
  • Maternal exposure during pregnancy (use of substance during pregnancy)
  • Abortion spontaneous (naturally occurring miscarriage)
  • Pain
1 - 2 years:
  • Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
  • Vomiting
  • Drug exposure during pregnancy
  • Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
  • Pain
  • Substance abuse
  • Pregnancy
  • Agitation (state of anxiety or nervous excitement)
  • Headache (pain in head)
  • Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
2 - 5 years:
  • Vomiting
  • Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
  • Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)
  • Maternal exposure during pregnancy (use of substance during pregnancy)
  • Substance abuse
  • Death
  • Pneumonia
  • Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)
  • Weight decreased
  • Abortion spontaneous (naturally occurring miscarriage)
5 - 10 years:
  • Leukopenia (less number of white blood cells in blood)
  • Pain
  • Aggression
  • Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  • Malaise (a feeling of general discomfort or uneasiness)
  • Migraine (headache)
  • Pneumonia
  • Substance abuse
  • Urticaria (rash of round, red welts on the skin that itch intensely)
  • Vomiting
10+ years:
  • Depression
  • Limb injury
  • Thinking abnormal
  • Vomiting
  • Yawning (simultaneous inhalation of air and stretching of the eardrums, followed by exhalation of breath)
  • Muscle rupture (tear in muscle)
  • Pain
  • Pneumonia
  • Pulmonary fibrosis (formation or development of excess fibrous connective tissue (fibrosis) in the lungs)
  • Road traffic accident
not specified:
  • Vomiting
  • Substance abuse
  • Suicidal ideation
  • Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  • Pain
  • Death
  • Weight decreased
  • Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
  • Therapeutic response unexpected
  • Maternal exposure during pregnancy (use of substance during pregnancy)

Most common side effects by gender *:

female:
  • Vomiting
  • Drug exposure during pregnancy
  • Substance abuse
  • Maternal exposure during pregnancy (use of substance during pregnancy)
  • Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  • Abortion spontaneous (naturally occurring miscarriage)
  • Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
  • Pain
  • Suicidal ideation
  • Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
male:
  • Substance abuse
  • Vomiting
  • Tremor (trembling or shaking movements in one or more parts of your body)
  • Overdose
  • Road traffic accident
  • Anxiety
  • Suicidal ideation
  • Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  • Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
  • Death

Most common side effects by age *:

0-1:
  • Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
  • Premature baby
  • Low birth weight baby
  • Jaundice neonatal (yellowing of skin in neonate)
  • Vomiting
  • Drug withdrawal syndrome neonatal (prenatal nas is caused by discontinuation of drugs taken by the pregnant mother)
  • Drug exposure during pregnancy
  • Accidental exposure
  • Respiratory disorder neonatal (disease of respiratory organs in a month old baby)
  • Neonatal respiratory distress syndrome (a serious medical condition where a newborn baby's lungs cannot provide their body with enough oxygen)
2-9:
  • Cardiac arrest
  • Constipation
  • Accidental exposure
  • Somnolence (a state of near-sleep, a strong desire for sleep)
  • Vomiting
  • Accidental drug intake by child
  • Drug exposure during pregnancy
  • Respiratory rate decreased (less breathing rate/min)
  • Accidental overdose
  • Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
10-19:
  • Death
  • Substance abuse
  • Vomiting
  • Overdose
  • Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  • Loss of consciousness
  • Suicidal ideation
  • Depression
  • Drug exposure during pregnancy
  • Pre-eclampsia (high blood pressure and significant amounts of protein in the urine of a pregnant woman)
20-29:
  • Vomiting
  • Substance abuse
  • Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  • Drug exposure during pregnancy
  • Suicidal ideation
  • Maternal exposure during pregnancy (use of substance during pregnancy)
  • Abortion spontaneous (naturally occurring miscarriage)
  • Nausea (feeling of having an urge to vomit)
  • Weight decreased
  • Overdose
30-39:
  • Vomiting
  • Substance abuse
  • Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  • Maternal exposure during pregnancy (use of substance during pregnancy)
  • Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
  • Pain
  • Nausea (feeling of having an urge to vomit)
  • Abortion spontaneous (naturally occurring miscarriage)
  • Suicidal ideation
  • Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)
40-49:
  • Vomiting
  • Substance abuse
  • Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  • Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
  • Suicidal ideation
  • Pain
  • Anxiety
  • Tremor (trembling or shaking movements in one or more parts of your body)
  • Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)
  • Nausea (feeling of having an urge to vomit)
50-59:
  • Vomiting
  • Anxiety
  • Substance abuse
  • Suicidal ideation
  • Depression
  • Somnolence (a state of near-sleep, a strong desire for sleep)
  • Weight decreased
  • Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  • Pain
  • Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
60+:
  • Vomiting
  • Weight increased
  • Pain
  • Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
  • Tremor (trembling or shaking movements in one or more parts of your body)
  • Suicidal ideation
  • Nausea (feeling of having an urge to vomit)
  • Somnolence (a state of near-sleep, a strong desire for sleep)
  • Substance abuse
  • Insomnia (sleeplessness)

* Approximation only. Some reports may have incomplete information.

FDA reports used in this study

You are not alone:

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All Suboxone side effects from A to Z

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On eHealthMe, Suboxone (buprenorphine hydrochloride; naloxone hydrochloride) is often used to treat drug dependence. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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