Valtrex side effects by duration, gender and age - a phase IV clinical study of FDA data

Summary:

Side effects are reported by people who take Valtrex. Common side effects include drug ineffective among females and drug ineffective among males.

The phase IV clinical study is created by eHealthMe based on 32,406 reports from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

With medical big data and AI algorithms, eHealthMe enables everyone to run phase IV clinical trial to detect adverse drug outcomes and monitor effectiveness. Our original studies have been referenced on 600+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Most recently, phase IV clinial trails for COVID 19 vaccines have been added, check here.

On May, 08, 2022

32,406 people who take Valtrex and have side effects are studied.

What is Valtrex?

Valtrex has active ingredients of valacyclovir hydrochloride. It is often used in genital herpes. eHealthMe is studying from 34,234 Valtrex users for its effectiveness, alternative drugs and more.

Number of Valtrex reports submitted per year:

* Approximation only. Some reports may have incomplete information.

Do you take Valtrex?

Personalize this study to your gender and age

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

How the study uses the data?

The study is based on valacyclovir hydrochloride (the active ingredients of Valtrex) and Valtrex (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered.

Related studies

Alternative drugs to, pros and cons of Valtrex:

Valtrex (34,234 reports)

Common Valtrex side effects:

Abasia (inability to walk): 159 reports
Abdominal discomfort: 340 reports
Abdominal distension: 293 reports
Abdominal pain: 773 reports
Abdominal pain upper: 562 reports
Abnormal behavior: 215 reports
Acne (skin problems that cause pimples): 123 reports
Acute kidney failure: 649 reports
Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 105 reports
Adverse drug reaction: 159 reports
Adverse event: 115 reports
Aggression: 129 reports
Agitation (state of anxiety or nervous excitement): 533 reports
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 556 reports
Alanine aminotransferase increased: 345 reports
Altered state of consciousness (altered state of mind): 827 reports
Anaemia (lack of blood): 796 reports
Anhedonia (inability to experience pleasure from activities usually found enjoyable): 305 reports
Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight): 291 reports
Appetite - decreased (decreased appetite occurs when you have a reduced desire to eat): 877 reports
Arrhythmias (irregular heartbeat): 307 reports
Arthritis (form of joint disorder that involves inflammation of one or more joints): 199 reports
Arthropathy: 139 reports
Ascites (accumulation of fluid in the abdominal cavity): 115 reports
Aseptic necrosis (the death of bone tissue due to a lack of blood supply): 216 reports
Aspartate aminotransferase increased: 309 reports
Asthma: 282 reports
Atelectasis (partial or complete collapse of the lung): 180 reports
Atrial fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 340 reports
Back pain: 851 reports
Balance disorder: 258 reports
Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills): 103 reports
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure): 189 reports
Blood alkaline phosphatase increased: 168 reports
Blood bilirubin increased: 169 reports
Blood creatinine increased: 779 reports
Blood glucose increased: 251 reports
Blood lactate dehydrogenase increased: 192 reports
Blood sodium decreased: 103 reports
Blood urea increased: 494 reports
Bone density decreased: 101 reports
Bone disorder: 325 reports
Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries): 120 reports
Bone marrow failure: 120 reports
Bone pain: 258 reports
Bradycardia (abnormally slow heart action): 105 reports
Breathing difficulty: 1,300 reports
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 456 reports
Burning sensation: 213 reports
Cardiac arrest: 130 reports
Cardiac disorder: 177 reports
Cardiac failure: 103 reports
Cardiac failure congestive: 238 reports
Cataract (clouding of the lens inside the eye): 179 reports
Cellulitis (infection under the skin): 336 reports
Cerebral infarction (less blood supply to brain resulting tissue damage): 128 reports
Chest pain: 1,019 reports
Chills (felling of cold): 436 reports
Cholecystitis chronic (long lasting infection of gallbladder): 161 reports
Chronic kidney disease: 265 reports
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe): 177 reports
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving): 125 reports
Colitis (inflammation of colon): 105 reports
Condition: 378 reports
Confusion: 428 reports
Confusional state: 600 reports
Constipation: 750 reports
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 209 reports
Cough: 748 reports
C-reactive protein increased: 214 reports
Crohn's disease (condition that causes inflammation of the gastrointestinal tract): 108 reports
Cytomegalovirus infection: 108 reports
Death: 569 reports
Decreased interest: 139 reports
Deep venous thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 449 reports
Dehydration (dryness resulting from the removal of water): 653 reports
Delirium (wild excitement): 499 reports
Delusion (a false belief or opinion): 108 reports
Depressed level of consciousness: 771 reports
Depression: 869 reports
Diabetes: 191 reports
Diarrhea: 1,769 reports
Diplopia (double vision): 129 reports
Disability: 117 reports
Discomfort: 160 reports
Disease progression: 244 reports
Disturbance in attention: 124 reports
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall): 121 reports
Dizziness: 1,818 reports
Drowsiness: 709 reports
Drug effect decreased: 102 reports
Drug exposure during pregnancy: 269 reports
Drug hypersensitivity: 234 reports
Drug ineffective: 2,077 reports
Drug intolerance (drug sensitivity): 198 reports
Drug toxicity: 106 reports
Dry eyes (lack of adequate tears): 132 reports
Dry mouth: 257 reports
Dry skin: 201 reports
Dyskinesia (abnormality or impairment of voluntary movement): 220 reports
Dyslalia (inability to articulate comprehensible speech): 220 reports
Dyspnea exertional: 176 reports
Dysstasia (difficulty in standing): 147 reports
Ear pain: 104 reports
Eating disorder: 136 reports
Emotional distress: 523 reports
Encephalopathy (functioning of the brain is affected by some agent or condition): 553 reports
Enlarged heart: 108 reports
Eosinophilia (eosinophil count in the peripheral blood exceeds): 107 reports
Erythema multiforme (a type of hypersensitivity reaction): 191 reports
Eye pain: 174 reports
Fainting (loss of consciousness and postural tone): 298 reports
Fall: 887 reports
Fatigue (feeling of tiredness): 2,267 reports
Febrile neutropenia (fever with reduced white blood cells): 686 reports
Feeling hot: 134 reports
Femur fracture: 114 reports
Fever: 1,830 reports
Fibromyalgia (a long-term condition which causes pain all over the body): 181 reports
Flatulence (flatus expelled through the anus): 162 reports
Fluid retention (an abnormal accumulation of fluid in the blood): 124 reports
Foot fracture: 102 reports
Fungal infection: 135 reports
Gait disturbance: 827 reports
Gallbladder disorder: 149 reports
Gallstones (stone formation by bile component): 191 reports
Gamma-glutamyltransferase increased: 101 reports
Gastric ulcer (stomach ulcer): 107 reports
Gastritis (inflammation of stomach): 139 reports
Gastroesophageal reflux disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 364 reports
Gastrointestinal disorder (functional problems of gastrointestinal tract): 145 reports
Gastrointestinal haemorrhage (bleeding gastrointestinal tract): 151 reports
General physical health deterioration (weak health status): 335 reports
Genital herpes (herpes infection of genital): 123 reports
Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 155 reports
Haematocrit decreased: 192 reports
Haematuria (presence of blood in urine): 161 reports
Haemoglobin decreased: 494 reports
Haemorrhage (bleeding): 168 reports
Haemorrhoids (a swollen vein or group of veins in the region of the anus): 187 reports
Hair loss: 438 reports
Hallucinations (sensations that appear real but are created by your mind): 573 reports
Hallucination, visual (seeing things that aren't there): 174 reports
Headache (pain in head): 1,912 reports
Head injury: 428 reports
Heart attack: 244 reports
Heart palpitations (feelings or sensations that your heart is pounding or racing): 349 reports
Heart rate decreased: 148 reports
Heart rate increased: 229 reports
Heart rate irregular: 110 reports
Hepatic enzyme increased: 216 reports
Herpes simplex (herpes simplex is a common viral infection): 321 reports
Herpes virus infection: 329 reports
Herpes zoster: 900 reports
Hiatal hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm): 148 reports
High blood cholesterol: 231 reports
High blood pressure: 1,001 reports
Hoarseness or changing voice: 230 reports
Hospitalisation: 127 reports
Hot flush (sudden feelings of heat): 186 reports
Hyperglycemia (high blood sugar): 126 reports
Hyperhidrosis (abnormally increased sweating): 322 reports
Hyperkalemia (damage to or disease of the kidney): 208 reports
Hypersensitivity: 405 reports
Hypoaesthesia (reduced sense of touch or sensation): 641 reports
Hypokalemia (low potassium): 274 reports
Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 204 reports
Hypophagia (reduced food intake): 152 reports
Hypotension (abnormally low blood pressure): 740 reports
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 101 reports
Ill-defined disorder: 239 reports
Impaired healing: 159 reports
Indigestion: 324 reports
Infection: 430 reports
Inflammation: 147 reports
Influenza like illness: 233 reports
Infusion related reaction: 202 reports
Injection site pain: 204 reports
Injury: 542 reports
Insomnia (sleeplessness): 772 reports
Intervertebral disc degeneration (spinal disc degeneration): 106 reports
Intervertebral disc protrusion (spinal disc protrusion): 265 reports
Irritability: 136 reports
Itching: 610 reports
Jaundice - yellow skin (a yellowish pigmentation of the skin): 105 reports
Joint pain: 1,052 reports
Joint swelling: 261 reports
Kidney stones: 165 reports
Leukopenia (less number of white blood cells in blood): 222 reports
Liver disorder (liver diseases): 166 reports
Loss of consciousness: 350 reports
Low tissue oxygen: 139 reports
Lung disorder (lung disease): 114 reports
Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung): 135 reports
Lymph follicular hypertrophy (an increase in the size of the lymph node follicles): 269 reports
Lymphocyte count decreased: 133 reports
Malaise (a feeling of general discomfort or uneasiness): 1,209 reports
Malignant neoplasm progression (cancer tumour came back): 151 reports
Memory loss: 487 reports
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 196 reports
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation): 187 reports
Metastases to liver (cancer spreads to liver): 104 reports
Middle insomnia (difficulty returning to sleep after awakening either in the middle of the night): 103 reports
Migraine (headache): 344 reports
Mitral valve incompetence (inefficient heart valve): 116 reports
Mobility decreased (ability to move is reduced): 146 reports
Mood swings (an extreme or rapid change in mood): 127 reports
Mouth ulcers: 167 reports
Mucosal inflammation (infection of mucous membrane): 155 reports
Multi-organ failure (multisystem organ failure): 125 reports
Multiple myeloma (cancer of the plasma cells): 398 reports
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 138 reports
Muscle aches (muscle pain): 462 reports
Muscle spasms (muscle contraction): 595 reports
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 249 reports
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 149 reports
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 153 reports
Nasopharyngitis (inflammation of the nasopharynx): 487 reports
Nausea (feeling of having an urge to vomit): 2,652 reports
Nausea and vomiting: 1,605 reports
Neck pain: 272 reports
Neoplasm malignant (cancer tumour): 139 reports
Nervousness: 133 reports
Nervous system disorder (a general class of medical conditions affecting the nervous system): 367 reports
Neuralgia (pain in one or more nerves): 141 reports
Neuropathy peripheral (surface nerve damage): 550 reports
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell): 275 reports
Night sweats (sweating in night): 167 reports
Nosebleed (bleeding from nose): 211 reports
Oedema (fluid collection in tissue): 224 reports
Oedema peripheral (superficial swelling): 557 reports
Oral candidiasis (fungal infection of mouth): 101 reports
Oral herpes (viral infection of mouth): 323 reports
Oral pain: 112 reports
Oropharyngeal pain: 340 reports
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 284 reports
Osteomyelitis (infection of bone): 236 reports
Osteonecrosis of jaw (death of bone of jaw): 309 reports
Osteopenia (a condition where bone mineral density is lower than normal): 174 reports
Osteoporosis (bones weak and more likely to break): 302 reports
Overdose: 453 reports
Oxygen saturation decreased: 135 reports
Pain: 1,942 reports
Pain in extremity: 809 reports
Pain in jaw: 232 reports
Pancreatitis (inflammation of pancreas): 123 reports
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 401 reports
Panic disorder: 121 reports
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 560 reports
Pericardial effusion (fluid around the heart): 110 reports
Peripheral swelling: 279 reports
Pleural effusion (water on the lungs): 338 reports
Pneumonia: 1,365 reports
Pollakiuria (abnormally frequent passage of relatively small quantities or urine): 132 reports
Productive cough: 140 reports
Psoriasis (immune-mediated disease that affects the skin): 109 reports
Psychiatric symptom: 151 reports
Pulmonary embolism (blockage of the main artery of the lung): 409 reports
Pulmonary oedema (fluid accumulation in the lungs): 184 reports
Rash erythematous (redness of the skin): 105 reports
Rashes (redness): 1,683 reports
Rash pruritic (redness with itching): 174 reports
Rectal haemorrhage (bleeding from anus): 118 reports
Red blood cell count decreased: 202 reports
Renal disorder (kidney disease): 352 reports
Renal failure acute (rapid kidney dysfunction): 1,169 reports
Renal impairment (severely reduced kidney function): 568 reports
Respiratory acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 251 reports
Respiratory distress (difficulty in breathing): 114 reports
Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints): 261 reports
Road traffic accident: 144 reports
Scar: 134 reports
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 112 reports
Sepsis (a severe blood infection that can lead to organ failure and death): 521 reports
Septic shock (shock due to blood infection): 171 reports
Sinus disorder (disease of sinus): 148 reports
Sinusitis (inflammation of sinus): 507 reports
Sinusitis - chronic: 125 reports
Skin blushing/flushing (a sudden reddening of the face, neck): 193 reports
Skin discoloration: 106 reports
Skin disorder (skin disease): 103 reports
Skin exfoliation (removal of the oldest dead skin cells): 121 reports
Skin ulcer: 108 reports
Sleep apnea syndrome: 149 reports
Sleep disorder: 148 reports
Speech disorder: 510 reports
Speech impairment (adult) (inability to speak (adult)): 900 reports
Spinal compression fracture (fracture due to spinal compression on bone): 103 reports
Spinal osteoarthritis (joint cartilage loss in spine): 214 reports
Staphylococcal infection (an infection with staphylococcus bacteria): 163 reports
Stomatitis (inflammation of mucous membrane of mouth): 319 reports
Stress and anxiety: 1,501 reports
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 233 reports
Suicidal ideation: 216 reports
Surgery: 118 reports
Swallowing difficulty: 330 reports
Swelling: 228 reports
Swelling face: 202 reports
Taste - impaired: 189 reports
The flu (the flu is caused by an influenza virus): 285 reports
Therapeutic response decreased (less preventive response): 121 reports
Therapeutic response unexpected: 191 reports
Thrombocytopenia (decrease of platelets in blood): 1,303 reports
Thrombosis (formation of a blood clot inside a blood vessel): 221 reports
Tinnitus (a ringing in the ears): 167 reports
Tooth abscess (pus formation in tooth): 107 reports
Tooth extraction: 132 reports
Toxic encephalopathy (a degenerative neurologic disorder caused by exposure to toxic substances): 275 reports
Tremor (trembling or shaking movements in one or more parts of your body): 464 reports
Tumor: 118 reports
Type 2 diabetes: 102 reports
Upper respiratory tract infection: 281 reports
Urinary incontinence (inability to control the flow of urine and involuntary urination): 125 reports
Urinary retention (the inability to completely or partially empty the bladder): 245 reports
Urinary tract infection: 605 reports
Urination - painful: 268 reports
Urine output decreased: 169 reports
Urticaria (rash of round, red welts on the skin that itch intensely): 328 reports
Viral infection: 113 reports
Vision blurred: 393 reports
Visual acuity reduced (reduced clearness of vision): 136 reports
Visual impairment: 215 reports
Weakness: 1,614 reports
Weight decreased: 802 reports
Weight increased: 593 reports
Wheezing (a high-pitched whistling sound made while you breath): 184 reports
White blood cell count decreased: 644 reports
White blood cell count increased: 207 reports

All Valtrex side effects from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

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