Zanaflex side effects by duration, gender and age - a phase IV clinical study of FDA data

Summary:

Side effects are reported by people who take Zanaflex. Common side effects include drug ineffective among females and drug ineffective among males.

The phase IV clinical study is created by eHealthMe based on 14,778 reports from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

With medical big data and AI algorithms, eHealthMe enables everyone to run phase IV clinical trial to detect adverse drug outcomes and monitor effectiveness. Our original studies have been referenced on 600+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Most recently, phase IV clinial trails for COVID 19 vaccines have been added, check here.

On May, 15, 2022

14,778 people who take Zanaflex and have side effects are studied.

What is Zanaflex?

Zanaflex has active ingredients of tizanidine hydrochloride. It is often used in muscle spasms. eHealthMe is studying from 15,853 Zanaflex users for its effectiveness, alternative drugs and more.

Number of Zanaflex reports submitted per year:

* Approximation only. Some reports may have incomplete information.

Do you take Zanaflex?

Personalize this study to your gender and age

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

How the study uses the data?

The study is based on tizanidine hydrochloride (the active ingredients of Zanaflex) and Zanaflex (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered.

Related studies

Alternative drugs to, pros and cons of Zanaflex:

Zanaflex (15,853 reports)

Common Zanaflex side effects:

Abasia (inability to walk): 118 reports
Abdominal discomfort: 201 reports
Abdominal distension: 151 reports
Abdominal pain: 390 reports
Abdominal pain upper: 297 reports
Acute kidney failure: 282 reports
Agitation (state of anxiety or nervous excitement): 175 reports
Anaemia (lack of blood): 260 reports
Anhedonia (inability to experience pleasure from activities usually found enjoyable): 102 reports
Appetite - decreased (decreased appetite occurs when you have a reduced desire to eat): 263 reports
Arrhythmias (irregular heartbeat): 139 reports
Arthritis (form of joint disorder that involves inflammation of one or more joints): 213 reports
Arthropathy: 134 reports
Asthma: 202 reports
Back pain: 825 reports
Balance disorder: 281 reports
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure): 115 reports
Blood glucose increased: 183 reports
Blood potassium decreased: 105 reports
Bone disorder: 104 reports
Bone pain: 118 reports
Breathing difficulty: 809 reports
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 305 reports
Burning sensation: 166 reports
Cardiac disorder: 123 reports
Cardiac failure congestive: 176 reports
Cellulitis (infection under the skin): 177 reports
Chest pain: 651 reports
Chills (felling of cold): 338 reports
Chronic kidney disease: 243 reports
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe): 163 reports
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving): 113 reports
Condition: 440 reports
Confusion: 150 reports
Confusional state: 333 reports
Constipation: 553 reports
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 304 reports
Coronary heart disease (narrowing or blockage of the coronary arteries): 103 reports
Cough: 357 reports
Death: 185 reports
Deep venous thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 165 reports
Dehydration (dryness resulting from the removal of water): 338 reports
Depression: 948 reports
Diabetes: 141 reports
Diarrhea: 720 reports
Disturbance in attention: 122 reports
Dizziness: 940 reports
Drowsiness: 483 reports
Drug abuse and dependence: 165 reports
Drug dependence: 297 reports
Drug effect decreased: 110 reports
Drug hypersensitivity: 390 reports
Drug ineffective: 1,021 reports
Drug intolerance (drug sensitivity): 108 reports
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation): 356 reports
Dry mouth: 200 reports
Dry skin: 121 reports
Ear pain: 123 reports
Emotional distress: 255 reports
Fainting (loss of consciousness and postural tone): 223 reports
Fall: 1,104 reports
Fatigue (feeling of tiredness): 1,418 reports
Fever: 541 reports
Fibromyalgia (a long-term condition which causes pain all over the body): 230 reports
Gait disturbance: 601 reports
Gastric ulcer (stomach ulcer): 102 reports
Gastroesophageal reflux disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 329 reports
Gastrointestinal haemorrhage (bleeding gastrointestinal tract): 102 reports
General physical health deterioration (weak health status): 103 reports
Haemoglobin decreased: 110 reports
Hair loss: 229 reports
Hallucinations (sensations that appear real but are created by your mind): 217 reports
Headache (pain in head): 1,259 reports
Head injury: 380 reports
Heart attack: 320 reports
Heart palpitations (feelings or sensations that your heart is pounding or racing): 198 reports
Heart rate decreased: 113 reports
Heart rate increased: 169 reports
Herpes zoster: 103 reports
High blood cholesterol: 221 reports
High blood pressure: 843 reports
Hoarseness or changing voice: 111 reports
Hyperhidrosis (abnormally increased sweating): 312 reports
Hypersensitivity: 205 reports
Hypoaesthesia (reduced sense of touch or sensation): 640 reports
Hypotension (abnormally low blood pressure): 651 reports
Impaired healing: 116 reports
Indigestion: 211 reports
Infection: 170 reports
Influenza like illness: 345 reports
Injection site erythema (redness at injection site): 102 reports
Injection site pain: 264 reports
Injury: 209 reports
Insomnia (sleeplessness): 691 reports
Intervertebral disc degeneration (spinal disc degeneration): 184 reports
Intervertebral disc protrusion (spinal disc protrusion): 236 reports
Irritability: 134 reports
Itching: 421 reports
Joint pain: 747 reports
Joint swelling: 199 reports
Kidney stones: 130 reports
Loss of consciousness: 390 reports
Malaise (a feeling of general discomfort or uneasiness): 520 reports
Memory loss: 575 reports
Migraine (headache): 381 reports
Mobility decreased (ability to move is reduced): 141 reports
Mood swings (an extreme or rapid change in mood): 102 reports
Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 476 reports
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 461 reports
Muscle aches (muscle pain): 346 reports
Muscle spasms (muscle contraction): 695 reports
Muscle spasticity (tight or stiff muscles and an inability to control those muscles): 128 reports
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 199 reports
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 219 reports
Nasopharyngitis (inflammation of the nasopharynx): 210 reports
Nausea (feeling of having an urge to vomit): 1,365 reports
Nausea and vomiting: 820 reports
Neck pain: 349 reports
Neuralgia (pain in one or more nerves): 122 reports
Neuropathy peripheral (surface nerve damage): 149 reports
Night sweats (sweating in night): 118 reports
Oedema (fluid collection in tissue): 158 reports
Oedema peripheral (superficial swelling): 361 reports
Oral pain: 102 reports
Oropharyngeal pain: 125 reports
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 244 reports
Osteonecrosis of jaw (death of bone of jaw): 107 reports
Osteoporosis (bones weak and more likely to break): 146 reports
Overdose: 189 reports
Pain: 1,584 reports
Pain in extremity: 655 reports
Panic disorder: 159 reports
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 391 reports
Peripheral swelling: 160 reports
Pneumonia: 528 reports
Pollakiuria (abnormally frequent passage of relatively small quantities or urine): 115 reports
Pulmonary embolism (blockage of the main artery of the lung): 181 reports
Rashes (redness): 591 reports
Rectal haemorrhage (bleeding from anus): 106 reports
Renal failure acute (rapid kidney dysfunction): 113 reports
Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints): 156 reports
Road traffic accident: 192 reports
Sedation: 188 reports
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 141 reports
Sepsis (a severe blood infection that can lead to organ failure and death): 197 reports
Sinusitis (inflammation of sinus): 338 reports
Skin blushing/flushing (a sudden reddening of the face, neck): 204 reports
Skin disorder (skin disease): 103 reports
Sleep apnea syndrome: 165 reports
Sleep disorder: 147 reports
Speech disorder: 166 reports
Speech impairment (adult) (inability to speak (adult)): 241 reports
Spinal osteoarthritis (joint cartilage loss in spine): 101 reports
Staphylococcal infection (an infection with staphylococcus bacteria): 104 reports
Stress and anxiety: 925 reports
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 253 reports
Suicidal ideation: 248 reports
Suicide attempt: 112 reports
Swallowing difficulty: 330 reports
Swelling: 146 reports
The flu (the flu is caused by an influenza virus): 174 reports
Therapeutic response unexpected: 106 reports
Thrombocytopenia (decrease of platelets in blood): 125 reports
Thrombosis (formation of a blood clot inside a blood vessel): 165 reports
Tremor (trembling or shaking movements in one or more parts of your body): 471 reports
Upper respiratory tract infection: 114 reports
Urinary incontinence (inability to control the flow of urine and involuntary urination): 187 reports
Urinary tract infection: 651 reports
Urination - painful: 128 reports
Urticaria (rash of round, red welts on the skin that itch intensely): 129 reports
Vision blurred: 360 reports
Visual impairment: 237 reports
Weakness: 1,221 reports
Weight decreased: 585 reports
Weight increased: 410 reports
Wheezing (a high-pitched whistling sound made while you breath): 137 reports
White blood cell count decreased: 133 reports
Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance): 127 reports

All Zanaflex side effects from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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