Zetia side effects - from FDA reports


In this review, we analyze Zetia side effects by the time on the drug, gender and age of the people who have side effects while taking Zetia. The review is based on 38,028 people who have side effects while taking the drug from FDA, and is updated regularly.

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Zetia

Zetia has active ingredients of ezetimibe. It is often used in high blood cholesterol. (latest outcomes from Zetia 38,963 users)


On Feb, 18, 2019

38,028 people who take Zetia are studied.


Number of reports submitted per year:

Zetia side effects.

Most common side effects over time *:

< 1 month:
  • Myalgia (muscle pain)
  • Pain in extremity
  • Vomiting
  • Urticaria (rash of round, red welts on the skin that itch intensely)
  • Rash
  • Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
  • Nausea (feeling of having an urge to vomit)
  • Muscle cramp (painful sensation caused by muscle contraction)
  • Pain
  • Swelling face
1 - 6 months:
  • Vomiting
  • Aspartate aminotransferase increased
  • Pain
  • Liver disorder (liver diseases)
  • Alopecia (absence of hair from areas of the body)
  • Weight decreased
  • Liver function test abnormal
  • Nausea (feeling of having an urge to vomit)
  • Rash
  • Urticaria (rash of round, red welts on the skin that itch intensely)
6 - 12 months:
  • Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
  • Myalgia (muscle pain)
  • Pain in extremity
  • Blood creatine phosphokinase increased
  • Weight decreased
  • Abdominal pain
  • Pancreatitis (inflammation of pancreas)
  • Hepatic enzyme increased
  • Myositis (inflammation of the muscles)
  • Liver function test abnormal
1 - 2 years:
  • Myalgia (muscle pain)
  • Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
  • Pain in extremity
  • Blood creatine phosphokinase increased
  • Hepatic enzyme increased
  • Muscle spasms (muscle contraction)
  • Drug ineffective
  • Muscular weakness (muscle weakness)
  • Pancreatitis (inflammation of pancreas)
  • Autoimmune hepatitis
2 - 5 years:
  • Myalgia (muscle pain)
  • Pain in extremity
  • Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
  • Pain
  • Swollen tongue (swelling of tongue)
  • Wrist fracture
  • Blood creatine phosphokinase increased
  • Muscle spasms (muscle contraction)
  • Pneumonia
  • Syncope (loss of consciousness with an inability to maintain postural tone)
5 - 10 years:
  • Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  • Weight decreased
  • Myositis (inflammation of the muscles)
  • Bladder cancer
  • Myalgia (muscle pain)
  • Type 2 diabetes mellitus
  • Angina pectoris (chest pain due to ischemia of the heart muscle)
  • Bile duct cancer
  • Bile duct obstruction (blockage in the tubes that carry bile from the liver to the gallbladder)
  • Contusion (a type of hematoma of tissue in which capillaries)
10+ years:
  • Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  • Anaemia (lack of blood)
  • Hypoacusis (loss of hearing)
  • Injection site injury
  • Ischaemic stroke (stroke; caused by an interruption in the flow of blood to the brain)
  • Low density lipoprotein increased (cholesterol increased in blood)
  • Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
  • Muscle spasms (muscle contraction)
  • Nerve injury
  • Neuropathy peripheral (surface nerve damage)
not specified:
  • Myalgia (muscle pain)
  • Weight decreased
  • Drug ineffective
  • Vomiting
  • Pain in extremity
  • Nausea (feeling of having an urge to vomit)
  • Weight increased
  • Pain
  • Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  • Rash

Most common side effects by gender *:

female:
  • Myalgia (muscle pain)
  • Pain in extremity
  • Vomiting
  • Weight decreased
  • Nausea (feeling of having an urge to vomit)
  • Weight increased
  • Drug ineffective
  • Pain
  • Pruritus (severe itching of the skin)
  • Rash
male:
  • Myalgia (muscle pain)
  • Weight decreased
  • Pain
  • Nausea (feeling of having an urge to vomit)
  • Weight increased
  • Death
  • Pruritus (severe itching of the skin)
  • Pancreatitis (inflammation of pancreas)
  • Liver function test abnormal
  • Dizziness

Most common side effects by age *:

0-1:
  • Hypoaesthesia (reduced sense of touch or sensation)
  • Abdominal pain upper
  • Alopecia (absence of hair from areas of the body)
  • Drug administration error
  • Pain in extremity
  • Pulmonary embolism (blockage of the main artery of the lung)
  • Syncope (loss of consciousness with an inability to maintain postural tone)
  • Tonic convulsion (the person will quickly lose consciousness and the skeletal muscles will suddenly tense, often causing the extremities to be pulled towards the body or rigidly pushed away from it)
  • Type 2 diabetes mellitus
  • Viral pharyngitis (inflammation of the throat or pharynx caused by viral infection)
2-9:
  • General physical condition
  • Pharyngeal oedema (abnormal accumulation of fluid in the cavities and intercellular spaces of the pharyngeal)
  • Posterior reversible encephalopathy syndrome (posterior reversible encephalopathy syndrome (pres), also known as reversible posterior leukoencephalopathy syndrome (rpls), is a syndrome characterized by headache, confusion, seizures and visual loss)
  • Vomiting
  • Alopecia (absence of hair from areas of the body)
  • Drug ineffective
  • Gallbladder disorder
  • Headache (pain in head)
  • Muscle cramp (painful sensation caused by muscle contraction)
  • Muscular weakness (muscle weakness)
10-19:
  • General physical condition
  • Blood thyroid stimulating hormone increased
  • High density lipoprotein decreased
  • Pain in extremity
  • Vomiting
  • Myalgia (muscle pain)
  • Takayasu's arteritis (an inflammation of the aorta -- the artery that carries blood from the heart to the rest of the body)
  • Transaminases increased
  • Urinary tract infection
  • Varicella
20-29:
  • Anaemia (lack of blood)
  • Anti-insulin antibody positive
  • Blood creatine phosphokinase increased
  • Febrile neutropenia (fever with reduced white blood cells)
  • Headache (pain in head)
  • Peripheral coldness
  • Urticaria (rash of round, red welts on the skin that itch intensely)
  • Abdominal pain upper
  • Cardiac disorder
  • Emotional distress
30-39:
  • Myalgia (muscle pain)
  • Vomiting
  • Alanine aminotransferase increased
  • Urticaria (rash of round, red welts on the skin that itch intensely)
  • Blood creatine phosphokinase increased
  • Drug ineffective
  • Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
  • Nausea (feeling of having an urge to vomit)
  • Weight increased
  • Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
40-49:
  • Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
  • Myalgia (muscle pain)
  • Vomiting
  • Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  • Blood creatine phosphokinase increased
  • Weight decreased
  • Nausea (feeling of having an urge to vomit)
  • Pain
  • Rash
  • Weight increased
50-59:
  • Weight decreased
  • Myalgia (muscle pain)
  • Vomiting
  • Weight increased
  • Nausea (feeling of having an urge to vomit)
  • Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  • Pain in extremity
  • Drug ineffective
  • Rash
  • Headache (pain in head)
60+:
  • Myalgia (muscle pain)
  • Weight decreased
  • Pain in extremity
  • Vomiting
  • Nausea (feeling of having an urge to vomit)
  • Drug ineffective
  • Weight increased
  • Pain
  • Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  • Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)

* Approximation only. Some reports may have incomplete information.

FDA reports used in this study

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On eHealthMe, Zetia (ezetimibe) is often used to treat high blood cholesterol. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

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