Abraxane and Acute coronary syndrome - a phase IV clinical study of FDA data

Summary:

Acute coronary syndrome is found among people who take Abraxane, especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months.

The phase IV clinical study analyzes which people take Abraxane and have Acute coronary syndrome. It is created by eHealthMe based on reports of 17,415 people who have side effects when taking Abraxane from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.



On Mar, 27, 2023

17,415 people reported to have side effects when taking Abraxane.
Among them, 6 people (0.03%) have Acute coronary syndrome.


What is Abraxane?

Abraxane has active ingredients of paclitaxel. It is often used in breast cancer metastatic. eHealthMe is studying from 17,487 Abraxane users for its effectiveness, alternative drugs and more.

What is Acute coronary syndrome?

Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood) is found to be associated with 1,511 drugs and 952 conditions by eHealthMe.

Number of Abraxane and Acute coronary syndrome reports submitted per year:

Could Abraxane cause Acute coronary syndrome?

Time on Abraxane when people have Acute coronary syndrome *:

  • < 1 month: 25 %
  • 1 - 6 months: 50 %
  • 6 - 12 months: 25 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Acute coronary syndrome when taking Abraxane *:

  • female: 60 %
  • male: 40 %

Age of people who have Acute coronary syndrome when taking Abraxane *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 40 %
  • 60+: 60 %

Common drugs people take besides Abraxane *:

  1. Oxycodone: 2 people, 33.33%
  2. Gemcitabine: 2 people, 33.33%
  3. Zopiclone: 1 person, 16.67%
  4. Sertraline: 1 person, 16.67%
  5. Paracetamol: 1 person, 16.67%
  6. Ondansetron: 1 person, 16.67%
  7. Novorapid: 1 person, 16.67%
  8. Metformin: 1 person, 16.67%
  9. Levemir: 1 person, 16.67%
  10. Lasix: 1 person, 16.67%

Common side effects people have besides Acute coronary syndrome *:

  1. Neutrophil Count Abnormal (abnormal number of neutrophil a type of blood cell): 1 person, 16.67%
  2. Lung Infection: 1 person, 16.67%
  3. Haemolytic Uraemic Syndrome (blood clotting disease caused by e. coli infection, birth control pills, pneumonia, medications, and more): 1 person, 16.67%
  4. Gastrointestinal Haemorrhage (bleeding gastrointestinal tract): 1 person, 16.67%
  5. Acute Left Ventricular Failure (heart attack): 1 person, 16.67%

Common conditions people have *:

  1. Pancreatic Carcinoma (pancreatic cancer): 2 people, 33.33%
  2. Pancreatic Carcinoma Metastatic (pancreatic cancer- metastatic): 1 person, 16.67%
  3. Lung Neoplasm Malignant (cancer tumour of lung): 1 person, 16.67%
  4. Hypopharyngeal Cancer: 1 person, 16.67%
  5. Haemoglobin Decreased: 1 person, 16.67%

* Approximation only. Some reports may have incomplete information.

Do you take Abraxane and have Acute coronary syndrome?

Check whether Acute coronary syndrome is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.



Related studies

How severe was Acute coronary syndrome and when was it recovered:

Expand to all the drugs that have ingredients of paclitaxel:

Alternative drugs to, pros and cons of Abraxane:

Common Abraxane side effects:

Browse all side effects of Abraxane:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Acute coronary syndrome treatments and more:

COVID vaccines that are related to Acute coronary syndrome:

Common drugs associated with Acute coronary syndrome:

All the drugs that are associated with Acute coronary syndrome:

Common conditions associated with Acute coronary syndrome:

All the conditions that are associated with Acute coronary syndrome:

How the study uses the data?

The study uses data from the FDA. It is based on paclitaxel (the active ingredients of Abraxane) and Abraxane (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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