Accutane and Chronic fatigue syndrome - a phase IV clinical study of FDA data

Summary:

We study 32,747 people who have side effects when taking Accutane. Chronic fatigue syndrome is found, especially among people who are female, 20-29 old, have been taking the drug for 1 - 6 months, also take Ortho tri-cyclen and have Stress and anxiety.

The phase IV clinical study analyzes which people take Accutane and have Chronic fatigue syndrome. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Nov, 07, 2023

32,747 people reported to have side effects when taking Accutane.
Among them, 328 people (1.0%) have Chronic fatigue syndrome.

What is Accutane?

Accutane has active ingredients of isotretinoin. It is used in acne. Currently, eHealthMe is studying from 34,514 Accutane users.

What is Chronic fatigue syndrome?

Chronic fatigue syndrome (disorder that causes extreme fatigue) is found to be associated with 894 drugs and 844 conditions by eHealthMe. Currently, we are studying 5,043 people who have Chronic fatigue syndrome.

Number of Accutane and Chronic fatigue syndrome reports submitted per year:

Could Accutane cause Chronic fatigue syndrome?

* Approximation only. Some reports may have incomplete information.

Do you take Accutane and have Chronic fatigue syndrome?

Check whether Chronic fatigue syndrome is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Ersoy MA, Ersoy HT, "Manic symptoms associated with isotretinoin and methylphenidate combination: a case report", Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology, 2014 Sep .

Related studies

Accutane side effects by duration, gender and age:

Accutane side effects (34,514 reports)

Chronic fatigue syndrome treatments and more:

Chronic fatigue syndrome (5,043 reports)

Common drugs associated with Chronic fatigue syndrome:

Vioxx: 341 reports
Accutane: 328 reports
Zoloft: 109 reports

All the drugs that are associated with Chronic fatigue syndrome:

Chronic fatigue syndrome (894 drugs)

Common conditions associated with Chronic fatigue syndrome:

Acne: 178 reports
Pain: 120 reports
Depression: 110 reports
High blood pressure: 102 reports

All the conditions that are associated with Chronic fatigue syndrome:

Chronic fatigue syndrome (844 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on isotretinoin (the active ingredients of Accutane) and Accutane (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.