Accutane and Depression - a phase IV clinical study of FDA data
Summary:
Depression is found among people who take Accutane, especially for people who are female, 10-19 old, have been taking the drug for 1 - 6 months.
The phase IV clinical study analyzes which people take Accutane and have Depression. It is created by eHealthMe based on reports of 32,000 people who have side effects when taking Accutane from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
32,000 people reported to have side effects when taking Accutane.
Among them, 8,074 people (25.23%) have Depression.
What is Accutane?
Accutane has active ingredients of isotretinoin. It is often used in acne. eHealthMe is studying from 33,753 Accutane users for its effectiveness, alternative drugs and more.
What is Depression?
Depression is found to be associated with 4,230 drugs and 4,026 conditions by eHealthMe.
Number of Accutane and Depression reports submitted per year:
Time on Accutane when people have Depression *:
Gender of people who have Depression when taking Accutane*:
Age of people who have Depression when taking Accutane *:
Common drugs people take besides Accutane *:
Common side effects people have besides Depression *:
Common conditions people have *:
* Approximation only. Some reports may have incomplete information.
Do you take Accutane and have Depression?
Check whether Depression is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- Pang, T., & Gudi, A., "Chest pain following the use of fluvoxamine in depression", Proceedings of Singapore Healthcare, 2018 Jan .
- Ersoy MA, Ersoy HT, "Manic symptoms associated with isotretinoin and methylphenidate combination: a case report", Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology, 2014 Sep .
Related studies
How severe was Depression and when was it recovered:
Expand to all the drugs that have ingredients of isotretinoin:
- Depression and drugs with ingredients of isotretinoin (10,634 reports)
Alternative drugs to, pros and cons of Accutane:
- Accutane (33,753 reports)
Common Accutane side effects:
- Depression: 9,826 reports
- Ulcerative colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 9,190 reports
- Crohn's disease (condition that causes inflammation of the gastrointestinal tract): 7,519 reports
- Stress and anxiety: 5,193 reports
- Irritable bowel syndrome: 4,848 reports
Browse all side effects of Accutane:
a b c d e f g h i j k l m n o p q r s t u v w x y zDepression treatments and more:
- Depression (599,520 reports)
COVID vaccines that are related to Depression:
- Depression in Moderna COVID Vaccine
- Depression in Pfizer BioNTech Covid Vaccine
- Depression in Johnson and Johnson Covid Vaccine
Common drugs associated with Depression:
- Chantix: 11,911 reports
- Prednisone: 11,218 reports
- Oxycontin: 9,692 reports
- Aspirin: 9,458 reports
- Zoloft: 8,834 reports
- Fosamax: 8,381 reports
- Accutane: 8,074 reports
- Vioxx: 7,964 reports
- Gabapentin: 7,920 reports
- Cymbalta: 7,851 reports
All the drugs that are associated with Depression:
- Depression (4,230 drugs)
Common conditions associated with Depression:
- Multiple sclerosis: 20,384 reports
- Pain: 12,961 reports
- High blood pressure: 10,315 reports
- Rheumatoid arthritis: 10,067 reports
All the conditions that are associated with Depression:
- Depression (4,026 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on isotretinoin (the active ingredients of Accutane) and Accutane (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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