Accutane and Irritable bowel syndrome - a phase IV clinical study of FDA data
Summary:
Irritable bowel syndrome is found among people who take Accutane, especially for people who are female, 20-29 old, have been taking the drug for 1 - 6 months.
The phase IV clinical study analyzes which people take Accutane and have Irritable bowel syndrome. It is created by eHealthMe based on reports of 32,000 people who have side effects when taking Accutane from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
32,000 people reported to have side effects when taking Accutane.
Among them, 4,848 people (15.15%) have Irritable bowel syndrome.
What is Accutane?
Accutane has active ingredients of isotretinoin. It is often used in acne. eHealthMe is studying from 33,719 Accutane users for its effectiveness, alternative drugs and more.
What is Irritable bowel syndrome?
Irritable bowel syndrome is found to be associated with 2,640 drugs and 2,048 conditions by eHealthMe.
Number of Accutane and Irritable bowel syndrome reports submitted per year:

Time on Accutane when people have Irritable bowel syndrome *:
Gender of people who have Irritable bowel syndrome when taking Accutane*:
Age of people who have Irritable bowel syndrome when taking Accutane *:
Common drugs people take besides Accutane *:
Common side effects people have besides Irritable bowel syndrome *:
Common conditions people have *:
* Approximation only. Some reports may have incomplete information.
Do you take Accutane and have Irritable bowel syndrome?
Check whether Irritable bowel syndrome is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- Ersoy MA, Ersoy HT, "Manic symptoms associated with isotretinoin and methylphenidate combination: a case report", Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology, 2014 Sep .
Related studies
How severe was Irritable bowel syndrome and when was it recovered:
Expand to all the drugs that have ingredients of isotretinoin:
Alternative drugs to, pros and cons of Accutane:
- Accutane (33,719 reports)
Common Accutane side effects:
- Depression: 9,826 reports
- Ulcerative colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 9,190 reports
- Crohn's disease (condition that causes inflammation of the gastrointestinal tract): 7,519 reports
- Stress and anxiety: 5,193 reports
- Irritable bowel syndrome: 4,848 reports
Browse all side effects of Accutane:
a b c d e f g h i j k l m n o p q r s t u v w x y zIrritable bowel syndrome treatments and more:
- Irritable bowel syndrome (43,387 reports)
COVID vaccines that are related to Irritable bowel syndrome:
- Irritable bowel syndrome in Moderna COVID Vaccine
- Irritable bowel syndrome in Pfizer BioNTech Covid Vaccine
- Irritable bowel syndrome in Johnson and Johnson Covid Vaccine
Common drugs associated with Irritable bowel syndrome:
- Accutane: 4,848 reports
- Prednisone: 2,927 reports
- Methotrexate: 2,728 reports
- Enbrel: 2,492 reports
- Profen: 2,356 reports
- Ibuprofen: 2,355 reports
- Ibu: 2,355 reports
- Humira: 2,258 reports
- Cimzia: 2,159 reports
- Simponi: 2,131 reports
All the drugs that are associated with Irritable bowel syndrome:
- Irritable bowel syndrome (2,640 drugs)
Common conditions associated with Irritable bowel syndrome:
- Acne: 3,224 reports
- Rheumatoid arthritis: 3,051 reports
- High blood pressure: 1,869 reports
- Osteoporosis: 1,043 reports
- Pain: 876 reports
- Multiple sclerosis: 850 reports
- Depression: 778 reports
All the conditions that are associated with Irritable bowel syndrome:
- Irritable bowel syndrome (2,048 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on isotretinoin (the active ingredients of Accutane) and Accutane (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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