Acetaminophen and codeine phosphate and Cellulitis - a phase IV clinical study of FDA data


Cellulitis is found among people who take Acetaminophen and codeine phosphate, especially for people who are male, 60+ old, have been taking the drug for 2 - 5 years.

The phase IV clinical study analyzes which people take Acetaminophen and codeine phosphate and have Cellulitis. It is created by eHealthMe based on reports of 2,908 people who have side effects when taking Acetaminophen and codeine phosphate from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Sep, 03, 2023

2,908 people reported to have side effects when taking Acetaminophen and codeine phosphate.
Among them, 29 people (1.0%) have Cellulitis.

What is Acetaminophen and codeine phosphate?

Acetaminophen and codeine phosphate has active ingredients of acetaminophen; codeine phosphate. It is often used in pain. eHealthMe is studying from 3,220 Acetaminophen and codeine phosphate users for its effectiveness, alternative drugs and more.

What is Cellulitis?

Cellulitis (infection under the skin) is found to be associated with 3,159 drugs and 2,284 conditions by eHealthMe.

Number of Acetaminophen and codeine phosphate and Cellulitis reports submitted per year:

Could Acetaminophen and codeine phosphate cause Cellulitis?

Time on Acetaminophen and codeine phosphate when people have Cellulitis *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 100 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Cellulitis when taking Acetaminophen and codeine phosphate *:

  • female: 50 %
  • male: 50 %

Age of people who have Cellulitis when taking Acetaminophen and codeine phosphate *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 4.17 %
  • 30-39: 4.17 %
  • 40-49: 8.33 %
  • 50-59: 4.17 %
  • 60+: 79.17 %

Common drugs people take besides Acetaminophen and codeine phosphate *:

  1. Aspirin: 11 people, 37.93%
  2. Omeprazole: 10 people, 34.48%
  3. Lisinopril: 8 people, 27.59%
  4. Simvastatin: 8 people, 27.59%
  5. Ipratropium Bromide: 7 people, 24.14%
  6. Isosorbide Mononitrate: 7 people, 24.14%
  7. Zocor: 6 people, 20.69%
  8. Humira: 6 people, 20.69%
  9. Lactulose: 5 people, 17.24%
  10. Nitroglycerin: 5 people, 17.24%

Common side effects people have besides Cellulitis *:

  1. Rashes (redness): 5 people, 17.24%
  2. Head Injury: 5 people, 17.24%
  3. Oedema Peripheral (superficial swelling): 5 people, 17.24%
  4. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 4 people, 13.79%
  5. Chest Pain: 4 people, 13.79%
  6. Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 4 people, 13.79%
  7. Gastric Ulcer (stomach ulcer): 3 people, 10.34%
  8. Skin Discoloration: 3 people, 10.34%
  9. Skin Ulcer: 3 people, 10.34%
  10. Joint Swelling: 3 people, 10.34%

Common conditions people have *:

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 5 people, 17.24%
  2. High Blood Pressure: 5 people, 17.24%
  3. Hypercalcaemia (elevated calcium (ca+) level in the blood): 4 people, 13.79%
  4. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 4 people, 13.79%
  5. Constipation: 4 people, 13.79%
  6. Depression: 4 people, 13.79%
  7. Psoriasis (immune-mediated disease that affects the skin): 3 people, 10.34%
  8. Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve): 2 people, 6.90%
  9. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 2 people, 6.90%
  10. Chest Pain: 2 people, 6.90%

* Approximation only. Some reports may have incomplete information.

Do you take Acetaminophen and codeine phosphate and have Cellulitis?

Check whether Cellulitis is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Related studies

How severe was Cellulitis and when was it recovered:

Expand to all the drugs that have ingredients of acetaminophen; codeine phosphate:

Alternative drugs to, pros and cons of Acetaminophen and codeine phosphate:

Common Acetaminophen and codeine phosphate side effects:

Browse all side effects of Acetaminophen and codeine phosphate:

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Cellulitis treatments and more:

COVID vaccines that are related to Cellulitis:

Common drugs associated with Cellulitis:

All the drugs that are associated with Cellulitis:

Common conditions associated with Cellulitis:

All the conditions that are associated with Cellulitis:

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; codeine phosphate (the active ingredients of Acetaminophen and codeine phosphate) and Acetaminophen and codeine phosphate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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