Acetaminophen and hydrocodone bitartrate and Ear barotrauma - a phase IV clinical study of FDA data
Summary:
Ear barotrauma is found among people who take Acetaminophen and hydrocodone bitartrate, especially for people who are female, 40-49 old.
The phase IV clinical study analyzes which people take Acetaminophen and hydrocodone bitartrate and have Ear barotrauma. It is created by eHealthMe based on reports of 5,944 people who have side effects when taking Acetaminophen and hydrocodone bitartrate from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
5,944 people reported to have side effects when taking Acetaminophen and hydrocodone bitartrate.
Among them, 7 people (0.12%) have Ear barotrauma.
What is Acetaminophen and hydrocodone bitartrate?
Acetaminophen and hydrocodone bitartrate has active ingredients of acetaminophen; hydrocodone bitartrate. It is often used in pain. eHealthMe is studying from 6,079 Acetaminophen and hydrocodone bitartrate users for its effectiveness, alternative drugs and more.
What is Ear barotrauma?
Ear barotrauma (discomfort and possible damage in the ear due to pressure differences between the inside and outside of the eardrum) is found to be associated with 927 drugs and 564 conditions by eHealthMe.
Number of Acetaminophen and hydrocodone bitartrate and Ear barotrauma reports submitted per year:

Gender of people who have Ear barotrauma when taking Acetaminophen and hydrocodone bitartrate *:
- female: 100 %
- male: 0.0 %
Age of people who have Ear barotrauma when taking Acetaminophen and hydrocodone bitartrate *:
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 0.0 %
- 40-49: 85.71 %
- 50-59: 0.0 %
- 60+: 14.29 %
Common drugs people take besides Acetaminophen and hydrocodone bitartrate *:
- Synthroid: 7 people, 100.00%
- Zyrtec: 6 people, 85.71%
- Mobic: 6 people, 85.71%
- Amoxicillin: 6 people, 85.71%
- Aredia: 6 people, 85.71%
- Boniva: 6 people, 85.71%
- Cefadroxil: 6 people, 85.71%
- Celebrex: 6 people, 85.71%
- Chlorhexidine Gluconate: 6 people, 85.71%
- Clotrimazole: 6 people, 85.71%
Common side effects people have besides Ear barotrauma *:
- Intervertebral Disc Degeneration (spinal disc degeneration): 7 people, 100.00%
- Stress And Anxiety: 7 people, 100.00%
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 7 people, 100.00%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 100.00%
- Muscle Aches (muscle pain): 7 people, 100.00%
- Injury: 6 people, 85.71%
- Joint Pain: 6 people, 85.71%
- General Physical Health Deterioration (weak health status): 6 people, 85.71%
- Ear Pain: 6 people, 85.71%
- Dyslipidaemia (abnormal amount of lipids): 6 people, 85.71%
Common conditions people have *:
- Osteoporosis (bones weak and more likely to break): 3 people, 42.86%
- Osteopenia (a condition where bone mineral density is lower than normal): 1 person, 14.29%
- Osteoarthritis (a joint disease caused by cartilage loss in a joint): 1 person, 14.29%
- Oedema (fluid collection in tissue): 1 person, 14.29%
- High Blood Pressure: 1 person, 14.29%
- High Blood Cholesterol: 1 person, 14.29%
* Approximation only. Some reports may have incomplete information.
Do you take Acetaminophen and hydrocodone bitartrate and have Ear barotrauma?
Check whether Ear barotrauma is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
How severe was Ear barotrauma and when was it recovered:
Expand to all the drugs that have ingredients of acetaminophen; hydrocodone bitartrate:
Alternative drugs to, pros and cons of Acetaminophen and hydrocodone bitartrate:
- Acetaminophen and hydrocodone bitartrate (6,079 reports)
Common Acetaminophen and hydrocodone bitartrate side effects:
- Abdominal pain: 189 reports
- Abdominal pain upper: 134 reports
- Anaemia (lack of blood): 281 reports
- Appetite - decreased (decreased appetite occurs when you have a reduced desire to eat): 123 reports
- Aseptic necrosis (the death of bone tissue due to a lack of blood supply): 111 reports
- Atelectasis (partial or complete collapse of the lung): 118 reports
- Atrial fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 103 reports
- Back pain: 322 reports
- Bone disorder: 227 reports
- Breathing difficulty: 328 reports
- Breathing - slowed or stopped: 487 reports
- Cardiac arrest: 525 reports
- Cardiac failure congestive: 133 reports
- Cardio-respiratory arrest (sudden dysfunction of heart and lungs): 462 reports
- Chest pain: 296 reports
- Completed suicide (act of taking one's own life): 1,585 reports
- Confusional state: 123 reports
- Constipation: 208 reports
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 103 reports
- Cough: 112 reports
- Death: 306 reports
- Deep venous thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 166 reports
- Dehydration (dryness resulting from the removal of water): 144 reports
- Dental caries: 126 reports
- Depression: 347 reports
- Diarrhea: 246 reports
- Dizziness: 250 reports
- Drowsiness: 157 reports
- Drug abuse and dependence: 346 reports
- Drug ineffective: 199 reports
- Drug toxicity: 104 reports
- Emotional distress: 192 reports
- Fall: 255 reports
- Fatigue (feeling of tiredness): 306 reports
- Fever: 187 reports
- Gait disturbance: 108 reports
- Gastroesophageal reflux disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 142 reports
- Headache (pain in head): 237 reports
- High blood pressure: 209 reports
- Hyperhidrosis (abnormally increased sweating): 109 reports
- Hypoaesthesia (reduced sense of touch or sensation): 165 reports
- Hypotension (abnormally low blood pressure): 239 reports
- Impaired healing: 141 reports
- Infection: 129 reports
- Injury: 256 reports
- Insomnia (sleeplessness): 229 reports
- Joint pain: 215 reports
- Loss of consciousness: 118 reports
- Malaise (a feeling of general discomfort or uneasiness): 127 reports
- Memory loss: 142 reports
- Multiple drug overdose: 258 reports
- Multiple drug overdose intentional: 106 reports
- Nausea (feeling of having an urge to vomit): 407 reports
- Nausea and vomiting: 316 reports
- Oedema peripheral (superficial swelling): 220 reports
- Osteoarthritis (a joint disease caused by cartilage loss in a joint): 217 reports
- Osteomyelitis (infection of bone): 152 reports
- Osteonecrosis of jaw (death of bone of jaw): 241 reports
- Overdose: 160 reports
- Pain: 554 reports
- Pain in extremity: 211 reports
- Pain in jaw: 180 reports
- Pleural effusion (water on the lungs): 138 reports
- Pneumonia: 234 reports
- Poisoning: 164 reports
- Pulmonary embolism (blockage of the main artery of the lung): 161 reports
- Rashes (redness): 211 reports
- Renal failure acute (rapid kidney dysfunction): 107 reports
- Road traffic accident: 123 reports
- Sinusitis (inflammation of sinus): 127 reports
- Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node): 119 reports
- Spinal osteoarthritis (joint cartilage loss in spine): 116 reports
- Stress and anxiety: 512 reports
- Thrombocytopenia (decrease of platelets in blood): 116 reports
- Tooth abscess (pus formation in tooth): 108 reports
- Tooth disorder (tooth disease): 119 reports
- Tooth extraction: 166 reports
- Urinary tract infection: 108 reports
- Vision blurred: 113 reports
- Weakness: 299 reports
- Weight decreased: 232 reports
Browse all side effects of Acetaminophen and hydrocodone bitartrate:
a b c d e f g h i j k l m n o p q r s t u v w x y zEar barotrauma treatments and more:
- Ear barotrauma (1,366 reports)
COVID vaccines that are related to Ear barotrauma:
- Ear barotrauma in Moderna COVID Vaccine
- Ear barotrauma in Pfizer BioNTech Covid Vaccine
- Ear barotrauma in Johnson and Johnson Covid Vaccine
Common drugs associated with Ear barotrauma:
All the drugs that are associated with Ear barotrauma:
- Ear barotrauma (927 drugs)
Common conditions associated with Ear barotrauma:
- Blood pressure - high: 112 reports
- Blood pressure increased: 112 reports
- Foetal exposure during pregnancy: 217 reports
- Hbp: 112 reports
- High blood pressure: 112 reports
- Htn: 112 reports
- Hypertension: 112 reports
- Hypertension aggravated: 112 reports
- Osteoporosis: 264 reports
- Thin bones: 263 reports
All the conditions that are associated with Ear barotrauma:
- Ear barotrauma (564 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on acetaminophen; hydrocodone bitartrate (the active ingredients of Acetaminophen and hydrocodone bitartrate) and Acetaminophen and hydrocodone bitartrate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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