Acetaminophen and Anger - a phase IV clinical study of FDA data


Anger is found among people who take Acetaminophen, especially for people who are female, 60+ old, have been taking the drug for < 1 month.

The phase IV clinical study analyzes which people take Acetaminophen and have Anger. It is created by eHealthMe based on reports of 75,274 people who have side effects when taking Acetaminophen from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

With medical big data and AI algorithms, eHealthMe enables everyone to run phase IV clinical trial to detect adverse drug outcomes and monitor effectiveness. Our original studies have been referenced on 600+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Most recently, phase IV clinial trails for COVID 19 vaccines have been added, check here.

On Jun, 15, 2022

75,274 people reported to have side effects when taking Acetaminophen.
Among them, 98 people (0.13%) have Anger.

What is Acetaminophen?

Acetaminophen has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 77,127 Acetaminophen users for its effectiveness, alternative drugs and more.

What is Anger?

Anger is found to be associated with 2,089 drugs and 1,560 conditions by eHealthMe.

Number of Acetaminophen and Anger reports submitted per year:

Could Acetaminophen cause Anger?

Time on Acetaminophen when people have Anger *:

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Anger when taking Acetaminophen *:

  • female: 57.73 %
  • male: 42.27 %

Age of people who have Anger when taking Acetaminophen *:

  • 0-1: 0.0 %
  • 2-9: 2.41 %
  • 10-19: 10.84 %
  • 20-29: 2.41 %
  • 30-39: 7.23 %
  • 40-49: 19.28 %
  • 50-59: 28.92 %
  • 60+: 28.92 %

Common drugs people take besides Acetaminophen *:

  1. Ibuprofen: 22 people, 22.45%
  2. Omeprazole: 13 people, 13.27%
  3. Seroquel: 13 people, 13.27%
  4. Chantix: 12 people, 12.24%
  5. Lexapro: 10 people, 10.20%
  6. Naproxen: 10 people, 10.20%
  7. Simvastatin: 10 people, 10.20%
  8. Ativan: 9 people, 9.18%
  9. Dexamethasone: 8 people, 8.16%
  10. Lorazepam: 8 people, 8.16%

Common side effects people have besides Anger *:

  1. Stress And Anxiety: 39 people, 39.80%
  2. Depression: 31 people, 31.63%
  3. Fatigue (feeling of tiredness): 31 people, 31.63%
  4. Aggression: 26 people, 26.53%
  5. Irritability: 24 people, 24.49%
  6. Agitation (state of anxiety or nervous excitement): 23 people, 23.47%
  7. Insomnia (sleeplessness): 23 people, 23.47%
  8. Nausea (feeling of having an urge to vomit): 23 people, 23.47%
  9. Suicidal Ideation: 22 people, 22.45%
  10. Abnormal Behavior: 20 people, 20.41%

Common conditions people have *:

  1. Depression: 20 people, 20.41%
  2. Stress And Anxiety: 15 people, 15.31%
  3. Quit Smoking: 9 people, 9.18%
  4. High Blood Cholesterol: 8 people, 8.16%
  5. Sleep Disorder: 8 people, 8.16%
  6. Post-Traumatic Stress Disorder: 8 people, 8.16%
  7. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 6 people, 6.12%
  8. Barrett's Oesophagus (barrett's oesophagus is a disorder in which the lining of the oesophagus (the tube that carries food from the throat to the stomach) is damaged by stomach acid and changed to a lining similar to that of the stomach): 6 people, 6.12%
  9. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 5 people, 5.10%
  10. Migraine (headache): 5 people, 5.10%

* Approximation only. Some reports may have incomplete information.

Do you take Acetaminophen and have Anger?

Check whether Anger is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

Alternative drugs to, pros and cons of Acetaminophen:

Anger treatments and more:

COVID vaccines that are related to Anger:

How severe was Anger and when was it recovered:

Expand to all the drugs that have ingredients of acetaminophen:

Common drugs associated with Anger:

All the drugs that are associated with Anger:

Common conditions associated with Anger:

All the conditions that are associated with Anger:

  • Anger (1,560 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen (the active ingredients of Acetaminophen) and Acetaminophen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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