Acetaminophen and Colorectal cancer metastatic - a phase IV clinical study of FDA data


Colorectal cancer metastatic is found among people who take Acetaminophen, especially for people who are female, 60+ old.

The phase IV clinical study analyzes which people take Acetaminophen and have Colorectal cancer metastatic. It is created by eHealthMe based on reports of 106,002 people who have side effects when taking Acetaminophen from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Sep, 22, 2022

106,002 people reported to have side effects when taking Acetaminophen.
Among them, 6 people (0.01%) have Colorectal cancer metastatic.

What is Acetaminophen?

Acetaminophen has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 107,871 Acetaminophen users for its effectiveness, alternative drugs and more.

What is Colorectal cancer metastatic?

Colorectal cancer metastatic (cancer of colon and rectal spreads to other parts) is found to be associated with 334 drugs and 178 conditions by eHealthMe.

Number of Acetaminophen and Colorectal cancer metastatic reports submitted per year:

Could Acetaminophen cause Colorectal cancer metastatic?

Gender of people who have Colorectal cancer metastatic when taking Acetaminophen *:

  • female: 66.67 %
  • male: 33.33 %

Age of people who have Colorectal cancer metastatic when taking Acetaminophen *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 16.67 %
  • 50-59: 33.33 %
  • 60+: 50.0 %

Common drugs people take besides Acetaminophen *:

  1. Fluorouracil: 2 people, 33.33%
  2. Hydrochlorothiazide: 2 people, 33.33%
  3. Leucovorin Calcium: 2 people, 33.33%
  4. Warfarin Sodium: 1 person, 16.67%
  5. Hydrocortisone Acetate: 1 person, 16.67%
  6. Avastin: 1 person, 16.67%
  7. Avinza: 1 person, 16.67%
  8. Escitalopram: 1 person, 16.67%
  9. Fentanyl Citrate: 1 person, 16.67%
  10. Folic Acid: 1 person, 16.67%

Common side effects people have besides Colorectal cancer metastatic *:

  1. Malignant Neoplasm Progression (cancer tumour came back): 3 people, 50.00%
  2. Abdominal Pain: 2 people, 33.33%
  3. Blood Alkaline Phosphatase Increased: 2 people, 33.33%
  4. High Blood Pressure: 2 people, 33.33%
  5. Rectal Haemorrhage (bleeding from anus): 2 people, 33.33%
  6. Death: 1 person, 16.67%
  7. Diarrhea: 1 person, 16.67%
  8. Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall): 1 person, 16.67%
  9. Fall: 1 person, 16.67%
  10. Fistula (an abnormal connection or passageway between two): 1 person, 16.67%

Common conditions people have *:

  1. High Blood Cholesterol: 2 people, 33.33%
  2. Urinary Tract Infection: 1 person, 16.67%
  3. Skin Disorder (skin disease): 1 person, 16.67%
  4. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 16.67%
  5. Prostate Cancer: 1 person, 16.67%
  6. Osteoporosis (bones weak and more likely to break): 1 person, 16.67%
  7. Neoplasm Malignant (cancer tumour): 1 person, 16.67%
  8. High Blood Pressure: 1 person, 16.67%
  9. Heart Disease: 1 person, 16.67%
  10. Colon Cancer: 1 person, 16.67%

* Approximation only. Some reports may have incomplete information.

Do you take Acetaminophen and have Colorectal cancer metastatic?

Check whether Colorectal cancer metastatic is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

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Expand to all the drugs that have ingredients of acetaminophen:

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Common Acetaminophen side effects:

Browse all side effects of Acetaminophen:

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Colorectal cancer metastatic treatments and more:

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Common drugs associated with Colorectal cancer metastatic:

All the drugs that are associated with Colorectal cancer metastatic:

Common conditions associated with Colorectal cancer metastatic:

All the conditions that are associated with Colorectal cancer metastatic:

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen (the active ingredients of Acetaminophen) and Acetaminophen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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