Acetazolamide and Pericardial effusion - a phase IV clinical study of FDA data


Pericardial effusion is found among people who take Acetazolamide, especially for people who are female, 60+ old, have been taking the drug for < 1 month.

The phase IV clinical study analyzes which people take Acetazolamide and have Pericardial effusion. It is created by eHealthMe based on reports of 4,756 people who have side effects when taking Acetazolamide from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Oct, 03, 2022

4,756 people reported to have side effects when taking Acetazolamide.
Among them, 24 people (0.5%) have Pericardial effusion.

What is Acetazolamide?

Acetazolamide has active ingredients of acetazolamide. It is often used in pseudotumor cerebri. eHealthMe is studying from 4,962 Acetazolamide users for its effectiveness, alternative drugs and more.

What is Pericardial effusion?

Pericardial effusion (fluid around the heart) is found to be associated with 1,958 drugs and 1,345 conditions by eHealthMe.

Number of Acetazolamide and Pericardial effusion reports submitted per year:

Could Acetazolamide cause Pericardial effusion?

Time on Acetazolamide when people have Pericardial effusion *:

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Pericardial effusion when taking Acetazolamide *:

  • female: 63.64 %
  • male: 36.36 %

Age of people who have Pericardial effusion when taking Acetazolamide *:

  • 0-1: 0.0 %
  • 2-9: 5 %
  • 10-19: 0.0 %
  • 20-29: 15 %
  • 30-39: 0.0 %
  • 40-49: 5 %
  • 50-59: 5 %
  • 60+: 70 %

Common drugs people take besides Acetazolamide *:

  1. Lasix: 11 people, 45.83%
  2. Fludarabine Phosphate: 7 people, 29.17%
  3. Aldactone: 7 people, 29.17%
  4. Cytarabine: 7 people, 29.17%
  5. Hydrocortisone Sodium Succinate: 5 people, 20.83%
  6. Methylprednisolone Sodium Succinate: 5 people, 20.83%
  7. Heparin Sodium: 5 people, 20.83%
  8. Lovenox: 4 people, 16.67%
  9. Granisetron Hydrochloride: 4 people, 16.67%
  10. Seroquel: 4 people, 16.67%

Common side effects people have besides Pericardial effusion *:

  1. High Blood Pressure: 8 people, 33.33%
  2. Headache (pain in head): 8 people, 33.33%
  3. Breathing Difficulty: 7 people, 29.17%
  4. Fatigue (feeling of tiredness): 7 people, 29.17%
  5. Hypotension (abnormally low blood pressure): 6 people, 25.00%
  6. Lung Disorder (lung disease): 6 people, 25.00%
  7. Pleural Effusion (water on the lungs): 6 people, 25.00%
  8. Weakness: 6 people, 25.00%
  9. Tricuspid Valve Incompetence (inefficient heart valve): 5 people, 20.83%
  10. Cardiac Failure Congestive: 5 people, 20.83%

Common conditions people have *:

  1. Insomnia (sleeplessness): 4 people, 16.67%
  2. Constipation: 4 people, 16.67%
  3. Diabetes: 4 people, 16.67%
  4. High Blood Pressure: 2 people, 8.33%
  5. Bone Marrow Conditioning Regimen: 2 people, 8.33%
  6. High Blood Cholesterol: 2 people, 8.33%
  7. Hypotension (abnormally low blood pressure): 2 people, 8.33%
  8. Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 2 people, 8.33%
  9. Pneumocystis Jiroveci Pneumonia (fungal infection of the lungs): 2 people, 8.33%
  10. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Acetazolamide and have Pericardial effusion?

Check whether Pericardial effusion is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

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How severe was Pericardial effusion and when was it recovered:

Expand to all the drugs that have ingredients of acetazolamide:

Alternative drugs to, pros and cons of Acetazolamide:

Common Acetazolamide side effects:

Browse all side effects of Acetazolamide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Pericardial effusion treatments and more:

COVID vaccines that are related to Pericardial effusion:

Common drugs associated with Pericardial effusion:

All the drugs that are associated with Pericardial effusion:

Common conditions associated with Pericardial effusion:

All the conditions that are associated with Pericardial effusion:

How the study uses the data?

The study uses data from the FDA. It is based on acetazolamide (the active ingredients of Acetazolamide) and Acetazolamide (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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