Acitretin and Gastrointestinal disorder - a phase IV clinical study of FDA data

Summary:

Gastrointestinal disorder is found among people who take Acitretin, especially for people who are male, 40-49 old, have been taking the drug for 1 - 2 years.

The phase IV clinical study analyzes which people take Acitretin and have Gastrointestinal disorder. It is created by eHealthMe based on reports of 4,313 people who have side effects when taking Acitretin from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.



On Nov, 16, 2022

4,313 people reported to have side effects when taking Acitretin.
Among them, 49 people (1.14%) have Gastrointestinal disorder.


What is Acitretin?

Acitretin has active ingredients of acitretin. eHealthMe is studying from 4,339 Acitretin users for its effectiveness, alternative drugs and more.

What is Gastrointestinal disorder?

Gastrointestinal disorder (functional problems of gastrointestinal tract) is found to be associated with 2,281 drugs and 1,812 conditions by eHealthMe.

Number of Acitretin and Gastrointestinal disorder reports submitted per year:

Could Acitretin cause Gastrointestinal disorder?

Time on Acitretin when people have Gastrointestinal disorder *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 100 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Gastrointestinal disorder when taking Acitretin *:

  • female: 21.74 %
  • male: 78.26 %

Age of people who have Gastrointestinal disorder when taking Acitretin *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 4.76 %
  • 40-49: 54.76 %
  • 50-59: 7.14 %
  • 60+: 33.33 %

Common drugs people take besides Acitretin *:

  1. Cimzia: 21 people, 42.86%
  2. Methotrexate: 13 people, 26.53%
  3. Cyclosporine: 6 people, 12.24%
  4. Mycophenolate Mofetil: 6 people, 12.24%
  5. Naproxen: 5 people, 10.20%
  6. Sulfasalazine: 5 people, 10.20%
  7. Azathioprine: 5 people, 10.20%
  8. Leflunomide: 5 people, 10.20%
  9. Permethrin: 5 people, 10.20%
  10. Omeprazole Magnesium: 5 people, 10.20%

Common side effects people have besides Gastrointestinal disorder *:

  1. Drug Ineffective: 25 people, 51.02%
  2. Psoriasis (immune-mediated disease that affects the skin): 24 people, 48.98%
  3. Diarrhea: 24 people, 48.98%
  4. Dry Skin: 23 people, 46.94%
  5. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 21 people, 42.86%
  6. Hidradenitis (chronic disease of a type of sweat gland): 21 people, 42.86%
  7. Anal Haemorrhage: 21 people, 42.86%
  8. Arthritis (form of joint disorder that involves inflammation of one or more joints): 6 people, 12.24%
  9. Mycosis Fungoides (lymphocytes (a type of white blood cell) become malignant (cancerous) and affect the skin): 5 people, 10.20%
  10. Malaise (a feeling of general discomfort or uneasiness): 3 people, 6.12%

Common conditions people have *:

  1. Psoriasis (immune-mediated disease that affects the skin): 21 people, 42.86%
  2. Pemphigoid (tense blisters on the skin): 6 people, 12.24%
  3. Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 5 people, 10.20%
  4. Pustular Psoriasis (raised bumps on the skin that are filled with pus): 4 people, 8.16%
  5. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 4 people, 8.16%
  6. Erythrodermic Psoriasis (generalized redness of the skin): 3 people, 6.12%
  7. Seborrhoeic Dermatitis (a common, inflammatory skin condition that causes flaky, white to yellowish scales to form on oily areas such as the scalp): 2 people, 4.08%
  8. Psoriasis - Guttate (skin condition in which small, red, and scaly teardrop-shaped spots appear on the arms, legs, and middle of the body): 2 people, 4.08%
  9. Ankylosing Spondylitis (type of arthritis affecting the spine): 2 people, 4.08%
  10. Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 1 person, 2.04%

* Approximation only. Some reports may have incomplete information.

Do you take Acitretin and have Gastrointestinal disorder?

Check whether Gastrointestinal disorder is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.



Related studies

How severe was Gastrointestinal disorder and when was it recovered:

Expand to all the drugs that have ingredients of acitretin:

Alternative drugs to, pros and cons of Acitretin:

Common Acitretin side effects:

Browse all side effects of Acitretin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Gastrointestinal disorder treatments and more:

COVID vaccines that are related to Gastrointestinal disorder:

Common drugs associated with Gastrointestinal disorder:

All the drugs that are associated with Gastrointestinal disorder:

Common conditions associated with Gastrointestinal disorder:

All the conditions that are associated with Gastrointestinal disorder:

How the study uses the data?

The study uses data from the FDA. It is based on acitretin (the active ingredients of Acitretin) and Acitretin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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