Actemra and Crepitations - a phase IV clinical study of FDA data

Summary:

Crepitations is found among people who take Actemra, especially for people who are female, 40-49 old, have been taking the drug for 1 - 2 years.

The phase IV clinical study analyzes which people take Actemra and have Crepitations. It is created by eHealthMe based on reports of 85,119 people who have side effects when taking Actemra from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Nov, 30, 2022

85,119 people reported to have side effects when taking Actemra.
Among them, 145 people (0.17%) have Crepitations.

What is Actemra?

Actemra has active ingredients of tocilizumab. It is often used in rheumatoid arthritis. eHealthMe is studying from 85,315 Actemra users for its effectiveness, alternative drugs and more.

What is Crepitations?

Crepitations (noises are produced by the rubbing of parts one against the other) is found to be associated with 1,089 drugs and 572 conditions by eHealthMe.

Number of Actemra and Crepitations reports submitted per year:

* Approximation only. Some reports may have incomplete information.

Do you take Actemra and have Crepitations?

Check whether Crepitations is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Crepitations and when was it recovered:

Crepitations in Actemra

Expand to all the drugs that have ingredients of tocilizumab:

Crepitations and drugs with ingredients of tocilizumab

Alternative drugs to, pros and cons of Actemra:

Actemra (85,315 reports)

Common Actemra side effects:

Drug ineffective: 40,430 reports
Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints): 25,436 reports
Pain: 20,065 reports
Joint pain: 16,945 reports
Joint swelling: 15,891 reports
Fatigue (feeling of tiredness): 13,817 reports
Rashes (redness): 13,617 reports

Browse all side effects of Actemra:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Crepitations treatments and more:

Crepitations (4,339 reports)

COVID vaccines that are related to Crepitations:

Common drugs associated with Crepitations:

All the drugs that are associated with Crepitations:

Crepitations (1,089 drugs)

Common conditions associated with Crepitations:

Rheumatoid arthritis: 504 reports
Asthma: 331 reports
High blood pressure: 162 reports
Osteoporosis: 134 reports
Pain: 131 reports

All the conditions that are associated with Crepitations:

Crepitations (572 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on tocilizumab (the active ingredients of Actemra) and Actemra (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.