Actemra and Dupuytren's contracture - a phase IV clinical study of FDA data

Summary:

Dupuytren's contracture is found among people who take Actemra, especially for people who are female, 60+ old.

The phase IV clinical study analyzes which people take Actemra and have Dupuytren's contracture. It is created by eHealthMe based on reports of 72,940 people who have side effects when taking Actemra from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

With medical big data and AI algorithms, eHealthMe enables everyone to run phase IV clinical trial to detect adverse drug outcomes and monitor effectiveness. Our original studies have been referenced on 600+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Most recently, phase IV clinial trails for COVID 19 vaccines have been added, check here.

On Jun, 12, 2022

72,940 people reported to have side effects when taking Actemra.
Among them, 15 people (0.02%) have Dupuytren's contracture.

What is Actemra?

Actemra has active ingredients of tocilizumab. It is often used in rheumatoid arthritis. eHealthMe is studying from 73,125 Actemra users for its effectiveness, alternative drugs and more.

What is Dupuytren's contracture?

Dupuytren's contracture (thickening of the fibrous tissue layer underneath the skin of the palm and fingers) is found to be associated with 435 drugs and 194 conditions by eHealthMe.

Number of Actemra and Dupuytren's contracture reports submitted per year:

Could Actemra cause Dupuytren's contracture?

Gender of people who have Dupuytren's contracture when taking Actemra *:

female: 93.33 %
male: 6.67 %

Age of people who have Dupuytren's contracture when taking Actemra *:

Common drugs people take besides Actemra *:

Common side effects people have besides Dupuytren's contracture *:

Joint Pain: 12 people, 80.00%
Musculoskeletal Stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 12 people, 80.00%
Drug Ineffective: 12 people, 80.00%
Chronic Kidney Disease: 11 people, 73.33%
Headache (pain in head): 11 people, 73.33%
Pain: 10 people, 66.67%
Influenza Like Illness: 10 people, 66.67%
Fever: 10 people, 66.67%
Intervertebral Disc Protrusion (spinal disc protrusion): 10 people, 66.67%
Joint Swelling: 10 people, 66.67%

* Approximation only. Some reports may have incomplete information.

Do you take Actemra and have Dupuytren's contracture?

Check whether Dupuytren's contracture is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

Alternative drugs to, pros and cons of Actemra:

Actemra (73,125 reports)

Dupuytren's contracture treatments and more:

Dupuytren's contracture (2,028 reports)

COVID vaccines that are related to Dupuytren's contracture:

How severe was Dupuytren's contracture and when was it recovered:

Dupuytren's contracture in Actemra

Expand to all the drugs that have ingredients of tocilizumab:

Dupuytren's contracture and drugs with ingredients of tocilizumab (15 reports)

Common drugs associated with Dupuytren's contracture:

Xiaflex: 137 reports

All the drugs that are associated with Dupuytren's contracture:

Dupuytren's contracture (435 drugs)

All the conditions that are associated with Dupuytren's contracture:

Dupuytren's contracture (194 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on tocilizumab (the active ingredients of Actemra) and Actemra (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.