Actemra and Joint swelling - a phase IV clinical study of FDA data
Summary:
We study 85,119 people who have side effects when taking Actemra. Joint swelling is found, especially among people who are female, 40-49 old, have been taking the drug for 2 - 5 years, also take Enbrel and have Pain.
The phase IV clinical study analyzes which people take Actemra and have Joint swelling. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.
What are phase IV trials?
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
85,119 people reported to have side effects when taking Actemra.
Among them, 15,891 people (18.67%) have Joint swelling.
What is Actemra?
Actemra has active ingredients of tocilizumab. It is used in rheumatoid arthritis. Currently, eHealthMe is studying from 97,637 Actemra users.
What is Joint swelling?
Joint swelling is found to be associated with 3,473 drugs and 2,861 conditions by eHealthMe. Currently, we are studying 134,313 people who have Joint swelling.
Number of Actemra and Joint swelling reports submitted per year:

Time on Actemra when people have Joint swelling *:
Gender of people who have Joint swelling when taking Actemra*:
Age of people who have Joint swelling when taking Actemra *:
Common drugs people take besides Actemra *:
Common side effects people have besides Joint swelling *:
Common conditions people have *:
* Approximation only. Some reports may have incomplete information.
Do you take Actemra and have Joint swelling?
Check whether Joint swelling is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
How severe was Joint swelling and when was it recovered:
Expand to all the drugs that have ingredients of tocilizumab:
- Joint swelling and drugs with ingredients of tocilizumab (7,711 reports)
Alternative drugs to, pros and cons of Actemra:
- Actemra (97,637 reports)
Browse all side effects of Actemra:
a b c d e f g h i j k l m n o p q r s t u v w x y zJoint swelling treatments and more:
- Joint swelling (134,313 reports)
Common drugs associated with Joint swelling:
- Methotrexate: 29,058 reports
- Enbrel: 29,056 reports
- Humira: 24,773 reports
- Prednisone: 23,148 reports
- Orencia: 17,226 reports
- Actemra: 15,891 reports
- Xeljanz: 15,442 reports
- Sulfasalazine: 13,386 reports
- Leflunomide: 12,445 reports
- Arava: 12,313 reports
All the drugs that are associated with Joint swelling:
- Joint swelling (3,473 drugs)
Common conditions associated with Joint swelling:
- Rheumatoid arthritis: 43,452 reports
- High blood pressure: 5,948 reports
- Pain: 5,108 reports
- Psoriasis: 4,042 reports
- Osteoporosis: 2,823 reports
All the conditions that are associated with Joint swelling:
- Joint swelling (2,861 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on tocilizumab (the active ingredients of Actemra) and Actemra (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
Recent studies on eHealthMe:
- Tafinlar and Secretion Discharge - 7 seconds ago
- Atenolol and Vitiligo - 10 seconds ago
- Budesonide and Myasthenia Gravis Aggravated - 23 seconds ago
- Tretinoin and Ear Pain - 23 seconds ago
- Guaifenesin and Enlarged Heart - 31 seconds ago
- Sertraline and Cerebral Ventricle Dilatation - 33 seconds ago
- Vitamin C and Hepatic Encephalopathy - 38 seconds ago
- Doxycycline Hyclate and Cyclophosphamide drug interaction - a minute ago
- Levonorgestrel and Tobi Podhaler drug interaction - a minute ago
- Oxycodone and Skin Papilloma - a minute ago