Actigall and Acne - a phase IV clinical study of FDA data


We study 2,060 people who have side effects when taking Actigall. Acne is found, especially among people who are female, , also take Singulair and have Crohn's disease.

The phase IV clinical study analyzes which people take Actigall and have Acne. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Sep, 08, 2023

2,060 people reported to have side effects when taking Actigall.
Among them, 3 people (0.15%) have Acne.

What is Actigall?

Actigall has active ingredients of ursodiol. It is used in gallstones. Currently, eHealthMe is studying from 2,100 Actigall users.

What is Acne?

Acne (skin problems that cause pimples) is found to be associated with 2,620 drugs and 2,214 conditions by eHealthMe. Currently, we are studying 173,296 people who have Acne.

Number of Actigall and Acne reports submitted per year:

Could Actigall cause Acne?

Gender of people who have Acne when taking Actigall *:

  • female: 66.67 %
  • male: 33.33 %

Common drugs people take besides Actigall *:

  1. Singulair: 2 people, 66.67%
  2. Xopenex: 1 person, 33.33%
  3. Klonopin: 1 person, 33.33%
  4. Allegra Allergy: 1 person, 33.33%
  5. Belsomra: 1 person, 33.33%
  6. Colace: 1 person, 33.33%
  7. Creon: 1 person, 33.33%
  8. Effexor: 1 person, 33.33%
  9. Elmiron: 1 person, 33.33%
  10. Epipen: 1 person, 33.33%

Common side effects people have besides Acne *:

  1. Polymenorrhea: 1 person, 33.33%
  2. Pain In Extremity: 1 person, 33.33%
  3. Menstruation Irregular: 1 person, 33.33%
  4. Fatigue (feeling of tiredness): 1 person, 33.33%
  5. Drug Ineffective: 1 person, 33.33%
  6. Cataract (clouding of the lens inside the eye): 1 person, 33.33%
  7. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure): 1 person, 33.33%

Common conditions people have *:

  1. Immunodeficiency Common Variable: 1 person, 33.33%
  2. Cystic Fibrosis (disease of the secretary glands): 1 person, 33.33%
  3. Crohn's Disease (condition that causes inflammation of the gastrointestinal tract): 1 person, 33.33%

* Approximation only. Some reports may have incomplete information.

Do you take Actigall and have Acne?

Check whether Acne is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

Actigall side effects by duration, gender and age:

Acne treatments and more:

  • Acne (173,296 reports)

Common drugs associated with Acne:

All the drugs that are associated with Acne:

  • Acne (2,620 drugs)

Common conditions associated with Acne:

All the conditions that are associated with Acne:

  • Acne (2,214 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on ursodiol (the active ingredients of Actigall) and Actigall (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

Recent studies on eHealthMe: