Actonel and Pain disorder - a phase IV clinical study of FDA data


Pain disorder is reported only by a few people who take Actonel.

The phase IV clinical study analyzes which people take Actonel and have Pain disorder. It is created by eHealthMe based on reports of 28,020 people who have side effects while taking Actonel from the FDA, and is updated regularly.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Jan, 29, 2023

28,020 people reported to have side effects when taking Actonel.
Among them, 1 person (0.0%) has Pain disorder.

What is Actonel?

Actonel has active ingredients of risedronate sodium. It is often used in osteoporosis. eHealthMe is studying from 28,455 Actonel users for its effectiveness, alternative drugs and more.

What is Pain disorder?

Pain disorder is found to be associated with 416 drugs and 246 conditions by eHealthMe.

Number of Actonel and Pain disorder reports submitted per year:

Could Actonel cause Pain disorder?

Gender of people who have Pain disorder when taking Actonel *:

  • female: 100 %
  • male: 0.0 %

Common drugs people take besides Actonel *:

  1. Fosamax: 1 person, 100.00%
  2. Celebrex: 1 person, 100.00%

Common side effects people have besides Pain disorder *:

  1. Wound Dehiscence (a surgical incision reopens either internally or externally): 1 person, 100.00%
  2. Weakness: 1 person, 100.00%
  3. Joint Pain: 1 person, 100.00%
  4. Jaw Fracture: 1 person, 100.00%
  5. Intervertebral Disc Degeneration (spinal disc degeneration): 1 person, 100.00%
  6. Incision Site Abscess: 1 person, 100.00%
  7. Hypoaesthesia (reduced sense of touch or sensation): 1 person, 100.00%
  8. Hyperparathyroidism (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium): 1 person, 100.00%
  9. Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs): 1 person, 100.00%
  10. Device Failure: 1 person, 100.00%

Common conditions people have *:

  1. Arthritis (form of joint disorder that involves inflammation of one or more joints): 1 person, 100.00%

* Approximation only. Some reports may have incomplete information.

Do you take Actonel and have Pain disorder?

Check whether Pain disorder is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Related studies

How severe was Pain disorder and when was it recovered:

Expand to all the drugs that have ingredients of risedronate sodium:

Alternative drugs to, pros and cons of Actonel:

Common Actonel side effects:

Browse all side effects of Actonel:

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Pain disorder treatments and more:

COVID vaccines that are related to Pain disorder:

All the drugs that are associated with Pain disorder:

All the conditions that are associated with Pain disorder:

How the study uses the data?

The study uses data from the FDA. It is based on risedronate sodium (the active ingredients of Actonel) and Actonel (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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