Actonel and Zits - a phase IV clinical study of FDA data


Zits is found among people who take Actonel, especially for people who are female, 50-59 old, have been taking the drug for 1 - 2 years.

The phase IV clinical study analyzes which people take Actonel and have Zits. It is created by eHealthMe based on reports of 28,020 people who have side effects when taking Actonel from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Jun, 01, 2023

28,020 people reported to have side effects when taking Actonel.
Among them, 49 people (0.17%) have Zits.

What is Actonel?

Actonel has active ingredients of risedronate sodium. It is often used in osteoporosis. eHealthMe is studying from 28,458 Actonel users for its effectiveness, alternative drugs and more.

What is Zits?

Zits (pimple/small skin inflammations or lesions/acne) is found to be associated with 2,795 drugs and 2,232 conditions by eHealthMe.

Number of Actonel and Zits reports submitted per year:

Could Actonel cause Zits?

Time on Actonel when people have Zits *:

  • < 1 month: 11.11 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 88.89 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Zits when taking Actonel *:

  • female: 88.89 %
  • male: 11.11 %

Age of people who have Zits when taking Actonel *:

  • 0-1: 0.0 %
  • 2-9: 2.38 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 26.19 %
  • 40-49: 2.38 %
  • 50-59: 35.71 %
  • 60+: 33.33 %

Common drugs people take besides Actonel *:

  1. Herceptin: 13 people, 26.53%
  2. Doxycycline: 12 people, 24.49%
  3. Elidel: 11 people, 22.45%
  4. Neupogen: 11 people, 22.45%
  5. Neulasta: 11 people, 22.45%
  6. Metoclopramide: 11 people, 22.45%
  7. Lovenox: 11 people, 22.45%
  8. Leukine: 11 people, 22.45%
  9. Kytril: 11 people, 22.45%
  10. Kenalog: 11 people, 22.45%

Common side effects people have besides Zits *:

  1. Weight Increased: 24 people, 48.98%
  2. Pain: 19 people, 38.78%
  3. Rashes (redness): 18 people, 36.73%
  4. High Blood Pressure: 16 people, 32.65%
  5. Fatigue (feeling of tiredness): 13 people, 26.53%
  6. Anaemia (lack of blood): 12 people, 24.49%
  7. Conjunctivitis (pink eye): 12 people, 24.49%
  8. Vulvovaginal Dryness: 12 people, 24.49%
  9. Haemorrhoids (a swollen vein or group of veins in the region of the anus): 12 people, 24.49%
  10. Hair Loss: 12 people, 24.49%

Common conditions people have *:

  1. Vitiligo (pigment is lost from areas of the skin): 11 people, 22.45%
  2. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 9 people, 18.37%
  3. Fibromyalgia (a long-term condition which causes pain all over the body): 4 people, 8.16%
  4. Pain: 2 people, 4.08%
  5. Breast Cancer: 2 people, 4.08%
  6. Hyperglycemia (high blood sugar): 2 people, 4.08%
  7. Nausea (feeling of having an urge to vomit): 2 people, 4.08%
  8. Ankylosing Spondylitis (type of arthritis affecting the spine): 2 people, 4.08%
  9. Primary Myelofibrosis (primary disorder of the bone marrow): 1 person, 2.04%
  10. Quit Smoking: 1 person, 2.04%

* Approximation only. Some reports may have incomplete information.

Do you take Actonel and have Zits?

Check whether Zits is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Related studies

How severe was Zits and when was it recovered:

Expand to all the drugs that have ingredients of risedronate sodium:

Alternative drugs to, pros and cons of Actonel:

Common Actonel side effects:

Browse all side effects of Actonel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Zits treatments and more:

  • Zits (164,861 reports)

COVID vaccines that are related to Zits:

Common drugs associated with Zits:

All the drugs that are associated with Zits:

  • Zits (2,795 drugs)

Common conditions associated with Zits:

All the conditions that are associated with Zits:

  • Zits (2,232 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on risedronate sodium (the active ingredients of Actonel) and Actonel (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

Recent studies on eHealthMe: