Acyclovir and Vaginal discharge - a phase IV clinical study of FDA data


Vaginal discharge is found among people who take Acyclovir, especially for people who are 50-59 old, have been taking the drug for < 1 month.

The phase IV clinical study analyzes which people take Acyclovir and have Vaginal discharge. It is created by eHealthMe based on reports of 33,006 people who have side effects when taking Acyclovir from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Oct, 06, 2022

33,006 people reported to have side effects when taking Acyclovir.
Among them, 17 people (0.05%) have Vaginal discharge.

What is Acyclovir?

Acyclovir has active ingredients of acyclovir. It is often used in herpes simplex. eHealthMe is studying from 34,450 Acyclovir users for its effectiveness, alternative drugs and more.

What is Vaginal discharge?

Vaginal discharge is found to be associated with 1,610 drugs and 1,087 conditions by eHealthMe.

Number of Acyclovir and Vaginal discharge reports submitted per year:

Could Acyclovir cause Vaginal discharge?

Time on Acyclovir when people have Vaginal discharge *:

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Age of people who have Vaginal discharge when taking Acyclovir *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 6.67 %
  • 20-29: 13.33 %
  • 30-39: 13.33 %
  • 40-49: 13.33 %
  • 50-59: 40.0 %
  • 60+: 13.33 %

Common drugs people take besides Acyclovir *:

  1. Fluconazole: 7 people, 41.18%
  2. Gyne-Lotrimin: 6 people, 35.29%
  3. Trileptal: 6 people, 35.29%
  4. Neurontin: 6 people, 35.29%
  5. Nystatin: 6 people, 35.29%
  6. Pepcid: 6 people, 35.29%
  7. Ceftriaxone: 6 people, 35.29%
  8. Dilantin: 6 people, 35.29%
  9. Prednisone: 3 people, 17.65%
  10. Hydroxyzine: 3 people, 17.65%

Common side effects people have besides Vaginal discharge *:

  1. Fever: 9 people, 52.94%
  2. Nausea (feeling of having an urge to vomit): 9 people, 52.94%
  3. Skin Exfoliation (removal of the oldest dead skin cells): 8 people, 47.06%
  4. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure): 7 people, 41.18%
  5. Proctalgia (pain in the rectum): 7 people, 41.18%
  6. Erythema Multiforme (a type of hypersensitivity reaction): 7 people, 41.18%
  7. Sinusitis (inflammation of sinus): 7 people, 41.18%
  8. Haematocrit Decreased: 7 people, 41.18%
  9. Headache (pain in head): 7 people, 41.18%
  10. Swallowing Difficulty: 7 people, 41.18%

Common conditions people have *:

  1. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 6 people, 35.29%
  2. Vulvovaginal Dryness: 1 person, 5.88%
  3. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 1 person, 5.88%
  4. Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 1 person, 5.88%
  5. Polymyalgia Rheumatica (pain in many muscles): 1 person, 5.88%
  6. Oral Herpes (viral infection of mouth): 1 person, 5.88%
  7. Mood Swings (an extreme or rapid change in mood): 1 person, 5.88%
  8. Hypersensitivity: 1 person, 5.88%
  9. High Blood Pressure: 1 person, 5.88%
  10. Herpes Virus Infection: 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Acyclovir and have Vaginal discharge?

Check whether Vaginal discharge is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

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Common Acyclovir side effects:

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Vaginal discharge treatments and more:

COVID vaccines that are related to Vaginal discharge:

Common drugs associated with Vaginal discharge:

All the drugs that are associated with Vaginal discharge:

Common conditions associated with Vaginal discharge:

All the conditions that are associated with Vaginal discharge:

How the study uses the data?

The study uses data from the FDA. It is based on acyclovir (the active ingredients of Acyclovir) and Acyclovir (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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