Aggrenox and Thrombocytopenia - a phase IV clinical study of FDA data


We study 7,318 people who have side effects when taking Aggrenox. Thrombocytopenia is found, especially among people who are male, 60+ old, have been taking the drug for 1 - 6 months, also take Exelon and have High blood pressure.

The phase IV clinical study analyzes which people take Aggrenox and have Thrombocytopenia. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Sep, 25, 2023

7,318 people reported to have side effects when taking Aggrenox.
Among them, 97 people (1.33%) have Thrombocytopenia.

What is Aggrenox?

Aggrenox has active ingredients of aspirin; dipyridamole. It is used in stroke. Currently, eHealthMe is studying from 7,541 Aggrenox users.

What is Thrombocytopenia?

Thrombocytopenia (decrease of platelets in blood) is found to be associated with 4,188 drugs and 4,724 conditions by eHealthMe. Currently, we are studying 269,164 people who have Thrombocytopenia.

Number of Aggrenox and Thrombocytopenia reports submitted per year:

Could Aggrenox cause Thrombocytopenia?

Time on Aggrenox when people have Thrombocytopenia *:

  • < 1 month: 16.67 %
  • 1 - 6 months: 54.17 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 29.17 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Thrombocytopenia when taking Aggrenox *:

  • female: 38.37 %
  • male: 61.63 %

Age of people who have Thrombocytopenia when taking Aggrenox *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 7.14 %
  • 50-59: 11.43 %
  • 60+: 81.43 %

Common drugs people take besides Aggrenox *:

  1. Exelon: 13 people, 13.40%
  2. Simvastatin: 10 people, 10.31%
  3. Lipitor: 10 people, 10.31%
  4. Norvasc: 10 people, 10.31%
  5. Lasix: 8 people, 8.25%
  6. Allopurinol: 8 people, 8.25%
  7. Atropine: 8 people, 8.25%
  8. Dexamethasone: 8 people, 8.25%
  9. Neurontin: 8 people, 8.25%
  10. Plavix: 8 people, 8.25%

Common side effects people have besides Thrombocytopenia *:

  1. Anaemia (lack of blood): 21 people, 21.65%
  2. Renal Failure Acute (rapid kidney dysfunction): 18 people, 18.56%
  3. Metabolic Acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body): 13 people, 13.40%
  4. Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 13 people, 13.40%
  5. Chest Pain: 11 people, 11.34%
  6. Acute Myocardial Infarction (acute heart attack): 11 people, 11.34%
  7. Pneumonia: 11 people, 11.34%
  8. Weakness: 10 people, 10.31%
  9. Nausea And Vomiting: 10 people, 10.31%
  10. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 10 people, 10.31%

Common conditions people have *:

  1. High Blood Pressure: 23 people, 23.71%
  2. Dementia (madness): 13 people, 13.40%
  3. Type 2 Diabetes: 13 people, 13.40%
  4. Multiple Myeloma (cancer of the plasma cells): 10 people, 10.31%
  5. Depression: 9 people, 9.28%
  6. Nausea (feeling of having an urge to vomit): 7 people, 7.22%
  7. Insomnia (sleeplessness): 6 people, 6.19%
  8. Stable Angina (a constant chest pain): 6 people, 6.19%
  9. Transient Ischaemic Attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow)): 5 people, 5.15%
  10. Muscle Spasms (muscle contraction): 5 people, 5.15%

* Approximation only. Some reports may have incomplete information.

Do you take Aggrenox and have Thrombocytopenia?

Check whether Thrombocytopenia is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Related studies

How severe was Thrombocytopenia and when was it recovered:

Expand to all the drugs that have ingredients of aspirin; dipyridamole:

Alternative drugs to, pros and cons of Aggrenox:

Browse all side effects of Aggrenox:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Thrombocytopenia treatments and more:

Common drugs associated with Thrombocytopenia:

All the drugs that are associated with Thrombocytopenia:

Common conditions associated with Thrombocytopenia:

All the conditions that are associated with Thrombocytopenia:

How the study uses the data?

The study uses data from the FDA. It is based on aspirin; dipyridamole (the active ingredients of Aggrenox) and Aggrenox (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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