Akineton and Pleurothotonus - a phase IV clinical study of FDA data
Pleurothotonus is found among people who take Akineton, especially for people who are female, 60+ old, have been taking the drug for < 1 month.
The phase IV clinical study analyzes which people take Akineton and have Pleurothotonus. It is created by eHealthMe based on reports of 5,814 people who have side effects when taking Akineton from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
5,814 people reported to have side effects when taking Akineton.
Among them, 18 people (0.31%) have Pleurothotonus.
What is Akineton?
Akineton has active ingredients of biperiden hydrochloride. It is often used in parkinson's disease. eHealthMe is studying from 5,637 Akineton users for its effectiveness, alternative drugs and more.
What is Pleurothotonus?
Pleurothotonus (neurological disorder which occurs due to prolonged exposure to antipsychotic drugs) is found to be associated with 148 drugs and 112 conditions by eHealthMe.
Number of Akineton and Pleurothotonus reports submitted per year:
Time on Akineton when people have Pleurothotonus *:
- < 1 month: 50 %
- 1 - 6 months: 50 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
Gender of people who have Pleurothotonus when taking Akineton *:
- female: 72.22 %
- male: 27.78 %
Age of people who have Pleurothotonus when taking Akineton *:
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 5.56 %
- 40-49: 5.56 %
- 50-59: 44.44 %
- 60+: 44.44 %
Common drugs people take besides Akineton *:
- Haldol: 10 people, 55.56%
- Risperdal: 6 people, 33.33%
- Diazepam: 6 people, 33.33%
- Lamotrigine: 4 people, 22.22%
- Zyprexa: 3 people, 16.67%
- Clozapine: 3 people, 16.67%
- Zopiclone: 3 people, 16.67%
- Levothyroxine Sodium: 3 people, 16.67%
- Simvastatin: 3 people, 16.67%
- Valproate Sodium: 2 people, 11.11%
Common side effects people have besides Pleurothotonus *:
- Fall: 5 people, 27.78%
- Dyskinesia (abnormality or impairment of voluntary movement): 3 people, 16.67%
- Akathisia (a movement disorder characterized by a feeling of inner restlessness): 2 people, 11.11%
- Drug Dependence: 2 people, 11.11%
- Withdrawal Syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance): 1 person, 5.56%
- Dizziness Postural: 1 person, 5.56%
- Drowsiness: 1 person, 5.56%
- Drug Level Increased: 1 person, 5.56%
- Dyslalia (inability to articulate comprehensible speech): 1 person, 5.56%
- Dysphoria (generalized dissatisfaction with life): 1 person, 5.56%
Common conditions people have *:
- Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 3 people, 16.67%
- Stress And Anxiety: 2 people, 11.11%
- Helicobacter Gastritis (inflammation of the inner lining of the stomach caused by helicobacter pylori (h. pylori) a bacterium): 2 people, 11.11%
- Urinary Tract Infection: 1 person, 5.56%
- Schizophrenia, Paranoid Type (delusions and auditory hallucinations but relatively normal intellectual functioning and expression of affect): 1 person, 5.56%
- Schizoaffective Disorder (a mental disorder characterized by disordered thought): 1 person, 5.56%
- Psychomotor Hyperactivity (feelings of extreme restlessness): 1 person, 5.56%
- Osteoarthritis (a joint disease caused by cartilage loss in a joint): 1 person, 5.56%
- Myoclonus (a brief, involuntary twitching of a muscle or a group of muscles): 1 person, 5.56%
- Musculoskeletal Stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 1 person, 5.56%
* Approximation only. Some reports may have incomplete information.
Do you take Akineton and have Pleurothotonus?Check whether Pleurothotonus is associated with a drug or a condition
How to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
How severe was Pleurothotonus and when was it recovered:
Expand to all the drugs that have ingredients of biperiden hydrochloride:
Alternative drugs to, pros and cons of Akineton:
- Akineton (5,637 reports)
Common Akineton side effects:
Browse all side effects of Akineton:a b c d e f g h i j k l m n o p q r s t u v w x y z
Pleurothotonus treatments and more:
- Pleurothotonus (860 reports)
COVID vaccines that are related to Pleurothotonus:
- Pleurothotonus in Moderna COVID Vaccine
- Pleurothotonus in Pfizer BioNTech Covid Vaccine
- Pleurothotonus in Johnson and Johnson Covid Vaccine
Common drugs associated with Pleurothotonus:
All the drugs that are associated with Pleurothotonus:
- Pleurothotonus (148 drugs)
All the conditions that are associated with Pleurothotonus:
- Pleurothotonus (112 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on biperiden hydrochloride (the active ingredients of Akineton) and Akineton (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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