Aldactone and Quincke's disease - a phase IV clinical study of FDA data
Quincke's disease is found among people who take Aldactone, especially for people who are female, 30-39 old.
The phase IV clinical study analyzes which people take Aldactone and have Quincke's disease. It is created by eHealthMe based on reports of 42,831 people who have side effects when taking Aldactone from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
42,831 people reported to have side effects when taking Aldactone.
Among them, 9 people (0.02%) have Quincke's disease.
What is Aldactone?
Aldactone has active ingredients of spironolactone. It is often used in acne. eHealthMe is studying from 43,456 Aldactone users for its effectiveness, alternative drugs and more.
What is Quincke's disease?
Quincke's disease (a form of localized swelling of the deeper layers of the skin and fatty tissues beneath the skin) is found to be associated with 949 drugs and 468 conditions by eHealthMe.
Number of Aldactone and Quincke's disease reports submitted per year:
Gender of people who have Quincke's disease when taking Aldactone *:
- female: 88.89 %
- male: 11.11 %
Age of people who have Quincke's disease when taking Aldactone *:
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 62.5 %
- 40-49: 12.5 %
- 50-59: 12.5 %
- 60+: 12.5 %
Common drugs people take besides Aldactone *:
- Firazyr: 7 people, 77.78%
- Bentyl: 6 people, 66.67%
- Norco: 6 people, 66.67%
- Effexor: 4 people, 44.44%
- Cellcept: 4 people, 44.44%
- Plaquenil: 4 people, 44.44%
- Sinequan: 4 people, 44.44%
- Soma: 4 people, 44.44%
- Protonix: 4 people, 44.44%
- Valtrex: 4 people, 44.44%
Common side effects people have besides Quincke's disease *:
- Sepsis (a severe blood infection that can lead to organ failure and death): 4 people, 44.44%
- Device Related Infection: 4 people, 44.44%
- Renal Impairment (severely reduced kidney function): 3 people, 33.33%
- Renal Embolism (an obstruction in a kidney): 2 people, 22.22%
- Lupus Nephritis (a chronic inflammatory autoimmune disorder that may affect kidney tissue): 2 people, 22.22%
- Transaminases Increased: 1 person, 11.11%
- Therapeutic Response Unexpected: 1 person, 11.11%
- Staphylococcal Infection (an infection with staphylococcus bacteria): 1 person, 11.11%
- Skin Blushing/flushing (a sudden reddening of the face, neck): 1 person, 11.11%
- Pulmonary Oedema (fluid accumulation in the lungs): 1 person, 11.11%
Common conditions people have *:
- Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 4 people, 44.44%
- Pain: 4 people, 44.44%
- Essential Hypertension (primary hypertension): 4 people, 44.44%
- Depression: 4 people, 44.44%
- Breathing Difficulty: 4 people, 44.44%
- Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 1 person, 11.11%
- Psoriasis (immune-mediated disease that affects the skin): 1 person, 11.11%
- Immune System Disorder: 1 person, 11.11%
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 11.11%
- Diabetes: 1 person, 11.11%
* Approximation only. Some reports may have incomplete information.
Do you take Aldactone and have Quincke's disease?Check whether Quincke's disease is associated with a drug or a condition
How to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
How severe was Quincke's disease and when was it recovered:
Expand to all the drugs that have ingredients of spironolactone:
Alternative drugs to, pros and cons of Aldactone:
- Aldactone (43,456 reports)
Common Aldactone side effects:
- Breathing difficulty: 3,116 reports
- Hyperkalemia (damage to or disease of the kidney): 2,693 reports
- Hypotension (abnormally low blood pressure): 2,582 reports
- Diarrhea: 2,411 reports
- Fatigue (feeling of tiredness): 2,247 reports
- Weakness: 2,219 reports
Browse all side effects of Aldactone:a b c d e f g h i j k l m n o p q r s t u v w x y z
Quincke's disease treatments and more:
- Quincke's disease (16,202 reports)
COVID vaccines that are related to Quincke's disease:
- Quincke's disease in Moderna COVID Vaccine
- Quincke's disease in Pfizer BioNTech Covid Vaccine
- Quincke's disease in Johnson and Johnson Covid Vaccine
Common drugs associated with Quincke's disease:
- Firazyr: 1,985 reports
- Kalbitor: 787 reports
- Heparin: 440 reports
- Hydramine: 413 reports
- Epipen: 379 reports
- Diphen: 348 reports
- Zyrtec: 273 reports
- Benadryl: 260 reports
- Zofran: 244 reports
- Vitamin d: 217 reports
All the drugs that are associated with Quincke's disease:
- Quincke's disease (949 drugs)
Common conditions associated with Quincke's disease:
All the conditions that are associated with Quincke's disease:
- Quincke's disease (468 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on spironolactone (the active ingredients of Aldactone) and Aldactone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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