Aldactone and Vestibular disorder - a phase IV clinical study of FDA data

• Aldactone (43,452 reports)

• Abasia (inability to walk): 116 reports
• Abdominal discomfort: 343 reports
• Abdominal distension: 602 reports
• Abdominal pain: 1,049 reports
• Abdominal pain upper: 612 reports
• Abscess (pus): 104 reports
• Acute kidney failure: 1,597 reports
• Acute myocardial infarction (acute heart attack): 261 reports
• Acute pulmonary oedema (sudden deposit of fluid in the lung)): 109 reports
• Acute respiratory failure: 192 reports
• Agitation (state of anxiety or nervous excitement): 277 reports
• Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 633 reports
• Alanine aminotransferase increased: 648 reports
• Altered state of consciousness (altered state of mind): 246 reports
• Ammonia increased: 161 reports
• Anaemia (lack of blood): 2,155 reports
• Angina unstable (chest pain due to ischemia of the heart muscle- unstable): 108 reports
• Anhedonia (inability to experience pleasure from activities usually found enjoyable): 229 reports
• Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight): 244 reports
• Anuria (failure of the kidneys to produce urine): 149 reports
• Aortic stenosis (obstruction to the outflow of blood from the left ventricle into the aorta): 105 reports
• Aortic valve incompetence: 111 reports
• Appetite - decreased (decreased appetite occurs when you have a reduced desire to eat): 1,152 reports
• Ards (acute respiratory distress syndrome) (sudden failure of the respiratory (breathing) system): 156 reports
• Arrhythmias (irregular heartbeat): 753 reports
• Arthritis (form of joint disorder that involves inflammation of one or more joints): 229 reports
• Arthropathy: 140 reports
• Ascites (accumulation of fluid in the abdominal cavity): 1,170 reports
• Aseptic necrosis (the death of bone tissue due to a lack of blood supply): 138 reports
• Aspartate aminotransferase increased: 727 reports
• Asthma: 255 reports
• Atelectasis (partial or complete collapse of the lung): 244 reports
• Atherosclerosis (disorder of the arteries): 137 reports
• Atrial fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1,226 reports
• Atrioventricular block (heart block): 147 reports
• Atrioventricular block complete (heart block complete): 183 reports
• Atrioventricular block first degree (heart block first degree): 120 reports
• Back pain: 838 reports
• Balance disorder: 244 reports
• Bleeding disorders: 199 reports
• Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure): 222 reports
• Blood albumin decreased: 152 reports
• Blood alkaline phosphatase increased: 376 reports
• Blood bilirubin increased: 551 reports
• Blood creatine phosphokinase increased: 237 reports
• Blood creatinine increased: 1,111 reports
• Blood glucose decreased: 121 reports
• Blood glucose increased: 605 reports
• Blood lactate dehydrogenase increased: 246 reports
• Blood potassium decreased: 295 reports
• Blood pressure fluctuation: 118 reports
• Blood sodium decreased: 291 reports
• Blood urea increased: 681 reports
• Blood uric acid increased: 128 reports
• Bone disorder: 165 reports
• Bone pain: 181 reports
• Bradycardia (abnormally slow heart action): 950 reports
• Brain natriuretic peptide increased: 126 reports
• Breathing difficulty: 3,076 reports
• Breathing - slowed or stopped: 131 reports
• Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 497 reports
• Bundle branch block left (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the left ventricle): 121 reports
• Burning sensation: 119 reports
• Cardiac arrest: 590 reports
• Cardiac disorder: 454 reports
• Cardiac failure: 2,014 reports
• Cardiac failure acute: 124 reports
• Cardiac failure chronic: 191 reports
• Cardiac failure congestive: 1,550 reports
• Cardiac murmur (an heart sound in valve abnormality): 201 reports
• Cardioactive drug level increased: 130 reports
• Cardiogenic shock (inadequate circulation of blood): 252 reports
• Cardiomyopathy (weakening of the heart muscle): 336 reports
• Cardio-respiratory arrest (sudden dysfunction of heart and lungs): 399 reports
• Cataract (clouding of the lens inside the eye): 221 reports
• Cellulitis (infection under the skin): 438 reports
• Cerebral haemorrhage (bleeding within the brain): 204 reports
• Cerebral infarction (less blood supply to brain resulting tissue damage): 265 reports
• Chest pain: 1,336 reports
• Chills (felling of cold): 327 reports
• Cholecystitis (infection of gallbladder): 117 reports
• Cholestasis (a condition where bile cannot flow from the liver to the duodenum): 175 reports
• Chronic kidney disease: 393 reports
• Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe): 436 reports
• Circulatory collapse: 126 reports
• Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving): 113 reports
• Confusion: 343 reports
• Confusional state: 844 reports
• Congestive cardiomyopathy (weakening of heart muscle): 176 reports
• Consciousness - decreased: 255 reports
• Constipation: 840 reports
• Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 212 reports
• Coronary heart disease (narrowing or blockage of the coronary arteries): 300 reports
• Cough: 970 reports
• Coughing up blood: 280 reports
• C-reactive protein increased: 371 reports
• Cytolytic hepatitis (dissolution or destruction of a liver cell): 103 reports
• Death: 1,478 reports
• Deep venous thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 323 reports
• Dehydration (dryness resulting from the removal of water): 1,574 reports
• Delirium (wild excitement): 194 reports
• Depressed level of consciousness: 361 reports
• Depressed mood: 101 reports
• Depression: 675 reports
• Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it): 172 reports
• Device related infection: 188 reports
• Diabetes: 396 reports
• Diabetes mellitus inadequate control: 147 reports
• Dialysis: 139 reports
• Diarrhea: 2,411 reports
• Discomfort: 110 reports
• Disease progression: 427 reports
• Disseminated intravascular coagulation (systemic activation of blood coagulation): 235 reports
• Disturbance in attention: 127 reports
• Dizziness: 1,683 reports
• Drowsiness: 720 reports
• Drug eruption (adverse drug reaction of the skin): 120 reports
• Drug hypersensitivity: 386 reports
• Drug ineffective: 914 reports
• Drug intolerance (drug sensitivity): 151 reports
• Dry mouth: 168 reports
• Dry skin: 161 reports
• Dyspnea exertional: 458 reports
• Ecchymosis (a discoloration of the skin resulting from bleeding underneath): 118 reports
• Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 160 reports
• Ejection fraction decreased (systolic heart failure): 269 reports
• Electrocardiogram qt prolonged: 233 reports
• Electrolyte imbalance: 125 reports
• Emotional distress: 282 reports
• Encephalopathy (functioning of the brain is affected by some agent or condition): 355 reports
• Enlarged heart: 431 reports
• Eosinophilia (eosinophil count in the peripheral blood exceeds): 130 reports
• Erythema multiforme (a type of hypersensitivity reaction): 453 reports
• Face oedema (swelling of face): 154 reports
• Faeces discolored: 116 reports
• Fainting (loss of consciousness and postural tone): 817 reports
• Fall: 1,825 reports
• Fatigue (feeling of tiredness): 2,247 reports
• Fear: 127 reports
• Febrile neutropenia (fever with reduced white blood cells): 179 reports
• Femur fracture: 107 reports
• Fever: 1,707 reports
• Flatulence (flatus expelled through the anus): 156 reports
• Fluid overload (too much fluid in the blood): 318 reports
• Fluid retention (an abnormal accumulation of fluid in the blood): 607 reports
• Gait disturbance: 551 reports
• Gallbladder disorder: 101 reports
• Gallstones (stone formation by bile component): 313 reports
• Gamma-glutamyltransferase increased: 381 reports
• Gastric ulcer (stomach ulcer): 368 reports
• Gastritis (inflammation of stomach): 196 reports
• Gastroenteritis (inflammation of stomach and intestine): 159 reports
• Gastroesophageal reflux disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 451 reports
• Gastrointestinal disorder (functional problems of gastrointestinal tract): 190 reports
• Gastrointestinal haemorrhage (bleeding gastrointestinal tract): 943 reports
• Generalised oedema (swelling all over the body): 220 reports
• General physical health deterioration (weak health status): 747 reports
• Gout (uric acid crystals building up in the body): 136 reports
• Gynecomastia (enlargement of the gland tissue of the male breast): 160 reports
• Haematemesis (vomiting of blood): 214 reports
• Haematochezia (passage of stools containing blood): 163 reports
• Haematocrit decreased: 344 reports
• Haematoma (collection of blood outside the blood vessels): 300 reports
• Haematuria (presence of blood in urine): 233 reports
• Haemoglobin decreased: 912 reports
• Haemorrhage (bleeding): 397 reports
• Haemorrhagic anaemia (anaemia due to excessive bleeding): 125 reports
• Haemorrhoids (a swollen vein or group of veins in the region of the anus): 110 reports
• Hair loss: 318 reports
• Hallucinations (sensations that appear real but are created by your mind): 141 reports
• Headache (pain in head): 1,264 reports
• Head injury: 490 reports
• Heart attack: 764 reports
• Heart palpitations (feelings or sensations that your heart is pounding or racing): 514 reports
• Heart rate decreased: 182 reports
• Heart rate increased: 351 reports
• Heart rate irregular: 155 reports
• Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue): 577 reports
• Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure): 769 reports
• Hepatic enzyme increased: 170 reports
• Hepatic failure (liver failure): 688 reports
• Hepatic neoplasm malignant (liver cancer): 269 reports
• Hepatic steatosis (fatty liver disease): 117 reports
• Hepatitis (inflammation of the liver): 226 reports
• Hepatocellular carcinoma (liver cancer): 106 reports
• Hepatocellular injury (liver injury): 123 reports
• Hepatomegaly (abnormal enlargement of the liver): 201 reports
• Hepatorenal syndrome (renal failure in patients with advanced chronic liver disease): 107 reports
• Herpes zoster: 162 reports
• Hiatal hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm): 140 reports
• High blood cholesterol: 288 reports
• High blood pressure: 1,280 reports
• Hip fracture: 117 reports
• Hoarseness or changing voice: 237 reports
• Hospitalisation: 169 reports
• Hot flush (sudden feelings of heat): 111 reports
• Hyperbilirubinaemia (excess of bilirubin in the blood): 181 reports
• Hyperglycemia (high blood sugar): 271 reports
• Hyperhidrosis (abnormally increased sweating): 365 reports
• Hyperkalemia (damage to or disease of the kidney): 2,693 reports
• Hyperlipidaemia (presence of excess lipids in the blood): 178 reports
• Hypernatraemia (an abnormally high plasma concentration of sodium ions): 118 reports
• Hypersensitivity: 291 reports
• Hyperthyroidism (over activity of the thyroid gland): 131 reports
• Hyperuricaemia (level of uric acid in the blood that is abnormally high): 136 reports
• Hypoaesthesia (reduced sense of touch or sensation): 465 reports
• Hypoalbuminaemia (levels of albumin in blood serum are abnormally low): 157 reports
• Hypocalcaemia (levels of calcium in blood serum are abnormally low): 115 reports
• Hypoglycemia (low blood sugar): 511 reports
• Hypokalemia (low potassium): 728 reports
• Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 1,409 reports
• Hypophagia (reduced food intake): 194 reports
• Hypotension (abnormally low blood pressure): 2,582 reports
• Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 227 reports
• Hypovolaemia (a decreased volume of circulating blood in the body): 129 reports
• Ill-defined disorder: 110 reports
• Impaired healing: 144 reports
• Indigestion: 287 reports
• Infection: 397 reports
• Inflammation: 194 reports
• Influenza like illness: 135 reports
• Injection site pain: 199 reports
• Injury: 454 reports
• Insomnia (sleeplessness): 630 reports
• International normalised ratio increased: 645 reports
• Interstitial lung disease: 529 reports
• Intervertebral disc protrusion (spinal disc protrusion): 109 reports
• Intestinal obstruction: 173 reports
• Iron deficiency anaemia: 188 reports
• Ischaemic cardiomyopathy (weakness in the muscle of the heart due to inadequate oxygen delivery to the myocardium with coronary artery disease): 109 reports
• Itching: 807 reports
• Jaundice - yellow skin (a yellowish pigmentation of the skin): 298 reports
• Joint pain: 841 reports
• Joint swelling: 247 reports
• Kidney stones: 117 reports
• Lactic acidosis (low ph in body tissues): 247 reports
• Left ventricular dysfunction: 136 reports
• Left ventricular hypertrophy (the thickening of the myocardium (muscle) of the left ventricle of the heart): 136 reports
• Leukocytosis (increased white blood cells): 145 reports
• Leukopenia (less number of white blood cells in blood): 255 reports
• Limb injury: 141 reports
• Liver disorder (liver diseases): 434 reports
• Loss of consciousness: 623 reports
• Lower gastrointestinal haemorrhage (bleeding in the large intestine, rectum, or anus is called lower gi bleeding): 113 reports
• Low tissue oxygen: 281 reports
• Lung disorder (lung disease): 278 reports
• Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung): 130 reports
• Lymph follicular hypertrophy (an increase in the size of the lymph node follicles): 145 reports
• Lymphocyte count decreased: 102 reports
• Malaise (a feeling of general discomfort or uneasiness): 1,699 reports
• Malignant neoplasm progression (cancer tumour came back): 297 reports
• Malnutrition (condition that results from eating a diet in which certain nutrients are lacking): 116 reports
• Melaena (the passage of black, tarry stools): 357 reports
• Memory loss: 442 reports
• Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation): 207 reports
• Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body): 304 reports
• Metastases to bone (cancer spreads to bone): 112 reports
• Metastases to liver (cancer spreads to liver): 120 reports
• Migraine (headache): 171 reports
• Mitral valve incompetence (inefficient heart valve): 360 reports
• Mobility decreased (ability to move is reduced): 164 reports
• Mucosal inflammation (infection of mucous membrane): 107 reports
• Multi-organ failure (multisystem organ failure): 377 reports
• Multiple injuries: 149 reports
• Muscle aches (muscle pain): 440 reports
• Muscle spasms (muscle contraction): 482 reports
• Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 215 reports
• Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 122 reports
• Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased): 137 reports
• Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 209 reports
• Nasopharyngitis (inflammation of the nasopharynx): 324 reports
• Nausea (feeling of having an urge to vomit): 2,354 reports
• Nausea and vomiting: 1,637 reports
• Neck pain: 191 reports
• Neoplasm malignant (cancer tumour): 121 reports
• Nephrogenic anaemia (anaemia due to kidney disease): 109 reports
• Nervousness: 114 reports
• Neuropathy peripheral (surface nerve damage): 283 reports
• Neutrophil count decreased (less than normal number of neutrophil a type of blood cell): 187 reports
• Nosebleed (bleeding from nose): 529 reports
• Oedema (fluid collection in tissue): 916 reports
• Oedema lower limb (fluid collection in tissue of lower leg): 132 reports
• Oedema peripheral (superficial swelling): 1,696 reports
• Oesophageal varices haemorrhage (bleeding from extremely dilated sub-mucosal veins in the lower third of the oesophagus): 129 reports
• Oral candidiasis (fungal infection of mouth): 105 reports
• Oropharyngeal pain: 191 reports
• Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up): 217 reports
• Osteoarthritis (a joint disease caused by cartilage loss in a joint): 242 reports
• Osteomyelitis (infection of bone): 165 reports
• Osteonecrosis of jaw (death of bone of jaw): 200 reports
• Osteopenia (a condition where bone mineral density is lower than normal): 105 reports
• Osteoporosis (bones weak and more likely to break): 146 reports
• Overdose: 356 reports
• Oxygen saturation decreased: 356 reports
• Pain: 1,454 reports
• Pain in extremity: 895 reports
• Pain in jaw: 294 reports
• Paleness (unusual lightness of skin colour): 110 reports
• Palmar-plantar erythrodysaesthesia syndrome (hand-foot syndrome): 235 reports
• Pancreatitis (inflammation of pancreas): 216 reports
• Pancreatitis acute (sudden inflammation of pancreas): 148 reports
• Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 421 reports
• Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 265 reports
• Paroxysmal supraventricular tachycardia: 103 reports
• Pericardial effusion (fluid around the heart): 314 reports
• Peripheral swelling: 394 reports
• Pleural effusion (water on the lungs): 1,003 reports
• Pneumonia: 1,803 reports
• Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree): 191 reports
• Pollakiuria (abnormally frequent passage of relatively small quantities or urine): 114 reports
• Portal hypertension (increase in the blood pressure within a system of veins called the portal venous system): 107 reports
• Presyncope: 165 reports
• Primary pulmonary hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 373 reports
• Productive cough: 205 reports
• Protein - urine: 120 reports
• Pulmonary congestion (congestion in the lungs): 227 reports
• Pulmonary embolism (blockage of the main artery of the lung): 403 reports
• Pulmonary hypertension (increase in blood pressure in the lung artery): 621 reports
• Pulmonary oedema (fluid accumulation in the lungs): 581 reports
• Purpura (purplish discoloration of the skin): 149 reports
• Rales (an abnormal respiratory sound characterized by fine crackles): 123 reports
• Rash erythematous (redness of the skin): 175 reports
• Rashes (redness): 1,327 reports
• Rash maculo-papular (red area on the skin that is covered with small confluent bumps): 126 reports
• Rectal haemorrhage (bleeding from anus): 249 reports
• Red blood cell count decreased: 197 reports
• Renal disorder (kidney disease): 302 reports
• Renal failure acute (rapid kidney dysfunction): 1,692 reports
• Renal failure chronic (long lasting kidney dysfunction): 211 reports
• Renal impairment (severely reduced kidney function): 1,088 reports
• Renal injury (kidney injury): 159 reports
• Respiratory acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 680 reports
• Respiratory disorder (respiratory disease): 122 reports
• Respiratory distress (difficulty in breathing): 292 reports
• Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down): 375 reports
• Rib fracture: 122 reports
• Right ventricular failure (right half of the heart fails to work): 476 reports
• Seizures (abnormal excessive or synchronous neuronal activity in the brain): 110 reports
• Sepsis (a severe blood infection that can lead to organ failure and death): 780 reports
• Septic shock (shock due to blood infection): 388 reports
• Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin): 242 reports
• Shock haemorrhagic (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin due to excess bleeding): 143 reports
• Sinus bradycardia (an unusually slow heartbeat due to heart disease): 165 reports
• Sinusitis (inflammation of sinus): 310 reports
• Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node): 101 reports
• Skin blushing/flushing (a sudden reddening of the face, neck): 267 reports
• Skin discoloration: 111 reports
• Skin discoloration - bluish (bluish colour of skin): 114 reports
• Skin exfoliation (removal of the oldest dead skin cells): 131 reports
• Skin ulcer: 248 reports
• Sleep apnea syndrome: 161 reports
• Sleep disorder: 105 reports
• Speech disorder: 187 reports
• Speech impairment (adult) (inability to speak (adult)): 221 reports
• Splenomegaly (enlargement of spleen): 159 reports
• Stable angina (a constant chest pain): 184 reports
• Staphylococcal infection (an infection with staphylococcus bacteria): 218 reports
• Stomatitis (inflammation of mucous membrane of mouth): 217 reports
• Stress and anxiety: 1,013 reports
• Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 457 reports
• Subdural haematoma (blood collects between the skull and the surface of the brain): 151 reports
• Surgery: 161 reports
• Swallowing difficulty: 355 reports
• Swelling: 332 reports
• Swelling face: 149 reports
• Tachypnea: 104 reports
• Taste - impaired: 144 reports
• The flu (the flu is caused by an influenza virus): 307 reports
• Therapeutic agent toxicity (poisoning by ability to cure substance): 154 reports
• Thirst: 146 reports
• Thrombocytopenia (decrease of platelets in blood): 1,759 reports
• Thrombosis (formation of a blood clot inside a blood vessel): 204 reports
• Tinnitus (a ringing in the ears): 110 reports
• Toxic skin eruption (skin breakdown due to toxic substance): 128 reports
• Transaminases increased: 121 reports
• Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow)): 145 reports
• Tremor (trembling or shaking movements in one or more parts of your body): 372 reports
• Tricuspid valve incompetence (inefficient heart valve): 270 reports
• Type 2 diabetes: 153 reports
• Upper gastrointestinal haemorrhage (upper gastrointestinal bleeding): 238 reports
• Upper respiratory tract infection: 195 reports
• Urinary incontinence (inability to control the flow of urine and involuntary urination): 134 reports
• Urinary retention (the inability to completely or partially empty the bladder): 160 reports
• Urinary tract infection: 917 reports
• Urination - painful: 141 reports
• Urine output decreased: 126 reports
• Urine output - decreased: 127 reports
• Urticaria (rash of round, red welts on the skin that itch intensely): 192 reports
• Varices oesophageal (enlarged and swollen veins at the bottom of the oesophagus, near the stomach): 132 reports
• Ventricular extrasystoles (premature cardiac contraction): 165 reports
• Ventricular fibrillation (abnormally irregular heart rhythm): 220 reports
• Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart): 408 reports
• Viral infection: 124 reports
• Vision blurred: 306 reports
• Visual acuity reduced (reduced clearness of vision): 124 reports
• Visual impairment: 176 reports
• Weakness: 2,215 reports
• Weight decreased: 1,088 reports
• Weight increased: 936 reports
• Weight loss: 141 reports
• Wheezing (a high-pitched whistling sound made while you breath): 189 reports
• White blood cell count decreased: 512 reports
• White blood cell count increased: 309 reports

• Vestibular disorder (1,531 reports)

All the drugs that are associated with Vestibular disorder:

• Vestibular disorder (652 drugs)

All the conditions that are associated with Vestibular disorder:

• Vestibular disorder (361 conditions)

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