Alendronate sodium and Palatal disorder - a phase IV clinical study of FDA data

Summary:

We study 40,203 people who have side effects when taking Alendronate sodium. Palatal disorder is found, especially among people who are female, 60+ old, have been taking the drug for 6 - 12 months, also take Fosamax and have High blood pressure.

The phase IV clinical study analyzes which people take Alendronate sodium and have Palatal disorder. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Sep, 30, 2023

40,203 people reported to have side effects when taking Alendronate sodium.
Among them, 14 people (0.03%) have Palatal disorder.

What is Alendronate sodium?

Alendronate sodium has active ingredients of alendronate sodium. It is used in osteoporosis. Currently, eHealthMe is studying from 40,879 Alendronate sodium users.

What is Palatal disorder?

Palatal disorder is found to be associated with 366 drugs and 191 conditions by eHealthMe. Currently, we are studying 786 people who have Palatal disorder.

Number of Alendronate sodium and Palatal disorder reports submitted per year:

Could Alendronate sodium cause Palatal disorder?

Time on Alendronate sodium when people have Palatal disorder *:

Gender of people who have Palatal disorder when taking Alendronate sodium *:

female: 100 %
male: 0.0 %

Age of people who have Palatal disorder when taking Alendronate sodium *:

Common drugs people take besides Alendronate sodium *:

Common side effects people have besides Palatal disorder *:

Osteonecrosis Of Jaw (death of bone of jaw): 11 people, 78.57%
Fall: 7 people, 50.00%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 7 people, 50.00%
Ankle Fracture: 7 people, 50.00%
Carpal Tunnel Syndrome (nerve compression at wrist results numbness weakness, pain , swelling): 7 people, 50.00%
Tooth Disorder (tooth disease): 7 people, 50.00%
Dental Caries: 7 people, 50.00%
Tooth Abscess (pus formation in tooth): 6 people, 42.86%
Femur Fracture: 6 people, 42.86%
Depression: 6 people, 42.86%

Common conditions people have *:

Osteoarthritis (a joint disease caused by cartilage loss in a joint): 3 people, 21.43%
Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 21.43%
High Blood Pressure: 3 people, 21.43%
Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose): 1 person, 7.14%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 7.14%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 7.14%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Alendronate sodium and have Palatal disorder?

Check whether Palatal disorder is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Stuckey BG, Sallie R, "Alendronate-induced unmasking or deterioration of coeliac disease: a case series", Osteoporosis International, 2015 Jan .
Lee WY, Sun LM, Lin MC, Liang JA, Chang SN, Sung FC, Muo CH, Kao CH, "A higher dosage of oral alendronate will increase the subsequent cancer risk of osteoporosis patients in Taiwan: a population-based cohort study", PloS one, 2012 Dec .

Related studies

All the conditions that are associated with Palatal disorder:

Palatal disorder (191 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on alendronate sodium (the active ingredients of Alendronate sodium) and Alendronate sodium (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.