Allegra and Akathisia - a phase IV clinical study of FDA data


Akathisia is found among people who take Allegra, especially for people who are female, 10-19 old.

The phase IV clinical study analyzes which people take Allegra and have Akathisia. It is created by eHealthMe based on reports of 66,294 people who have side effects when taking Allegra from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Jun, 05, 2023

66,294 people reported to have side effects when taking Allegra.
Among them, 31 people (0.05%) have Akathisia.

What is Allegra?

Allegra has active ingredients of fexofenadine hydrochloride. It is often used in allergies. eHealthMe is studying from 68,571 Allegra users for its effectiveness, alternative drugs and more.

What is Akathisia?

Akathisia (a movement disorder characterized by a feeling of inner restlessness) is found to be associated with 1,318 drugs and 791 conditions by eHealthMe.

Number of Allegra and Akathisia reports submitted per year:

Could Allegra cause Akathisia?

Gender of people who have Akathisia when taking Allegra *:

  • female: 56.67 %
  • male: 43.33 %

Age of people who have Akathisia when taking Allegra *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 50.0 %
  • 20-29: 0.0 %
  • 30-39: 12.5 %
  • 40-49: 18.75 %
  • 50-59: 18.75 %
  • 60+: 0.0 %

Common drugs people take besides Allegra *:

  1. Paxil: 15 people, 48.39%
  2. Concerta: 8 people, 25.81%
  3. Celebrex: 7 people, 22.58%
  4. Albuterol: 7 people, 22.58%
  5. Mirapex: 6 people, 19.35%
  6. Lipitor: 6 people, 19.35%
  7. Vioxx: 6 people, 19.35%
  8. Metoclopramide: 5 people, 16.13%
  9. Celexa: 5 people, 16.13%
  10. Vicodin: 5 people, 16.13%

Common side effects people have besides Akathisia *:

  1. Stress And Anxiety: 20 people, 64.52%
  2. Tremor (trembling or shaking movements in one or more parts of your body): 14 people, 45.16%
  3. Insomnia (sleeplessness): 12 people, 38.71%
  4. Agitation (state of anxiety or nervous excitement): 12 people, 38.71%
  5. Suicidal Ideation: 12 people, 38.71%
  6. Weight Decreased: 11 people, 35.48%
  7. Suicide Attempt: 11 people, 35.48%
  8. Dizziness: 11 people, 35.48%
  9. Chest Pain: 9 people, 29.03%
  10. Apathy: 9 people, 29.03%

Common conditions people have *:

  1. Stress And Anxiety: 9 people, 29.03%
  2. Depression: 9 people, 29.03%
  3. Asthma: 5 people, 16.13%
  4. High Blood Pressure: 5 people, 16.13%
  5. Sleep Disorder: 3 people, 9.68%
  6. Schizoaffective Disorder (a mental disorder characterized by disordered thought): 3 people, 9.68%
  7. Parkinson's Disease: 3 people, 9.68%
  8. Diabetes: 3 people, 9.68%
  9. Musculoskeletal Pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 3 people, 9.68%
  10. Initial Insomnia (feeling of inadequate or poor-quality sleep): 3 people, 9.68%

* Approximation only. Some reports may have incomplete information.

Do you take Allegra and have Akathisia?

Check whether Akathisia is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Related studies

How severe was Akathisia and when was it recovered:

Expand to all the drugs that have ingredients of fexofenadine hydrochloride:

Alternative drugs to, pros and cons of Allegra:

Common Allegra side effects:

Browse all side effects of Allegra:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Akathisia treatments and more:

COVID vaccines that are related to Akathisia:

Common drugs associated with Akathisia:

All the drugs that are associated with Akathisia:

Common conditions associated with Akathisia:

All the conditions that are associated with Akathisia:

How the study uses the data?

The study uses data from the FDA. It is based on fexofenadine hydrochloride (the active ingredients of Allegra) and Allegra (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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