Allopurinol and Anaemia haemolytic autoimmune - a phase IV clinical study of FDA data


We study 178,791 people who have side effects when taking Allopurinol. Anaemia haemolytic autoimmune is found, especially among people who are male, 60+ old, have been taking the drug for 6 - 12 months, also take Cyclophosphamide and have Chronic lymphocytic leukaemia.

The phase IV clinical study analyzes which people take Allopurinol and have Anaemia haemolytic autoimmune. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Sep, 25, 2023

178,791 people reported to have side effects when taking Allopurinol.
Among them, 44 people (0.02%) have Anaemia haemolytic autoimmune.

What is Allopurinol?

Allopurinol has active ingredients of allopurinol. It is used in gout. Currently, eHealthMe is studying from 181,418 Allopurinol users.

What is Anaemia haemolytic autoimmune?

Anaemia haemolytic autoimmune (condition in which the immune system attacks the red blood cells, resulting in fewer of these oxygen-transporting cells) is found to be associated with 621 drugs and 423 conditions by eHealthMe. Currently, we are studying 1,609 people who have Anaemia haemolytic autoimmune.

Number of Allopurinol and Anaemia haemolytic autoimmune reports submitted per year:

Could Allopurinol cause Anaemia haemolytic autoimmune?

Time on Allopurinol when people have Anaemia haemolytic autoimmune *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 100 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Anaemia haemolytic autoimmune when taking Allopurinol *:

  • female: 35.14 %
  • male: 64.86 %

Age of people who have Anaemia haemolytic autoimmune when taking Allopurinol *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 10.26 %
  • 40-49: 5.13 %
  • 50-59: 7.69 %
  • 60+: 76.92 %

Common drugs people take besides Allopurinol *:

  1. Omeprazole: 8 people, 18.18%
  2. Cyclophosphamide: 8 people, 18.18%
  3. Lasix: 7 people, 15.91%
  4. Folic Acid: 7 people, 15.91%
  5. Aspirin: 6 people, 13.64%
  6. Lantus: 5 people, 11.36%
  7. Furosemide: 5 people, 11.36%
  8. Atenolol: 5 people, 11.36%
  9. Ramipril: 5 people, 11.36%
  10. Revlimid: 5 people, 11.36%

Common side effects people have besides Anaemia haemolytic autoimmune *:

  1. Breathing Difficulty: 11 people, 25.00%
  2. High Blood Pressure: 5 people, 11.36%
  3. Urinary Tract Infection: 5 people, 11.36%
  4. Nausea And Vomiting: 5 people, 11.36%
  5. Thrombocytopenia (decrease of platelets in blood): 5 people, 11.36%
  6. Abdominal Pain: 4 people, 9.09%
  7. Consciousness - Decreased: 4 people, 9.09%
  8. Hypotension (abnormally low blood pressure): 4 people, 9.09%
  9. Full Blood Count Decreased: 4 people, 9.09%
  10. Oxygen Saturation Decreased: 4 people, 9.09%

Common conditions people have *:

  1. Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 8 people, 18.18%
  2. Hyperuricaemia (level of uric acid in the blood that is abnormally high): 5 people, 11.36%
  3. Constipation: 4 people, 9.09%
  4. Pneumonia: 4 people, 9.09%
  5. High Blood Pressure: 3 people, 6.82%
  6. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 6.82%
  7. Cardiac Failure: 2 people, 4.55%
  8. Diabetes: 2 people, 4.55%
  9. Gastrointestinal Stromal Tumor: 2 people, 4.55%
  10. Wheezing (a high-pitched whistling sound made while you breath): 2 people, 4.55%

* Approximation only. Some reports may have incomplete information.

Do you take Allopurinol and have Anaemia haemolytic autoimmune?

Check whether Anaemia haemolytic autoimmune is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Anaemia haemolytic autoimmune and when was it recovered:

Expand to all the drugs that have ingredients of allopurinol:

Alternative drugs to, pros and cons of Allopurinol:

Browse all side effects of Allopurinol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Anaemia haemolytic autoimmune treatments and more:

Common drugs associated with Anaemia haemolytic autoimmune:

All the drugs that are associated with Anaemia haemolytic autoimmune:

All the conditions that are associated with Anaemia haemolytic autoimmune:

How the study uses the data?

The study uses data from the FDA. It is based on allopurinol (the active ingredients of Allopurinol) and Allopurinol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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