Allopurinol and Ear barotrauma - a phase IV clinical study of FDA data

Summary:

Ear barotrauma is found among people who take Allopurinol, especially for people who are male, 60+ old.

The phase IV clinical study analyzes which people take Allopurinol and have Ear barotrauma. It is created by eHealthMe based on reports of 164,051 people who have side effects when taking Allopurinol from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.



On Jan, 29, 2023

164,051 people reported to have side effects when taking Allopurinol.
Among them, 12 people (0.01%) have Ear barotrauma.


What is Allopurinol?

Allopurinol has active ingredients of allopurinol. It is often used in gout. eHealthMe is studying from 166,561 Allopurinol users for its effectiveness, alternative drugs and more.

What is Ear barotrauma?

Ear barotrauma (discomfort and possible damage in the ear due to pressure differences between the inside and outside of the eardrum) is found to be associated with 929 drugs and 564 conditions by eHealthMe.

Number of Allopurinol and Ear barotrauma reports submitted per year:

Could Allopurinol cause Ear barotrauma?

Gender of people who have Ear barotrauma when taking Allopurinol *:

  • female: 8.33 %
  • male: 91.67 %

Age of people who have Ear barotrauma when taking Allopurinol *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 100 %

Common drugs people take besides Allopurinol *:

  1. Zometa: 11 people, 91.67%
  2. Levaquin: 11 people, 91.67%
  3. Lortab: 10 people, 83.33%
  4. Atenolol: 7 people, 58.33%
  5. Furosemide: 7 people, 58.33%
  6. Coreg: 7 people, 58.33%
  7. Lansoprazole: 7 people, 58.33%
  8. Compazine: 7 people, 58.33%
  9. Mitoxantrone: 7 people, 58.33%
  10. Celebrex: 7 people, 58.33%

Common side effects people have besides Ear barotrauma *:

  1. Dizziness: 12 people, 100.00%
  2. Spinal Osteoarthritis (joint cartilage loss in spine): 11 people, 91.67%
  3. Stress And Anxiety: 11 people, 91.67%
  4. Pneumonia: 11 people, 91.67%
  5. Prostatomegaly (enlargement of the prostate): 11 people, 91.67%
  6. Pain: 11 people, 91.67%
  7. Deafness Neurosensory: 11 people, 91.67%
  8. Breathing Difficulty: 11 people, 91.67%
  9. Back Pain: 11 people, 91.67%
  10. Osteonecrosis Of Jaw (death of bone of jaw): 11 people, 91.67%

Common conditions people have *:

  1. High Blood Pressure: 8 people, 66.67%
  2. Abdominal Discomfort: 7 people, 58.33%
  3. Hypercalcaemia Of Malignancy (elevated calcium (ca+) level in the blood with cancer): 4 people, 33.33%
  4. Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 1 person, 8.33%
  5. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 1 person, 8.33%
  6. Pancreatitis Chronic (chronic inflammation of pancreas): 1 person, 8.33%
  7. Pain: 1 person, 8.33%
  8. Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 1 person, 8.33%
  9. Multiple Myeloma (cancer of the plasma cells): 1 person, 8.33%
  10. Metastases To Bone (cancer spreads to bone): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Allopurinol and have Ear barotrauma?

Check whether Ear barotrauma is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.



Related studies

How severe was Ear barotrauma and when was it recovered:

Expand to all the drugs that have ingredients of allopurinol:

Alternative drugs to, pros and cons of Allopurinol:

Common Allopurinol side effects:

Browse all side effects of Allopurinol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Ear barotrauma treatments and more:

COVID vaccines that are related to Ear barotrauma:

Common drugs associated with Ear barotrauma:

All the drugs that are associated with Ear barotrauma:

Common conditions associated with Ear barotrauma:

All the conditions that are associated with Ear barotrauma:

How the study uses the data?

The study uses data from the FDA. It is based on allopurinol (the active ingredients of Allopurinol) and Allopurinol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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