Allopurinol and Gastrointestinal inflammation - a phase IV clinical study of FDA data

Summary:

Gastrointestinal inflammation is found among people who take Allopurinol, especially for people who are male, 60+ old, have been taking the drug for < 1 month.

The phase IV clinical study analyzes which people take Allopurinol and have Gastrointestinal inflammation. It is created by eHealthMe based on reports of 150,123 people who have side effects when taking Allopurinol from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

With medical big data and AI algorithms, eHealthMe enables everyone to run phase IV clinical trial to detect adverse drug outcomes and monitor effectiveness. Our original studies have been referenced on 600+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Most recently, phase IV clinial trails for COVID 19 vaccines have been added, check here.



On May, 30, 2022

150,123 people reported to have side effects when taking Allopurinol.
Among them, 63 people (0.04%) have Gastrointestinal inflammation.


What is Allopurinol?

Allopurinol has active ingredients of allopurinol. It is often used in gout. eHealthMe is studying from 152,491 Allopurinol users for its effectiveness, alternative drugs and more.

What is Gastrointestinal inflammation?

Gastrointestinal inflammation (inflammation of stomach and intestine) is found to be associated with 759 drugs and 492 conditions by eHealthMe.

Number of Allopurinol and Gastrointestinal inflammation reports submitted per year:

Could Allopurinol cause Gastrointestinal inflammation?

Time on Allopurinol when people have Gastrointestinal inflammation *:

  • < 1 month: 83.33 %
  • 1 - 6 months: 16.67 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Gastrointestinal inflammation when taking Allopurinol *:

  • female: 42.37 %
  • male: 57.63 %

Age of people who have Gastrointestinal inflammation when taking Allopurinol *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 1.75 %
  • 30-39: 0.0 %
  • 40-49: 7.02 %
  • 50-59: 19.3 %
  • 60+: 71.93 %

Common drugs people take besides Allopurinol *:

  1. Pantoprazole: 13 people, 20.63%
  2. Aspirin: 11 people, 17.46%
  3. Prednisone: 11 people, 17.46%
  4. Levaquin: 10 people, 15.87%
  5. Revlimid: 9 people, 14.29%
  6. Amlodipine: 9 people, 14.29%
  7. Atenolol: 9 people, 14.29%
  8. Lipitor: 8 people, 12.70%
  9. Metformin: 8 people, 12.70%
  10. Lyrica: 7 people, 11.11%

Common side effects people have besides Gastrointestinal inflammation *:

  1. Haemoglobin Decreased: 18 people, 28.57%
  2. Fatigue (feeling of tiredness): 16 people, 25.40%
  3. Haematocrit Decreased: 12 people, 19.05%
  4. Diarrhea: 12 people, 19.05%
  5. Red Blood Cell Count Decreased: 12 people, 19.05%
  6. Renal Failure Chronic (long lasting kidney dysfunction): 12 people, 19.05%
  7. Thrombocytopenia (decrease of platelets in blood): 12 people, 19.05%
  8. Malaise (a feeling of general discomfort or uneasiness): 11 people, 17.46%
  9. Pain: 11 people, 17.46%
  10. Gastrointestinal Haemorrhage (bleeding gastrointestinal tract): 11 people, 17.46%

Common conditions people have *:

  1. Heart Disease: 6 people, 9.52%
  2. Crohn's Disease (condition that causes inflammation of the gastrointestinal tract): 6 people, 9.52%
  3. Primary Myelofibrosis (primary disorder of the bone marrow): 5 people, 7.94%
  4. Diarrhea: 4 people, 6.35%
  5. Multiple Myeloma (cancer of the plasma cells): 4 people, 6.35%
  6. Pain: 3 people, 4.76%
  7. Dementia Alzheimer's Type (loss of mental ability with alzheimer's symptom): 3 people, 4.76%
  8. Constipation: 3 people, 4.76%
  9. Diabetes: 3 people, 4.76%
  10. Chest Pain: 3 people, 4.76%

* Approximation only. Some reports may have incomplete information.

Do you take Allopurinol and have Gastrointestinal inflammation?

Check whether Gastrointestinal inflammation is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.



Related publications that referenced our studies

Related studies

Alternative drugs to, pros and cons of Allopurinol:

Gastrointestinal inflammation treatments and more:

COVID vaccines that are related to Gastrointestinal inflammation:

How severe was Gastrointestinal inflammation and when was it recovered:

Expand to all the drugs that have ingredients of allopurinol:

Common drugs associated with Gastrointestinal inflammation:

All the drugs that are associated with Gastrointestinal inflammation:

Common conditions associated with Gastrointestinal inflammation:

All the conditions that are associated with Gastrointestinal inflammation:

How the study uses the data?

The study uses data from the FDA. It is based on allopurinol (the active ingredients of Allopurinol) and Allopurinol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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