Who have Irritable bowel syndrome with Allopurinol - from FDA reports


Irritable bowel syndrome is found among people who take Allopurinol, especially for people who are female, 60+ old , have been taking the drug for < 1 month, also take medication Aredia, and have High blood pressure. This study is created by eHealthMe based on reports of 103,786 people who have side effects when taking Allopurinol from FDA, and is updated regularly.

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On Feb, 10, 2019

103,786 people reported to have side effects when taking Allopurinol.
Among them, 120 people (0.12%) have Irritable bowel syndrome


Number of reports submitted per year:

Could Allopurinol cause Irritable bowel syndrome?

Time on Allopurinol when people have Irritable bowel syndrome *:

  • < 1 month: 50 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 50 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Irritable bowel syndrome when taking Allopurinol *:

  • female: 71.96 %
  • male: 28.04 %

Age of people who have Irritable bowel syndrome when taking Allopurinol *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 1.06 %
  • 30-39: 4.26 %
  • 40-49: 3.19 %
  • 50-59: 41.49 %
  • 60+: 50.0 %

Top conditions involved for these people *:

  1. High Blood Pressure: 16 people, 13.33%
  2. Multiple Myeloma (cancer of the plasma cells): 15 people, 12.50%
  3. Neoplasm Malignant (cancer tumour): 15 people, 12.50%
  4. Light Chain Analysis Increased: 12 people, 10.00%
  5. Paget's Disease (disorder that involves abnormal bone destruction and regrowth, which results in deformity): 12 people, 10.00%
  6. Acne (skin problems that cause pimples): 10 people, 8.33%
  7. Pain: 10 people, 8.33%
  8. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 9 people, 7.50%
  9. Preventive Health Care: 9 people, 7.50%
  10. Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 6 people, 5.00%

Top co-used drugs for these people *:

  1. Aredia: 39 people, 32.50%
  2. Norvasc: 31 people, 25.83%
  3. Zofran: 30 people, 25.00%
  4. Clonidine: 30 people, 25.00%
  5. Zoloft: 29 people, 24.17%
  6. Acetaminophen: 29 people, 24.17%
  7. Prevacid: 29 people, 24.17%
  8. Coumadin: 28 people, 23.33%
  9. Amoxicillin: 27 people, 22.50%
  10. Ditropan Xl: 26 people, 21.67%

Top other side effects for these people *:

  1. Dizziness: 53 people, 44.17%
  2. Pain: 51 people, 42.50%
  3. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 49 people, 40.83%
  4. Anaemia (lack of blood): 48 people, 40.00%
  5. Diarrhea: 40 people, 33.33%
  6. Oedema Peripheral (superficial swelling): 39 people, 32.50%
  7. Bone Disorder: 39 people, 32.50%
  8. Sleep Apnea Syndrome: 39 people, 32.50%
  9. Stress And Anxiety: 38 people, 31.67%
  10. Injury: 38 people, 31.67%

* Approximation only. Some reports may have incomplete information.

Do you have Irritable bowel syndrome while taking Allopurinol?


You are not alone:




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Allopurinol side effects

Browse by gender and age

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+


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Compare Allopurinol to similar drugs:


What would happen?

Predict new side effects and undetected conditions when you take Allopurinol and have Irritable bowel syndrome


FDA reports used in this study



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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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