Allopurinol and Paranasal sinus hypersecretion - a phase IV clinical study of FDA data

Summary:

Paranasal sinus hypersecretion is found among people who take Allopurinol, especially for people who are male, 60+ old, have been taking the drug for < 1 month.

The phase IV clinical study analyzes which people take Allopurinol and have Paranasal sinus hypersecretion. It is created by eHealthMe based on reports of 164,051 people who have side effects when taking Allopurinol from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.



On Oct, 04, 2022

164,051 people reported to have side effects when taking Allopurinol.
Among them, 37 people (0.02%) have Paranasal sinus hypersecretion.


What is Allopurinol?

Allopurinol has active ingredients of allopurinol. It is often used in gout. eHealthMe is studying from 166,483 Allopurinol users for its effectiveness, alternative drugs and more.

What is Paranasal sinus hypersecretion?

Paranasal sinus hypersecretion is found to be associated with 704 drugs and 386 conditions by eHealthMe.

Number of Allopurinol and Paranasal sinus hypersecretion reports submitted per year:

Could Allopurinol cause Paranasal sinus hypersecretion?

Time on Allopurinol when people have Paranasal sinus hypersecretion *:

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Paranasal sinus hypersecretion when taking Allopurinol *:

  • female: 48.57 %
  • male: 51.43 %

Age of people who have Paranasal sinus hypersecretion when taking Allopurinol *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 3.7 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 22.22 %
  • 60+: 74.07 %

Common drugs people take besides Allopurinol *:

  1. Venclexta: 9 people, 24.32%
  2. Vitamin B12: 7 people, 18.92%
  3. Vitamin D3: 6 people, 16.22%
  4. Metformin: 6 people, 16.22%
  5. Imbruvica: 5 people, 13.51%
  6. Claritin: 5 people, 13.51%
  7. Vitamin C: 5 people, 13.51%
  8. Curcumin: 4 people, 10.81%
  9. Lasix: 4 people, 10.81%
  10. Tylenol: 4 people, 10.81%

Common side effects people have besides Paranasal sinus hypersecretion *:

  1. Fatigue (feeling of tiredness): 12 people, 32.43%
  2. Cough: 10 people, 27.03%
  3. Headache (pain in head): 9 people, 24.32%
  4. Dizziness: 9 people, 24.32%
  5. Fall: 8 people, 21.62%
  6. Weakness: 7 people, 18.92%
  7. Diarrhea: 7 people, 18.92%
  8. Insomnia (sleeplessness): 6 people, 16.22%
  9. Head Injury: 6 people, 16.22%
  10. Rashes (redness): 6 people, 16.22%

Common conditions people have *:

  1. Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 11 people, 29.73%
  2. High Blood Pressure: 7 people, 18.92%
  3. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 5 people, 13.51%
  4. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 13.51%
  5. Arthritis (form of joint disorder that involves inflammation of one or more joints): 4 people, 10.81%
  6. B-Cell Small Lymphocytic Lymphoma (blood cancer affecting b cells): 4 people, 10.81%
  7. Crohn's Disease (condition that causes inflammation of the gastrointestinal tract): 3 people, 8.11%
  8. Glucose Tolerance Impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis): 3 people, 8.11%
  9. Pain: 3 people, 8.11%
  10. Abdominal Discomfort: 3 people, 8.11%

* Approximation only. Some reports may have incomplete information.

Do you take Allopurinol and have Paranasal sinus hypersecretion?

Check whether Paranasal sinus hypersecretion is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.



Related studies

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Common Allopurinol side effects:

Browse all side effects of Allopurinol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Paranasal sinus hypersecretion treatments and more:

COVID vaccines that are related to Paranasal sinus hypersecretion:

Common drugs associated with Paranasal sinus hypersecretion:

All the drugs that are associated with Paranasal sinus hypersecretion:

Common conditions associated with Paranasal sinus hypersecretion:

All the conditions that are associated with Paranasal sinus hypersecretion:

How the study uses the data?

The study uses data from the FDA. It is based on allopurinol (the active ingredients of Allopurinol) and Allopurinol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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