Allopurinol and Tooth loss - a phase IV clinical study of FDA data
Summary:
We study 178,791 people who have side effects when taking Allopurinol. Tooth loss is found, especially among people who are female, 60+ old, have been taking the drug for < 1 month, also take Zometa and have Pain.
The phase IV clinical study analyzes which people take Allopurinol and have Tooth loss. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
178,791 people reported to have side effects when taking Allopurinol.
Among them, 176 people (0.1%) have Tooth loss.
What is Allopurinol?
Allopurinol has active ingredients of allopurinol. It is used in gout. Currently, eHealthMe is studying from 181,418 Allopurinol users.
What is Tooth loss?
Tooth loss is found to be associated with 1,739 drugs and 926 conditions by eHealthMe. Currently, we are studying 32,408 people who have Tooth loss.
Number of Allopurinol and Tooth loss reports submitted per year:

Time on Allopurinol when people have Tooth loss *:
Gender of people who have Tooth loss when taking Allopurinol*:
Age of people who have Tooth loss when taking Allopurinol *:
Common drugs people take besides Allopurinol *:
Common side effects people have besides Tooth loss *:
Common conditions people have *:
* Approximation only. Some reports may have incomplete information.
Do you take Allopurinol and have Tooth loss?
Check whether Tooth loss is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
Allopurinol side effects by duration, gender and age:
- Allopurinol side effects (181,418 reports)
Tooth loss treatments and more:
- Tooth loss (32,408 reports)
Common drugs associated with Tooth loss:
- Truvada: 12,240 reports
- Atripla: 7,948 reports
- Viread: 7,154 reports
- Genvoya: 2,613 reports
- Descovy: 2,535 reports
- Zometa: 1,855 reports
- Fosamax: 1,614 reports
- Oxycontin: 1,357 reports
- Aredia: 939 reports
- Aspirin: 927 reports
All the drugs that are associated with Tooth loss:
- Tooth loss (1,739 drugs)
Common conditions associated with Tooth loss:
- Hiv infection: 16,667 reports
- Osteoporosis: 1,627 reports
- Pain: 1,034 reports
- Rheumatoid arthritis: 696 reports
- High blood pressure: 596 reports
All the conditions that are associated with Tooth loss:
- Tooth loss (926 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on allopurinol (the active ingredients of Allopurinol) and Allopurinol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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