Allopurinol and Uveitis - a phase IV clinical study of FDA data


Uveitis is found among people who take Allopurinol, especially for people who are male, 50-59 old, have been taking the drug for < 1 month.

The phase IV clinical study analyzes which people take Allopurinol and have Uveitis. It is created by eHealthMe based on reports of 150,123 people who have side effects when taking Allopurinol from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

With medical big data and AI algorithms, eHealthMe enables everyone to run phase IV clinical trial to detect adverse drug outcomes and monitor effectiveness. Our original studies have been referenced on 600+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Most recently, phase IV clinial trails for COVID 19 vaccines have been added, check here.

On May, 10, 2022

150,123 people reported to have side effects when taking Allopurinol.
Among them, 67 people (0.04%) have Uveitis.

What is Allopurinol?

Allopurinol has active ingredients of allopurinol. It is often used in gout. eHealthMe is studying from 152,518 Allopurinol users for its effectiveness, alternative drugs and more.

What is Uveitis?

Uveitis (inflammation of the uvea) is found to be associated with 1,593 drugs and 1,301 conditions by eHealthMe.

Number of Allopurinol and Uveitis reports submitted per year:

Could Allopurinol cause Uveitis?

Time on Allopurinol when people have Uveitis *:

  • < 1 month: 33.33 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 33.33 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 33.33 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Uveitis when taking Allopurinol *:

  • female: 29.03 %
  • male: 70.97 %

Age of people who have Uveitis when taking Allopurinol *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 3.57 %
  • 40-49: 16.07 %
  • 50-59: 48.21 %
  • 60+: 32.14 %

Common drugs people take besides Allopurinol *:

  1. Ambien: 17 people, 25.37%
  2. Zometa: 17 people, 25.37%
  3. Mydriacyl: 16 people, 23.88%
  4. Amoxicillin: 15 people, 22.39%
  5. Zovirax: 15 people, 22.39%
  6. Neurontin: 14 people, 20.90%
  7. Acetaminophen: 14 people, 20.90%
  8. Toradol: 14 people, 20.90%
  9. Lisinopril: 13 people, 19.40%
  10. Magnesium Sulfate: 13 people, 19.40%

Common side effects people have besides Uveitis *:

  1. Joint Pain: 23 people, 34.33%
  2. Vision Blurred: 20 people, 29.85%
  3. Eye Pain: 18 people, 26.87%
  4. Pain: 18 people, 26.87%
  5. Lacrimation Increased: 17 people, 25.37%
  6. Infection: 17 people, 25.37%
  7. Stress And Anxiety: 17 people, 25.37%
  8. Emotional Distress: 17 people, 25.37%
  9. Eye Irritation: 17 people, 25.37%
  10. Ocular Hyperaemia (an abnormally large amount of blood in eye): 17 people, 25.37%

Common conditions people have *:

  1. Metastases To Bone (cancer spreads to bone): 16 people, 23.88%
  2. Cuts And Puncture Wounds: 13 people, 19.40%
  3. High Blood Pressure: 7 people, 10.45%
  4. Ankylosing Spondylitis (type of arthritis affecting the spine): 4 people, 5.97%
  5. Back Pain: 4 people, 5.97%
  6. Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 4 people, 5.97%
  7. Hyperuricaemia (level of uric acid in the blood that is abnormally high): 4 people, 5.97%
  8. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 4.48%
  9. Cardiac Disorder: 3 people, 4.48%
  10. Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 3 people, 4.48%

* Approximation only. Some reports may have incomplete information.

Do you take Allopurinol and have Uveitis?

Check whether Uveitis is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

Alternative drugs to, pros and cons of Allopurinol:

Uveitis treatments and more:

COVID vaccines that are related to Uveitis:

How severe was Uveitis and when was it recovered:

Expand to all the drugs that have ingredients of allopurinol:

Common drugs associated with Uveitis:

All the drugs that are associated with Uveitis:

Common conditions associated with Uveitis:

All the conditions that are associated with Uveitis:

How the study uses the data?

The study uses data from the FDA. It is based on allopurinol (the active ingredients of Allopurinol) and Allopurinol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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