Alphagan and Allergic rhinitis - a phase IV clinical study of FDA data


Allergic rhinitis is found among people who take Alphagan, especially for people who are female, 60+ old.

The phase IV clinical study analyzes which people take Alphagan and have Allergic rhinitis. It is created by eHealthMe based on reports of 8,635 people who have side effects when taking Alphagan from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

With medical big data and AI algorithms, eHealthMe enables everyone to run phase IV clinical trial to detect adverse drug outcomes and monitor effectiveness. Our original studies have been referenced on 600+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Most recently, phase IV clinial trails for COVID 19 vaccines have been added, check here.

On Jul, 04, 2022

8,635 people reported to have side effects when taking Alphagan.
Among them, 13 people (0.15%) have Allergic rhinitis.

What is Alphagan?

Alphagan has active ingredients of brimonidine tartrate. It is often used in glaucoma. eHealthMe is studying from 8,807 Alphagan users for its effectiveness, alternative drugs and more.

What is Allergic rhinitis?

Allergic rhinitis is found to be associated with 1,861 drugs and 1,176 conditions by eHealthMe.

Number of Alphagan and Allergic rhinitis reports submitted per year:

Could Alphagan cause Allergic rhinitis?

Gender of people who have Allergic rhinitis when taking Alphagan *:

  • female: 76.92 %
  • male: 23.08 %

Age of people who have Allergic rhinitis when taking Alphagan *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 15.38 %
  • 60+: 84.62 %

Common drugs people take besides Alphagan *:

  1. Albuterol: 7 people, 53.85%
  2. Xalatan: 7 people, 53.85%
  3. Arimidex: 7 people, 53.85%
  4. Accupril: 6 people, 46.15%
  5. Paxil: 6 people, 46.15%
  6. Allegra: 6 people, 46.15%
  7. Aredia: 6 people, 46.15%
  8. Vicodin: 6 people, 46.15%
  9. Benadryl: 6 people, 46.15%
  10. Cortisone Acetate: 6 people, 46.15%

Common side effects people have besides Allergic rhinitis *:

  1. Fatigue (feeling of tiredness): 10 people, 76.92%
  2. Muscle Spasms (muscle contraction): 9 people, 69.23%
  3. Fever: 8 people, 61.54%
  4. Chest Pain: 8 people, 61.54%
  5. Cellulitis (infection under the skin): 7 people, 53.85%
  6. Sinus Tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node): 7 people, 53.85%
  7. Pain In Jaw: 7 people, 53.85%
  8. Dizziness: 7 people, 53.85%
  9. Joint Pain: 7 people, 53.85%
  10. Oedema Peripheral (superficial swelling): 7 people, 53.85%

Common conditions people have *:

  1. Metastases To Bone (cancer spreads to bone): 6 people, 46.15%
  2. Osteoporosis (bones weak and more likely to break): 4 people, 30.77%
  3. Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 2 people, 15.38%
  4. Breast Cancer Metastatic: 2 people, 15.38%
  5. Nasal Congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 1 person, 7.69%
  6. Eye Infection: 1 person, 7.69%
  7. Breathing Difficulty: 1 person, 7.69%
  8. Atrial Tachycardia (rhythm disturbance that arises in the atria): 1 person, 7.69%
  9. Athlete's Foot (a fungal infection affecting the skin between the toes): 1 person, 7.69%
  10. Arthritis (form of joint disorder that involves inflammation of one or more joints): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Alphagan and have Allergic rhinitis?

Check whether Allergic rhinitis is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

Alternative drugs to, pros and cons of Alphagan:

Allergic rhinitis treatments and more:

COVID vaccines that are related to Allergic rhinitis:

How severe was Allergic rhinitis and when was it recovered:

Expand to all the drugs that have ingredients of brimonidine tartrate:

Common drugs associated with Allergic rhinitis:

All the drugs that are associated with Allergic rhinitis:

Common conditions associated with Allergic rhinitis:

All the conditions that are associated with Allergic rhinitis:

How the study uses the data?

The study uses data from the FDA. It is based on brimonidine tartrate (the active ingredients of Alphagan) and Alphagan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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