Alrex and Dupuytren's contracture - a phase IV clinical study of FDA data


Dupuytren's contracture is reported only by a few people who take Alrex.

The phase IV clinical study analyzes which people take Alrex and have Dupuytren's contracture. It is created by eHealthMe based on reports of 562 people who have side effects while taking Alrex from the FDA, and is updated regularly.

With medical big data and AI algorithms, eHealthMe enables everyone to run phase IV clinical trial to detect adverse drug outcomes and monitor effectiveness. Our original studies have been referenced on 600+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Most recently, phase IV clinial trails for COVID 19 vaccines have been added, check here.

On Jun, 30, 2022

562 people reported to have side effects when taking Alrex.
Among them, 2 people (0.36%) have Dupuytren's contracture.

What is Alrex?

Alrex has active ingredients of loteprednol etabonate. eHealthMe is studying from 573 Alrex users for its effectiveness, alternative drugs and more.

What is Dupuytren's contracture?

Dupuytren's contracture (thickening of the fibrous tissue layer underneath the skin of the palm and fingers) is found to be associated with 435 drugs and 194 conditions by eHealthMe.

Number of Alrex and Dupuytren's contracture reports submitted per year:

Could Alrex cause Dupuytren's contracture?

Time on Alrex when people have Dupuytren's contracture *:

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Dupuytren's contracture when taking Alrex *:

  • female: 100 %
  • male: 0.0 %

Common drugs people take besides Alrex *:

  1. Zyrtec: 2 people, 100.00%
  2. Zoloft: 2 people, 100.00%
  3. Nexium: 2 people, 100.00%
  4. Myrbetriq: 2 people, 100.00%
  5. Macrobid: 2 people, 100.00%
  6. Krill Oil: 2 people, 100.00%
  7. Humira: 2 people, 100.00%
  8. Horizant: 2 people, 100.00%
  9. Flexeril: 2 people, 100.00%
  10. Estring: 2 people, 100.00%

Common side effects people have besides Dupuytren's contracture *:

  1. Urinary Incontinence (inability to control the flow of urine and involuntary urination): 2 people, 100.00%
  2. Serum Ferritin Decreased: 2 people, 100.00%
  3. Pulmonary Mass: 2 people, 100.00%
  4. Joint Stiffness: 2 people, 100.00%
  5. High Blood Pressure: 2 people, 100.00%
  6. High Blood Cholesterol: 2 people, 100.00%
  7. Hiatal Hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm): 2 people, 100.00%
  8. Diarrhea: 2 people, 100.00%
  9. Breathing Sounds - Abnormal (Stridor): 2 people, 100.00%

Common conditions people have *:

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 100.00%
  2. Hiatal Hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm): 2 people, 100.00%

* Approximation only. Some reports may have incomplete information.

Do you take Alrex and have Dupuytren's contracture?

Check whether Dupuytren's contracture is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

Alternative drugs to, pros and cons of Alrex:

Dupuytren's contracture treatments and more:

COVID vaccines that are related to Dupuytren's contracture:

How severe was Dupuytren's contracture and when was it recovered:

Expand to all the drugs that have ingredients of loteprednol etabonate:

Common drugs associated with Dupuytren's contracture:

All the drugs that are associated with Dupuytren's contracture:

All the conditions that are associated with Dupuytren's contracture:

How the study uses the data?

The study uses data from the FDA. It is based on loteprednol etabonate (the active ingredients of Alrex) and Alrex (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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