Altace and Ocular icterus - a phase IV clinical study of FDA data
Summary:
Ocular icterus is found among people who take Altace, especially for people who are male, 50-59 old, have been taking the drug for 1 - 6 months.
The phase IV clinical study analyzes which people take Altace and have Ocular icterus. It is created by eHealthMe based on reports of 22,516 people who have side effects when taking Altace from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
22,516 people reported to have side effects when taking Altace.
Among them, 40 people (0.18%) have Ocular icterus.
What is Altace?
Altace has active ingredients of ramipril. It is often used in high blood pressure. eHealthMe is studying from 23,109 Altace users for its effectiveness, alternative drugs and more.
What is Ocular icterus?
Ocular icterus (presence of jaundice seen in the sclera of the eye) is found to be associated with 1,208 drugs and 750 conditions by eHealthMe.
Number of Altace and Ocular icterus reports submitted per year:

Time on Altace when people have Ocular icterus *:
- < 1 month: 0.0 %
- 1 - 6 months: 100 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
Gender of people who have Ocular icterus when taking Altace *:
- female: 27.5 %
- male: 72.5 %
Age of people who have Ocular icterus when taking Altace *:
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 2.5 %
- 40-49: 2.5 %
- 50-59: 85.0 %
- 60+: 10.0 %
Common drugs people take besides Altace *:
- Lantus: 28 people, 70.00%
- Asa: 23 people, 57.50%
- Amlodipine: 18 people, 45.00%
- Humulin R: 11 people, 27.50%
- Crestor: 11 people, 27.50%
- Sandostatin: 10 people, 25.00%
- Norvasc: 9 people, 22.50%
- Lasix: 8 people, 20.00%
- Aspirin: 7 people, 17.50%
- Insulin: 7 people, 17.50%
Common side effects people have besides Ocular icterus *:
- Discomfort: 30 people, 75.00%
- Jaundice - Yellow Skin (a yellowish pigmentation of the skin): 30 people, 75.00%
- Pain: 30 people, 75.00%
- Blood Pressure Systolic Increased: 29 people, 72.50%
- Weight Decreased: 29 people, 72.50%
- Yellow Skin: 28 people, 70.00%
- Post Procedural Complication: 28 people, 70.00%
- Bile Duct Obstruction (blockage in the tubes that carry bile from the liver to the gallbladder): 28 people, 70.00%
- Blood Glucose Decreased: 28 people, 70.00%
- Blood Pressure Diastolic Decreased: 28 people, 70.00%
Common conditions people have *:
- Carcinoid Tumor: 28 people, 70.00%
- Nuclear Magnetic Resonance Imaging Abdominal: 5 people, 12.50%
- Bone Neoplasm Malignant (cancer of bone): 2 people, 5.00%
- Myasthenia Gravis (a chronic condition that causes muscles to tire and weaken easily): 1 person, 2.50%
- Insomnia (sleeplessness): 1 person, 2.50%
- Diabetes: 1 person, 2.50%
- Birth Control: 1 person, 2.50%
* Approximation only. Some reports may have incomplete information.
Do you take Altace and have Ocular icterus?
Check whether Ocular icterus is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
How severe was Ocular icterus and when was it recovered:
Expand to all the drugs that have ingredients of ramipril:
- Ocular icterus and drugs with ingredients of ramipril (110 reports)
Alternative drugs to, pros and cons of Altace:
- Altace (23,109 reports)
Common Altace side effects:
- Heart attack: 1,703 reports
- High blood pressure: 1,664 reports
- Fatigue (feeling of tiredness): 1,635 reports
- Weakness: 1,574 reports
- Breathing difficulty: 1,531 reports
- Pain: 1,523 reports
Browse all side effects of Altace:
a b c d e f g h i j k l m n o p q r s t u v w x y zOcular icterus treatments and more:
- Ocular icterus (4,720 reports)
COVID vaccines that are related to Ocular icterus:
- Ocular icterus in Moderna COVID Vaccine
- Ocular icterus in Pfizer BioNTech Covid Vaccine
- Ocular icterus in Johnson and Johnson Covid Vaccine
Common drugs associated with Ocular icterus:
- Aspirin: 258 reports
- Prednisone: 205 reports
- Ibu: 156 reports
- Ibuprofen: 155 reports
- Omeprazole: 155 reports
- Furosemide: 153 reports
- Amlodipine: 147 reports
- Pantoprazole: 123 reports
- Humira: 120 reports
- Soliris: 116 reports
All the drugs that are associated with Ocular icterus:
- Ocular icterus (1,208 drugs)
Common conditions associated with Ocular icterus:
- Multiple sclerosis: 242 reports
- High blood pressure: 227 reports
- Hiv infection: 222 reports
- Hepatitis c: 169 reports
- Pain: 123 reports
All the conditions that are associated with Ocular icterus:
- Ocular icterus (750 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on ramipril (the active ingredients of Altace) and Altace (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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