Altace and Ocular icterus - a phase IV clinical study of FDA data


Ocular icterus is found among people who take Altace, especially for people who are male, 50-59 old, have been taking the drug for 1 - 6 months.

The phase IV clinical study analyzes which people take Altace and have Ocular icterus. It is created by eHealthMe based on reports of 22,516 people who have side effects when taking Altace from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Mar, 28, 2023

22,516 people reported to have side effects when taking Altace.
Among them, 40 people (0.18%) have Ocular icterus.

What is Altace?

Altace has active ingredients of ramipril. It is often used in high blood pressure. eHealthMe is studying from 23,109 Altace users for its effectiveness, alternative drugs and more.

What is Ocular icterus?

Ocular icterus (presence of jaundice seen in the sclera of the eye) is found to be associated with 1,208 drugs and 750 conditions by eHealthMe.

Number of Altace and Ocular icterus reports submitted per year:

Could Altace cause Ocular icterus?

Time on Altace when people have Ocular icterus *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 100 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Ocular icterus when taking Altace *:

  • female: 27.5 %
  • male: 72.5 %

Age of people who have Ocular icterus when taking Altace *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 2.5 %
  • 40-49: 2.5 %
  • 50-59: 85.0 %
  • 60+: 10.0 %

Common drugs people take besides Altace *:

  1. Lantus: 28 people, 70.00%
  2. Asa: 23 people, 57.50%
  3. Amlodipine: 18 people, 45.00%
  4. Humulin R: 11 people, 27.50%
  5. Crestor: 11 people, 27.50%
  6. Sandostatin: 10 people, 25.00%
  7. Norvasc: 9 people, 22.50%
  8. Lasix: 8 people, 20.00%
  9. Aspirin: 7 people, 17.50%
  10. Insulin: 7 people, 17.50%

Common side effects people have besides Ocular icterus *:

  1. Discomfort: 30 people, 75.00%
  2. Jaundice - Yellow Skin (a yellowish pigmentation of the skin): 30 people, 75.00%
  3. Pain: 30 people, 75.00%
  4. Blood Pressure Systolic Increased: 29 people, 72.50%
  5. Weight Decreased: 29 people, 72.50%
  6. Yellow Skin: 28 people, 70.00%
  7. Post Procedural Complication: 28 people, 70.00%
  8. Bile Duct Obstruction (blockage in the tubes that carry bile from the liver to the gallbladder): 28 people, 70.00%
  9. Blood Glucose Decreased: 28 people, 70.00%
  10. Blood Pressure Diastolic Decreased: 28 people, 70.00%

Common conditions people have *:

  1. Carcinoid Tumor: 28 people, 70.00%
  2. Nuclear Magnetic Resonance Imaging Abdominal: 5 people, 12.50%
  3. Bone Neoplasm Malignant (cancer of bone): 2 people, 5.00%
  4. Myasthenia Gravis (a chronic condition that causes muscles to tire and weaken easily): 1 person, 2.50%
  5. Insomnia (sleeplessness): 1 person, 2.50%
  6. Diabetes: 1 person, 2.50%
  7. Birth Control: 1 person, 2.50%

* Approximation only. Some reports may have incomplete information.

Do you take Altace and have Ocular icterus?

Check whether Ocular icterus is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Ocular icterus and when was it recovered:

Expand to all the drugs that have ingredients of ramipril:

Alternative drugs to, pros and cons of Altace:

Common Altace side effects:

Browse all side effects of Altace:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Ocular icterus treatments and more:

COVID vaccines that are related to Ocular icterus:

Common drugs associated with Ocular icterus:

All the drugs that are associated with Ocular icterus:

Common conditions associated with Ocular icterus:

All the conditions that are associated with Ocular icterus:

How the study uses the data?

The study uses data from the FDA. It is based on ramipril (the active ingredients of Altace) and Altace (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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