Amiodarone hydrochloride and Gastrointestinal inflammation - a phase IV clinical study of FDA data

Summary:

Gastrointestinal inflammation is found among people who take Amiodarone hydrochloride, especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months.

The phase IV clinical study analyzes which people take Amiodarone hydrochloride and have Gastrointestinal inflammation. It is created by eHealthMe based on reports of 6,115 people who have side effects when taking Amiodarone hydrochloride from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

With medical big data and AI algorithms, eHealthMe enables everyone to run phase IV clinical trial to detect adverse drug outcomes and monitor effectiveness. Our original studies have been referenced on 600+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Most recently, phase IV clinial trails for COVID 19 vaccines have been added, check here.

On Jun, 30, 2022

6,115 people reported to have side effects when taking Amiodarone hydrochloride.
Among them, 7 people (0.11%) have Gastrointestinal inflammation.

What is Amiodarone hydrochloride?

Amiodarone hydrochloride has active ingredients of amiodarone hydrochloride. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 6,790 Amiodarone hydrochloride users for its effectiveness, alternative drugs and more.

What is Gastrointestinal inflammation?

Gastrointestinal inflammation (inflammation of stomach and intestine) is found to be associated with 759 drugs and 492 conditions by eHealthMe.

Number of Amiodarone hydrochloride and Gastrointestinal inflammation reports submitted per year:

Could Amiodarone hydrochloride cause Gastrointestinal inflammation?

Time on Amiodarone hydrochloride when people have Gastrointestinal inflammation *:

Gender of people who have Gastrointestinal inflammation when taking Amiodarone hydrochloride *:

female: 20 %
male: 80 %

Age of people who have Gastrointestinal inflammation when taking Amiodarone hydrochloride *:

Common drugs people take besides Amiodarone hydrochloride *:

Levothyroxine Sodium: 3 people, 42.86%
Simvastatin: 3 people, 42.86%
Prednisone: 3 people, 42.86%
Ondansetron: 2 people, 28.57%
Neulasta: 2 people, 28.57%
Cyclophosphamide: 2 people, 28.57%
Doxorubicin Hydrochloride: 1 person, 14.29%
Amlodipine Besylate: 1 person, 14.29%
Aspirin: 1 person, 14.29%
Bisoprolol Fumarate: 1 person, 14.29%

Common side effects people have besides Gastrointestinal inflammation *:

Diarrhea: 4 people, 57.14%
Palmar-Plantar Erythrodysaesthesia Syndrome (hand-foot syndrome): 4 people, 57.14%
Dehydration (dryness resulting from the removal of water): 4 people, 57.14%
Stomatitis (inflammation of mucous membrane of mouth): 4 people, 57.14%
Pain Of Skin: 4 people, 57.14%
Conduction Disorder (serious disorder of the heart not responses proper to impulses): 2 people, 28.57%
Ventricular Tachyarrhythmia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart): 2 people, 28.57%
Nausea (feeling of having an urge to vomit): 2 people, 28.57%
Nausea And Vomiting: 2 people, 28.57%
Bradyarrhythmia (heart slowness): 2 people, 28.57%

Common conditions people have *:

Tachyarrhythmia (disturbance of the heart rhythm in which the heart rate is abnormally increased): 4 people, 57.14%
Hyperthyroidism (over activity of the thyroid gland): 4 people, 57.14%
Hyperlipidaemia (presence of excess lipids in the blood): 4 people, 57.14%
High Blood Pressure: 4 people, 57.14%
Burkitt Lymphoma (cancer of the lymphatic system): 4 people, 57.14%
Type 2 Diabetes: 1 person, 14.29%

* Approximation only. Some reports may have incomplete information.

Do you take Amiodarone hydrochloride and have Gastrointestinal inflammation?

Check whether Gastrointestinal inflammation is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Schwerd T, Pandey S, Yang HT, Bagola K, Jameson E, Jung J, Lachmann RH, Shah N, Patel SY, Booth C, Runz H, "Impaired antibacterial autophagy links granulomatous intestinal inflammation in Niemann–Pick disease type C1 and XIAP deficiency with NOD2 variants in Crohn9s disease", Gut, 2016 Mar .
Tesic D, Kostic M, Paunovic D, Jankovic SM, "Analysis of the cost–effectiveness of dronedarone versus amiodarone, propafenone, and sotalol in patients with atrial fibrillation: results for Serbia", Kardiologia Polska (Polish Heart Journal), 2016 Jan .
Kim DJ, Lee SC, Park GS, Kim GJ, Hwang WT, Lee CS, Lee MH, Hahn DH, Koh HC, "Amiodarone Induced Multiorgan Toxicity in a Patient of Hypertrophic Cardiomyopathy With Atrial Fibrillation", Journal of the Korean Geriatrics Society, 2013 Dec .

Related studies

Alternative drugs to, pros and cons of Amiodarone hydrochloride:

Amiodarone hydrochloride (6,790 reports)

Gastrointestinal inflammation treatments and more:

Gastrointestinal inflammation (6,885 reports)

COVID vaccines that are related to Gastrointestinal inflammation:

How severe was Gastrointestinal inflammation and when was it recovered:

Gastrointestinal inflammation in Amiodarone hydrochloride

Expand to all the drugs that have ingredients of amiodarone hydrochloride:

Gastrointestinal inflammation and drugs with ingredients of amiodarone hydrochloride

Common drugs associated with Gastrointestinal inflammation:

How the study uses the data?

The study uses data from the FDA. It is based on amiodarone hydrochloride (the active ingredients of Amiodarone hydrochloride) and Amiodarone hydrochloride (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.