Amitriptyline hydrochloride and Paranasal sinus hypersecretion - a phase IV clinical study of FDA data


Paranasal sinus hypersecretion is reported only by a few people who take Amitriptyline Hydrochloride.

The phase IV clinical study analyzes which people take Amitriptyline hydrochloride and have Paranasal sinus hypersecretion. It is created by eHealthMe based on reports of 11,507 people who have side effects while taking Amitriptyline hydrochloride from the FDA, and is updated regularly.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Oct, 04, 2022

11,507 people reported to have side effects when taking Amitriptyline hydrochloride.
Among them, 3 people (0.03%) have Paranasal sinus hypersecretion.

What is Amitriptyline hydrochloride?

Amitriptyline hydrochloride has active ingredients of amitriptyline hydrochloride. It is often used in migraine. eHealthMe is studying from 14,695 Amitriptyline hydrochloride users for its effectiveness, alternative drugs and more.

What is Paranasal sinus hypersecretion?

Paranasal sinus hypersecretion is found to be associated with 704 drugs and 386 conditions by eHealthMe.

Number of Amitriptyline hydrochloride and Paranasal sinus hypersecretion reports submitted per year:

Could Amitriptyline hydrochloride cause Paranasal sinus hypersecretion?

Gender of people who have Paranasal sinus hypersecretion when taking Amitriptyline hydrochloride *:

  • female: 100 %
  • male: 0.0 %

Age of people who have Paranasal sinus hypersecretion when taking Amitriptyline hydrochloride *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 100 %

Common drugs people take besides Amitriptyline hydrochloride *:

  1. Zyloprim: 3 people, 100.00%
  2. Klor-Con: 3 people, 100.00%
  3. Hydrochlorothiazide: 3 people, 100.00%
  4. Furosemide: 3 people, 100.00%
  5. Flonase: 3 people, 100.00%
  6. Feldene: 3 people, 100.00%
  7. Elavil: 3 people, 100.00%
  8. Effexor: 3 people, 100.00%
  9. Crestor: 3 people, 100.00%
  10. Cozaar: 3 people, 100.00%

Common side effects people have besides Paranasal sinus hypersecretion *:

  1. Weakness: 3 people, 100.00%
  2. Glucose Tolerance Impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis): 3 people, 100.00%
  3. Diverticulum Intestinal (a pouch that is attached to the first part of the small intestine): 3 people, 100.00%
  4. Dyskinesia Oesophageal (abnormality or impairment of voluntary movement of oesophageal): 3 people, 100.00%
  5. Emotional Distress: 3 people, 100.00%
  6. Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs): 3 people, 100.00%
  7. Encephalomalacia (localized softening of the brain substance, due to haemorrhage or inflammation): 3 people, 100.00%
  8. Facet Joint Syndrome (problem with movement of the facet joints of the spine): 3 people, 100.00%
  9. Fainting (loss of consciousness and postural tone): 3 people, 100.00%
  10. Foot Deformity (functional disability of foot): 3 people, 100.00%

Common conditions people have *:

  1. Neoplasm Malignant (cancer tumour): 3 people, 100.00%
  2. Metastases To Spine (cancer spreads to spine): 3 people, 100.00%
  3. Lung Neoplasm (tumour of lung): 3 people, 100.00%
  4. Calcium Deficiency (lack of calcium): 3 people, 100.00%
  5. Trigeminal Neuralgia (a painful condition of the nerve responsible for most facial sensation): 1 person, 33.33%
  6. Pain: 1 person, 33.33%

* Approximation only. Some reports may have incomplete information.

Do you take Amitriptyline hydrochloride and have Paranasal sinus hypersecretion?

Check whether Paranasal sinus hypersecretion is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

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How severe was Paranasal sinus hypersecretion and when was it recovered:

Expand to all the drugs that have ingredients of amitriptyline hydrochloride:

Alternative drugs to, pros and cons of Amitriptyline hydrochloride:

Common Amitriptyline hydrochloride side effects:

Browse all side effects of Amitriptyline hydrochloride:

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Paranasal sinus hypersecretion treatments and more:

COVID vaccines that are related to Paranasal sinus hypersecretion:

Common drugs associated with Paranasal sinus hypersecretion:

All the drugs that are associated with Paranasal sinus hypersecretion:

Common conditions associated with Paranasal sinus hypersecretion:

All the conditions that are associated with Paranasal sinus hypersecretion:

How the study uses the data?

The study uses data from the FDA. It is based on amitriptyline hydrochloride (the active ingredients of Amitriptyline hydrochloride) and Amitriptyline hydrochloride (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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