Amlodipine besylate and Dupuytren's contracture - a phase IV clinical study of FDA data

Summary:

Dupuytren's contracture is reported only by a few people who take Amlodipine Besylate.

The phase IV clinical study analyzes which people take Amlodipine besylate and have Dupuytren's contracture. It is created by eHealthMe based on reports of 44,678 people who have side effects while taking Amlodipine besylate from the FDA, and is updated regularly.

With medical big data and AI algorithms, eHealthMe enables everyone to run phase IV clinical trial to detect adverse drug outcomes and monitor effectiveness. Our original studies have been referenced on 600+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Most recently, phase IV clinial trails for COVID 19 vaccines have been added, check here.



On Jun, 30, 2022

44,678 people reported to have side effects when taking Amlodipine besylate.
Among them, 4 people (0.01%) have Dupuytren's contracture.


What is Amlodipine besylate?

Amlodipine besylate has active ingredients of amlodipine besylate. It is often used in high blood pressure. eHealthMe is studying from 48,263 Amlodipine besylate users for its effectiveness, alternative drugs and more.

What is Dupuytren's contracture?

Dupuytren's contracture (thickening of the fibrous tissue layer underneath the skin of the palm and fingers) is found to be associated with 435 drugs and 194 conditions by eHealthMe.

Number of Amlodipine besylate and Dupuytren's contracture reports submitted per year:

Could Amlodipine besylate cause Dupuytren's contracture?

Time on Amlodipine besylate when people have Dupuytren's contracture *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 100 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Dupuytren's contracture when taking Amlodipine besylate *:

  • female: 25 %
  • male: 75 %

Age of people who have Dupuytren's contracture when taking Amlodipine besylate *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 75 %
  • 60+: 25 %

Common drugs people take besides Amlodipine besylate *:

  1. Ocrevus: 2 people, 50.00%
  2. Trileptal: 2 people, 50.00%
  3. Sertraline: 2 people, 50.00%
  4. Zyrtec: 1 person, 25.00%
  5. Ativan: 1 person, 25.00%
  6. Colace: 1 person, 25.00%
  7. Effexor: 1 person, 25.00%
  8. Enbrel: 1 person, 25.00%
  9. Klonopin: 1 person, 25.00%
  10. Lamictal: 1 person, 25.00%

Common side effects people have besides Dupuytren's contracture *:

  1. Wound Infection: 2 people, 50.00%
  2. Pain In Extremity: 2 people, 50.00%
  3. Impaired Healing: 2 people, 50.00%
  4. Intervertebral Disc Degeneration (spinal disc degeneration): 2 people, 50.00%
  5. Muscle Spasms (muscle contraction): 2 people, 50.00%
  6. Bladder Spasm: 2 people, 50.00%
  7. Rickets (softening of bones): 2 people, 50.00%
  8. Urinary Tract Infection: 2 people, 50.00%
  9. Weakness: 2 people, 50.00%
  10. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 1 person, 25.00%

Common conditions people have *:

  1. Primary Progressive Multiple Sclerosis (primary progressive inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 2 people, 50.00%
  2. Pain: 2 people, 50.00%
  3. Muscle Spasms (muscle contraction): 2 people, 50.00%
  4. Depression: 2 people, 50.00%
  5. Back Pain: 2 people, 50.00%
  6. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 25.00%
  7. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 1 person, 25.00%
  8. Ankylosing Spondylitis (type of arthritis affecting the spine): 1 person, 25.00%

* Approximation only. Some reports may have incomplete information.

Do you take Amlodipine besylate and have Dupuytren's contracture?

Check whether Dupuytren's contracture is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.



Related studies

Alternative drugs to, pros and cons of Amlodipine besylate:

Dupuytren's contracture treatments and more:

COVID vaccines that are related to Dupuytren's contracture:

How severe was Dupuytren's contracture and when was it recovered:

Expand to all the drugs that have ingredients of amlodipine besylate:

Common drugs associated with Dupuytren's contracture:

All the drugs that are associated with Dupuytren's contracture:

All the conditions that are associated with Dupuytren's contracture:

How the study uses the data?

The study uses data from the FDA. It is based on amlodipine besylate (the active ingredients of Amlodipine besylate) and Amlodipine besylate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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