Amoxicillin and Vanishing bile duct syndrome - a phase IV clinical study of FDA data
Vanishing bile duct syndrome is found among people who take Amoxicillin, especially for people who are male, 2-9 old, have been taking the drug for < 1 month.
The phase IV clinical study analyzes which people take Amoxicillin and have Vanishing bile duct syndrome. It is created by eHealthMe based on reports of 74,593 people who have side effects when taking Amoxicillin from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
With medical big data and AI algorithms, eHealthMe enables everyone to run phase IV clinical trial to detect adverse drug outcomes and monitor effectiveness. Our original studies have been referenced on 600+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Most recently, phase IV clinial trails for COVID 19 vaccines have been added, check here.
74,593 people reported to have side effects when taking Amoxicillin.
Among them, 20 people (0.03%) have Vanishing bile duct syndrome.
What is Amoxicillin?
Amoxicillin has active ingredients of amoxicillin. It is often used in infection. eHealthMe is studying from 77,815 Amoxicillin users for its effectiveness, alternative drugs and more.
What is Vanishing bile duct syndrome?
Vanishing bile duct syndrome (loose collection of diseases which leads to the injury to hepatic bile ducts and eventual ductopenia) is found to be associated with 222 drugs and 160 conditions by eHealthMe.
Number of Amoxicillin and Vanishing bile duct syndrome reports submitted per year:
Time on Amoxicillin when people have Vanishing bile duct syndrome *:
- < 1 month: 100 %
- 1 - 6 months: 0.0 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
Gender of people who have Vanishing bile duct syndrome when taking Amoxicillin *:
- female: 20 %
- male: 80 %
Age of people who have Vanishing bile duct syndrome when taking Amoxicillin *:
- 0-1: 0.0 %
- 2-9: 73.68 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 10.53 %
- 40-49: 0.0 %
- 50-59: 0.0 %
- 60+: 15.79 %
Common drugs people take besides Amoxicillin *:
- Ursodeoxycholic Acid: 2 people, 10.00%
- S-Adenosyl-L-Methionine: 1 person, 5.00%
- Acetaminophen: 1 person, 5.00%
Common side effects people have besides Vanishing bile duct syndrome *:
- Erythema Multiforme (a type of hypersensitivity reaction): 15 people, 75.00%
- Cholestasis (a condition where bile cannot flow from the liver to the duodenum): 3 people, 15.00%
- Cholestatic Liver Injury (due to injury bile cannot floe from liver): 3 people, 15.00%
- Subacute Hepatic Failure: 3 people, 15.00%
- Hepatomegaly (abnormal enlargement of the liver): 2 people, 10.00%
- Fever: 2 people, 10.00%
- Rashes (redness): 2 people, 10.00%
- Blood Alkaline Phosphatase Increased: 2 people, 10.00%
- Blood Bilirubin Increased: 2 people, 10.00%
- Jaundice - Yellow Skin (a yellowish pigmentation of the skin): 2 people, 10.00%
Common conditions people have *:
- Fever: 12 people, 60.00%
- Lower Respiratory Tract Infection: 3 people, 15.00%
- Cellulitis (infection under the skin): 3 people, 15.00%
* Approximation only. Some reports may have incomplete information.
Do you take Amoxicillin and have Vanishing bile duct syndrome?Check whether Vanishing bile duct syndrome is associated with a drug or a condition
How to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Alternative drugs to, pros and cons of Amoxicillin:
- Amoxicillin (77,815 reports)
Vanishing bile duct syndrome treatments and more:
- Vanishing bile duct syndrome (811 reports)
COVID vaccines that are related to Vanishing bile duct syndrome:
- Vanishing bile duct syndrome in Moderna COVID Vaccine
- Vanishing bile duct syndrome in Pfizer BioNTech Covid Vaccine
- Vanishing bile duct syndrome in Johnson and Johnson Covid Vaccine
How severe was Vanishing bile duct syndrome and when was it recovered:
Expand to all the drugs that have ingredients of amoxicillin:
Common drugs associated with Vanishing bile duct syndrome:
All the drugs that are associated with Vanishing bile duct syndrome:
- Vanishing bile duct syndrome (222 drugs)
All the conditions that are associated with Vanishing bile duct syndrome:
- Vanishing bile duct syndrome (160 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on amoxicillin (the active ingredients of Amoxicillin) and Amoxicillin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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