Ampyra and Nail ridging - a phase IV clinical study of FDA data
Summary:
Nail ridging is reported only by a few people who take Ampyra.
The phase IV clinical study analyzes which people take Ampyra and have Nail ridging. It is created by eHealthMe based on reports of 75,087 people who have side effects while taking Ampyra from the FDA, and is updated regularly.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
75,087 people reported to have side effects when taking Ampyra.
Among them, 2 people (0.0%) have Nail ridging.
What is Ampyra?
Ampyra has active ingredients of dalfampridine. It is often used in multiple sclerosis. eHealthMe is studying from 75,227 Ampyra users for its effectiveness, alternative drugs and more.
What is Nail ridging?
Nail ridging (nail has raised ridges and is thin and curved inward) is found to be associated with 418 drugs and 278 conditions by eHealthMe.
Number of Ampyra and Nail ridging reports submitted per year:

Time on Ampyra when people have Nail ridging *:
- < 1 month: 0.0 %
- 1 - 6 months: 0.0 %
- 6 - 12 months: 100 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
Gender of people who have Nail ridging when taking Ampyra *:
- female: 100 %
- male: 0.0 %
Age of people who have Nail ridging when taking Ampyra *:
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 0.0 %
- 40-49: 0.0 %
- 50-59: 0.0 %
- 60+: 100 %
Common drugs people take besides Ampyra *:
- Spiriva: 1 person, 50.00%
- Magnesium: 1 person, 50.00%
- Ibuprofen: 1 person, 50.00%
- Copaxone: 1 person, 50.00%
- Calcium: 1 person, 50.00%
- Aleve: 1 person, 50.00%
- Advil: 1 person, 50.00%
Common side effects people have besides Nail ridging *:
- Sinusitis (inflammation of sinus): 2 people, 100.00%
- Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood): 2 people, 100.00%
- Hair Loss: 2 people, 100.00%
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 2 people, 100.00%
- Allergy To Animal: 2 people, 100.00%
- Weight Increased: 1 person, 50.00%
- Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 1 person, 50.00%
- Nosebleed (bleeding from nose): 1 person, 50.00%
- Hypotension (abnormally low blood pressure): 1 person, 50.00%
- Hepatic Enzyme Increased: 1 person, 50.00%
Common conditions people have *:
- Hypersensitivity: 1 person, 50.00%
- Gait Disturbance: 1 person, 50.00%
- Breathing Difficulty: 1 person, 50.00%
- Back Pain: 1 person, 50.00%
* Approximation only. Some reports may have incomplete information.
Do you take Ampyra and have Nail ridging?
Check whether Nail ridging is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
How severe was Nail ridging and when was it recovered:
Expand to all the drugs that have ingredients of dalfampridine:
Alternative drugs to, pros and cons of Ampyra:
- Ampyra (75,227 reports)
Common Ampyra side effects:
- Drug ineffective: 8,776 reports
- Weakness: 6,572 reports
- Fatigue (feeling of tiredness): 6,118 reports
- Urinary tract infection: 4,633 reports
Browse all side effects of Ampyra:
a b c d e f g h i j k l m n o p q r s t u v w x y zNail ridging treatments and more:
- Nail ridging (423 reports)
COVID vaccines that are related to Nail ridging:
- Nail ridging in Moderna COVID Vaccine
- Nail ridging in Pfizer BioNTech Covid Vaccine
- Nail ridging in Johnson and Johnson Covid Vaccine
All the drugs that are associated with Nail ridging:
- Nail ridging (418 drugs)
All the conditions that are associated with Nail ridging:
- Nail ridging (278 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on dalfampridine (the active ingredients of Ampyra) and Ampyra (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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