Anastrozole and Dupuytren's contracture - a phase IV clinical study of FDA data

Summary:

Dupuytren's contracture is found among people who take Anastrozole, especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years.

The phase IV clinical study analyzes which people take Anastrozole and have Dupuytren's contracture. It is created by eHealthMe based on reports of 13,396 people who have side effects when taking Anastrozole from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

With medical big data and AI algorithms, eHealthMe enables everyone to run phase IV clinical trial to detect adverse drug outcomes and monitor effectiveness. Our original studies have been referenced on 600+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Most recently, phase IV clinial trails for COVID 19 vaccines have been added, check here.

On Jun, 30, 2022

13,396 people reported to have side effects when taking Anastrozole.
Among them, 18 people (0.13%) have Dupuytren's contracture.

What is Anastrozole?

Anastrozole has active ingredients of anastrozole. It is often used in breast cancer. eHealthMe is studying from 13,833 Anastrozole users for its effectiveness, alternative drugs and more.

What is Dupuytren's contracture?

Dupuytren's contracture (thickening of the fibrous tissue layer underneath the skin of the palm and fingers) is found to be associated with 435 drugs and 194 conditions by eHealthMe.

Number of Anastrozole and Dupuytren's contracture reports submitted per year:

Could Anastrozole cause Dupuytren's contracture?

Time on Anastrozole when people have Dupuytren's contracture *:

Gender of people who have Dupuytren's contracture when taking Anastrozole *:

female: 100 %
male: 0.0 %

Age of people who have Dupuytren's contracture when taking Anastrozole *:

Common drugs people take besides Anastrozole *:

Metformin: 9 people, 50.00%
Canagliflozin: 9 people, 50.00%
Soltamox: 1 person, 5.56%

Common side effects people have besides Dupuytren's contracture *:

Trigger Finger: 10 people, 55.56%
Weakness: 9 people, 50.00%
Bone Disorder: 9 people, 50.00%
Bone Pain: 9 people, 50.00%
Cataract (clouding of the lens inside the eye): 9 people, 50.00%
Depression: 9 people, 50.00%
Dry Skin: 9 people, 50.00%
Headache (pain in head): 9 people, 50.00%
Heart Palpitations (feelings or sensations that your heart is pounding or racing): 9 people, 50.00%
Hiatal Hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm): 9 people, 50.00%

* Approximation only. Some reports may have incomplete information.

Do you take Anastrozole and have Dupuytren's contracture?

Check whether Dupuytren's contracture is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Manjunatha N, Ganjekar S, Mahendra JV, Kilara N, Srinivasa R, "Tardive Dyskinesia Associated With Anastrozole", The Journal of neuropsychiatry and clinical neurosciences, 2013 Jan .

Related studies

Alternative drugs to, pros and cons of Anastrozole:

Anastrozole (13,833 reports)

Dupuytren's contracture treatments and more:

Dupuytren's contracture (2,028 reports)

COVID vaccines that are related to Dupuytren's contracture:

How severe was Dupuytren's contracture and when was it recovered:

Dupuytren's contracture in Anastrozole

Expand to all the drugs that have ingredients of anastrozole:

Dupuytren's contracture and drugs with ingredients of anastrozole (18 reports)

Common drugs associated with Dupuytren's contracture:

Xiaflex: 137 reports

All the drugs that are associated with Dupuytren's contracture:

Dupuytren's contracture (435 drugs)

All the conditions that are associated with Dupuytren's contracture:

Dupuytren's contracture (194 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on anastrozole (the active ingredients of Anastrozole) and Anastrozole (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.