Aprepitant and Bowel obstruction - from FDA reports

Bowel obstruction is found among people who take Aprepitant, especially for people who are male, 60+ old , have been taking the drug for < 1 month, also take medication Palonosetron, and have Preventive health care. This study is created by eHealthMe based on reports of 2,273 people who have side effects when taking Aprepitant from FDA, and is updated regularly.

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On Oct, 13, 2018

2,273 people reported to have side effects when taking Aprepitant.
Among them, 29 people (1.28%) have Bowel obstruction

Number of reports submitted per year:

Could Aprepitant cause Bowel obstruction?

Time on Aprepitant when people have Bowel obstruction *:

Gender of people who have Bowel obstruction when taking Aprepitant *:

  • female: 46.43 %
  • male: 53.57 %

Age of people who have Bowel obstruction when taking Aprepitant *:

Top conditions involved for these people *:

  1. Preventive Health Care: 6 people, 20.69%
  2. Bronchial Carcinoma (lung cancer): 5 people, 17.24%
  3. Pancreatic Carcinoma Metastatic (pancreatic cancer- metastatic): 5 people, 17.24%
  4. Hodgkin's Lymphoma (cancer originating from white blood cells): 4 people, 13.79%
  5. Gastroesophageal Cancer: 3 people, 10.34%

Click here to view more results or personalize the results to your gender and age

Top co-used drugs for these people *:

  1. Dexamethasone: 9 people, 31.03%
  2. Palonosetron: 9 people, 31.03%
  3. Cisplatin: 8 people, 27.59%
  4. Ondansetron: 7 people, 24.14%
  5. Ibuprofen: 7 people, 24.14%

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Top other side effects for these people *:

  1. Dehydration (dryness resulting from the removal of water): 9 people, 31.03%
  2. Nausea And Vomiting: 9 people, 31.03%
  3. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 7 people, 24.14%
  4. Pneumonia: 6 people, 20.69%
  5. Thrombocytopenia (decrease of platelets in blood): 6 people, 20.69%

Click here to view more results or personalize the results to your gender and age

* Approximation only. Some reports may have incomplete information.

FDA reports used in this study

Do you have Bowel obstruction while taking Aprepitant?

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What would happen?

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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