Aprepitant and Pseudo-obstruction - intestinal - from FDA reports


Pseudo-obstruction - intestinal is found among people who take Aprepitant, especially for people who are female, 60+ old , have been taking the drug for < 1 month, also take medication Dexamethasone, and have Preventive health care. This review analyzes which people have Pseudo-obstruction - intestinal with Aprepitant. It is created by eHealthMe based on reports of 1,879 people who have side effects when taking Aprepitant from FDA , and is updated regularly.


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On Apr, 10, 2018

1,879 people reported to have side effects when taking Aprepitant.
Among them, 24 people (1.28%) have Pseudo-obstruction - intestinal


Number of reports submitted per year:

Could Aprepitant cause Pseudo-obstruction - intestinal?

Time on Aprepitant when people have Pseudo-obstruction - intestinal *:

  • < 1 month: 85.71 %
  • 1 - 6 months: 14.29 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Pseudo-obstruction - intestinal when taking Aprepitant *:

  • female: 54.17 %
  • male: 45.83 %

Age of people who have Pseudo-obstruction - intestinal when taking Aprepitant *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 8.7 %
  • 40-49: 4.35 %
  • 50-59: 26.09 %
  • 60+: 60.87 %

Top conditions involved for these people *:

  • Preventive Health Care: 6 people, 25.00%
  • Pancreatic Carcinoma Metastatic (pancreatic cancer- metastatic): 5 people, 20.83%
  • Hodgkin's Lymphoma (cancer originating from white blood cells): 4 people, 16.67%
  • Lung Cancer - Non-Small Cell (lung cancer): 3 people, 12.50%
  • Cough: 3 people, 12.50%

Top co-used drugs for these people *:

  • Palonosetron: 9 people, 37.50%
  • Dexamethasone: 9 people, 37.50%
  • Cisplatin: 8 people, 33.33%
  • Ondansetron: 7 people, 29.17%
  • Ibuprofen: 7 people, 29.17%

Top other side effects for these people *:

  • Nausea And Vomiting: 9 people, 37.50%
  • Dehydration (dryness resulting from the removal of water): 9 people, 37.50%
  • Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 7 people, 29.17%
  • White Blood Cell Count Decreased: 6 people, 25.00%
  • Ascites (accumulation of fluid in the abdominal cavity): 6 people, 25.00%

* Approximation only. Some reports may have incomplete information.

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