Arava and Enterocolitis infectious - a phase IV clinical study of FDA data


Enterocolitis infectious is found among people who take Arava, especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months.

The phase IV clinical study analyzes which people take Arava and have Enterocolitis infectious. It is created by eHealthMe based on reports of 67,744 people who have side effects when taking Arava from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Apr, 01, 2023

67,744 people reported to have side effects when taking Arava.
Among them, 11 people (0.02%) have Enterocolitis infectious.

What is Arava?

Arava has active ingredients of leflunomide. It is often used in rheumatoid arthritis. eHealthMe is studying from 68,104 Arava users for its effectiveness, alternative drugs and more.

What is Enterocolitis infectious?

Enterocolitis infectious is found to be associated with 602 drugs and 331 conditions by eHealthMe.

Number of Arava and Enterocolitis infectious reports submitted per year:

Could Arava cause Enterocolitis infectious?

Time on Arava when people have Enterocolitis infectious *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 87.5 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 12.5 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Enterocolitis infectious when taking Arava *:

  • female: 81.82 %
  • male: 18.18 %

Age of people who have Enterocolitis infectious when taking Arava *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 10 %
  • 60+: 90 %

Common drugs people take besides Arava *:

  1. Enbrel: 3 people, 27.27%
  2. Methotrexate: 3 people, 27.27%
  3. Fosamax: 2 people, 18.18%
  4. Alendronic Acid: 2 people, 18.18%
  5. Prednisolone: 2 people, 18.18%
  6. Allegra: 1 person, 9.09%
  7. Alupent: 1 person, 9.09%
  8. Biaxin: 1 person, 9.09%
  9. Combivent: 1 person, 9.09%
  10. Cyclosporine: 1 person, 9.09%

Common side effects people have besides Enterocolitis infectious *:

  1. Histiocytosis Haematophagic: 7 people, 63.64%
  2. Drug Rash With Eosinophilia And Systemic Symptoms (adverse drug reactions with rash): 7 people, 63.64%
  3. Dehydration (dryness resulting from the removal of water): 5 people, 45.45%
  4. Gastritis (inflammation of stomach): 4 people, 36.36%
  5. Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 3 people, 27.27%
  6. Gastrointestinal Haemorrhage (bleeding gastrointestinal tract): 3 people, 27.27%
  7. Oesophagitis (inflammation of oesophagus): 3 people, 27.27%
  8. Hypokalemia (low potassium): 3 people, 27.27%
  9. Visual Acuity Reduced (reduced clearness of vision): 3 people, 27.27%
  10. Cytolytic Hepatitis (dissolution or destruction of a liver cell): 3 people, 27.27%

Common conditions people have *:

  1. Latent Tuberculosis (hidden tuberculosis): 2 people, 18.18%
  2. Pain: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Arava and have Enterocolitis infectious?

Check whether Enterocolitis infectious is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Enterocolitis infectious and when was it recovered:

Expand to all the drugs that have ingredients of leflunomide:

Alternative drugs to, pros and cons of Arava:

Common Arava side effects:

Browse all side effects of Arava:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Enterocolitis infectious treatments and more:

COVID vaccines that are related to Enterocolitis infectious:

All the drugs that are associated with Enterocolitis infectious:

All the conditions that are associated with Enterocolitis infectious:

How the study uses the data?

The study uses data from the FDA. It is based on leflunomide (the active ingredients of Arava) and Arava (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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