Arthrotec and Chills - a phase IV clinical study of FDA data


Chills is found among people who take Arthrotec, especially for people who are female, 50-59 old, have been taking the drug for < 1 month.

The phase IV clinical study analyzes which people take Arthrotec and have Chills. It is created by eHealthMe based on reports of 10,889 people who have side effects when taking Arthrotec from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Mar, 18, 2023

10,889 people reported to have side effects when taking Arthrotec.
Among them, 172 people (1.58%) have Chills.

What is Arthrotec?

Arthrotec has active ingredients of diclofenac sodium; misoprostol. It is often used in arthritis. eHealthMe is studying from 11,305 Arthrotec users for its effectiveness, alternative drugs and more.

What is Chills?

Chills (felling of cold) is found to be associated with 3,744 drugs and 3,406 conditions by eHealthMe.

Number of Arthrotec and Chills reports submitted per year:

Could Arthrotec cause Chills?

Time on Arthrotec when people have Chills *:

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Gender of people who have Chills when taking Arthrotec*:

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Age of people who have Chills when taking Arthrotec *:

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Common drugs people take besides Arthrotec *:

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Common side effects people have besides Chills *:

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Common conditions people have *:

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* Approximation only. Some reports may have incomplete information.

Do you take Arthrotec and have Chills?

Check whether Chills is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Chills and when was it recovered:

Expand to all the drugs that have ingredients of diclofenac sodium; misoprostol:

Alternative drugs to, pros and cons of Arthrotec:

Common Arthrotec side effects:

Browse all side effects of Arthrotec:

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Chills treatments and more:

COVID vaccines that are related to Chills:

Common drugs associated with Chills:

All the drugs that are associated with Chills:

Common conditions associated with Chills:

All the conditions that are associated with Chills:

How the study uses the data?

The study uses data from the FDA. It is based on diclofenac sodium; misoprostol (the active ingredients of Arthrotec) and Arthrotec (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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