Aspirin and Xanthochromia - a phase IV clinical study of FDA data


Xanthochromia is reported only by a few people who take Aspirin.

The phase IV clinical study analyzes which people take Aspirin and have Xanthochromia. It is created by eHealthMe based on reports of 543,530 people who have side effects while taking Aspirin from the FDA, and is updated regularly.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On May, 30, 2023

543,530 people reported to have side effects when taking Aspirin.
Among them, 5 people (0.0%) have Xanthochromia.

What is Aspirin?

Aspirin has active ingredients of aspirin. It is often used in blood clots. eHealthMe is studying from 552,962 Aspirin users for its effectiveness, alternative drugs and more.

What is Xanthochromia?

Xanthochromia (yellowish appearance of cerebrospinal fluid) is found to be associated with 115 drugs and 68 conditions by eHealthMe.

Number of Aspirin and Xanthochromia reports submitted per year:

Could Aspirin cause Xanthochromia?

Time on Aspirin when people have Xanthochromia *:

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Xanthochromia when taking Aspirin *:

  • female: 0.0 %
  • male: 100 %

Age of people who have Xanthochromia when taking Aspirin *:

  • 0-1: 80 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 20 %
  • 60+: 0.0 %

Common drugs people take besides Aspirin *:

  1. Tegretol: 1 person, 20.00%
  2. Pantoprazole: 1 person, 20.00%
  3. Panadol: 1 person, 20.00%

Common side effects people have besides Xanthochromia *:

  1. Breathing - Slowed Or Stopped: 5 people, 100.00%
  2. Encephalopathy (functioning of the brain is affected by some agent or condition): 4 people, 80.00%
  3. Necrosis (the death of body tissue): 4 people, 80.00%
  4. Grand Mal Convulsion (a type of generalized seizure that affects the entire brain): 4 people, 80.00%
  5. Haematocrit Decreased: 3 people, 60.00%
  6. Blood Lactate Dehydrogenase Increased: 3 people, 60.00%
  7. Platelet Count Increased: 3 people, 60.00%
  8. Haemoglobin Decreased: 3 people, 60.00%
  9. Fever: 2 people, 40.00%
  10. Red Blood Cell Count Decreased: 2 people, 40.00%

Common conditions people have *:

  1. Pneumonia: 1 person, 20.00%
  2. Kawasaki's Disease (an autoimmune disease in which the medium-sized blood vessels throughout the body become inflamed): 1 person, 20.00%
  3. Hypersensitivity: 1 person, 20.00%
  4. Hyperlipidaemia (presence of excess lipids in the blood): 1 person, 20.00%
  5. Fever: 1 person, 20.00%
  6. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 1 person, 20.00%
  7. Atherosclerosis (disorder of the arteries): 1 person, 20.00%

* Approximation only. Some reports may have incomplete information.

Do you take Aspirin and have Xanthochromia?

Check whether Xanthochromia is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Related studies

How severe was Xanthochromia and when was it recovered:

Expand to all the drugs that have ingredients of aspirin:

Alternative drugs to, pros and cons of Aspirin:

Common Aspirin side effects:

Browse all side effects of Aspirin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Xanthochromia treatments and more:

COVID vaccines that are related to Xanthochromia:

All the drugs that are associated with Xanthochromia:

All the conditions that are associated with Xanthochromia:

How the study uses the data?

The study uses data from the FDA. It is based on aspirin (the active ingredients of Aspirin) and Aspirin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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